Catalog No.
DHD43401
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Humanized
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
Myelin-associated glycoprotein, MAG, Siglec-4a, GMA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P20916
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
GSK-249320, CAS: 1233953-61-1
Clone ID
Refanezumab
Proof-of-Concept Randomized Trial of the Monoclonal Antibody GSK249320 Versus Placebo in Stroke Patients, PMID: 28228578
First-time-in-human study with GSK249320, a myelin-associated glycoprotein inhibitor, in healthy volunteers, PMID: 23267856
Safety, pharmacokinetics, and pharmacodynamics of escalating repeat doses of GSK249320 in patients with stroke, PMID: 23471268
Effects of postinfarct myelin-associated glycoprotein antibody treatment on motor recovery and motor map plasticity in squirrel monkeys, PMID: 25931462
Proof-of-Concept Randomized Trial of the Monoclonal Antibody GSK249320 Versus Placebo in Stroke Patients., PMID:28228578
Effects of postinfarct myelin-associated glycoprotein antibody treatment on motor recovery and motor map plasticity in squirrel monkeys., PMID:25931462
Safety, pharmacokinetics, and pharmacodynamics of escalating repeat doses of GSK249320 in patients with stroke., PMID:23471268
First-time-in-human study with GSK249320, a myelin-associated glycoprotein inhibitor, in healthy volunteers., PMID:23267856
For research use only. Not for human or drug use.
