Catalog No.
YHJ76601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg258-Pro467
Predicted molecular weight
25.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UHI8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
A disintegrin and metalloproteinase with thrombospondin motifs 1, ADAM-TS 1, ADAM-TS1, ADAMTS1, METH1, METH-1, KIAA1346, ADAMTS-1
Genome-Wide Identification and Expression Analysis of Zona Pellucida (ZP) Gene Family in Cynoglossus semilaevis., PMID:40508155
ADAMTS-1, a multifunctional proteinase, in the uterus of both estrous cycle rats and ovariectomized rats can be regulated via hormones., PMID:40461860
Loss of the extracellular protease ADAMTS1 reveals an antitumorigenic program involving the action of NIDOGEN-1 on macrophage polarization., PMID:40401531
Secreted Protein Acidic and Rich in Cysteine (SPARC) Induced by the Renin-Angiotensin System Causes Endothelial Inflammation in the Early Stages of Hypertensive Vascular Injury., PMID:40362650
Suppressing SPARC gene with siRNA exerts therapeutic effects and inhibits MMP-2/9 and ADAMTS1 overexpression in a murine model of ischemia/reperfusion-induced acute kidney injury., PMID:40288820
Study on the common mechanisms of gastroesophageal reflux disease and interstitial lung disease., PMID:40209518
A novel basement membrane-related gene signature for predicting prognosis of HNSCC., PMID:39833042
A cardiac transcriptional enhancer is repurposed during regeneration to activate an anti-proliferative program., PMID:39803985
Gene expression and immunohistochemistry analysis of ADAMTS-1 and its substrates in odontogenic keratocyst., PMID:39762885
Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease., PMID:39672391
The matrix protease ADAMTS1 is transcriptionally activated by KLF6 and contributes to cardiac fibrosis in non-ischemic cardiomyopathy., PMID:39643035
Topical application of 666-15, a potent inhibitor of CREB, alleviates alkali-induced corneal neovascularization., PMID:39571779
Recombinant ADAMTS1 promotes muscle cell differentiation and alleviates muscle atrophy by repressing NOTCH1., PMID:39567207
Exploring Pathogenic Genes in Frozen Shoulder through weighted gene co-expression network analysis and Mendelian Randomization., PMID:39512681
ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-β1 activation., PMID:39448254
MiR-29b inhibits COC expansion and oocyte in vitro maturation via induction of ROS by targeting CYCS., PMID:39342691
The oncogenic ADAMTS1-VCAN-EGFR cyclic axis drives anoikis resistance and invasion in renal cell carcinoma., PMID:39333870
Electroacupuncture promotes angiogenesis by regulating miR-142-5p and activating ADAMTS1/PI3K/AKT pathway in ischemic stroke rats., PMID:39318307
Astrocytes originated from neural stem cells drive the regenerative remodeling of pathologic CSPGs in spinal cord injury., PMID:39303705
Insight in the (Phospho)proteome of Vascular Smooth Muscle Cells Derived From Patients With Abdominal Aortic Aneurysm Reveals Novel Disease Mechanisms., PMID:39206541
Investigation roles of Adamts1 and Adamts5 in scleral fibroblasts under hypoxia and mice with form-deprived myopia., PMID:39122105
Visfatin impact on the proteome of porcine luteal cells during implantation., PMID:38918475
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development., PMID:38750698
Dynamics of N6-methyladenosine modification during aging and their potential roles in the degeneration of intervertebral disc., PMID:38283178
Cyclic increase in the ADAMTS1-L1CAM-EGFR axis promotes the EMT and cervical lymph node metastasis of oral squamous cell carcinoma., PMID:38263290
Comparative Transcriptome Analysis Identifies Desmoglein-3 as a Potential Oncogene in Oral Cancer Cells., PMID:38067138
ADAMTS-1 has nuclear localization in cells with epithelial origin and leads to decreased cell migration., PMID:37951335
Glucocorticoid signaling and the impact of high-fat diet on adipogenesis in vivo., PMID:37944652
Molecular analyses of ADAMTS-1, -4, -5, and IL-17 a cytokine relationship in patients with ulcerative colitis., PMID:37798683
Molecular Motifs in Vascular Morphogenesis: Vascular Endothelial Growth Factor A (VEGFA) as the Leading Promoter of Angiogenesis., PMID:37569543
Exposure to a phthalate mixture disrupts ovulatory progesterone receptor signaling in human granulosa cells in vitro†., PMID:37552060
Genes with dual proto-oncogene and tumor suppressor gene activities are frequently altered by protein losses in colon cancers., PMID:37429176
Reprogramming of VEGF-mediated extracellular matrix changes through autocrine signaling., PMID:37389973
ADAMTS Proteases: Importance in Animal Reproduction., PMID:37372361
Identification of novel genes associated with exercise and calorie restriction effects in skeletal muscle., PMID:37310402
Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1., PMID:37254794
Fibrillin-1 regulates endothelial sprouting during angiogenesis., PMID:37252964
ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1., PMID:37170317
ADAMTS1 induces epithelial-mesenchymal transition pathway in non-small cell lung cancer by regulating TGF-β., PMID:36947712
Re-Exploring the Inflammation-Related Core Genes and Modules in Cerebral Ischemia., PMID:36867343
Analysis of the Genetic Relationship between Atherosclerosis and Non-Alcoholic Fatty Liver Disease through Biological Interaction Networks., PMID:36835545
Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity., PMID:36829979
The C-terminal domains of ADAMTS1 contain exosites involved in its proteoglycanase activity., PMID:36813235
ADAMTS1 as potential prognostic biomarker promotes malignant invasion of glioma., PMID:36371587
Gene Expression and Immunochemistry Analysis of ADAMTS-1 and Versican in Ameloblastoma., PMID:36338393
Estrogen Regulates the Expression and Localization of YAP in the Uterus of Mice., PMID:36077170
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage., PMID:36028175
Induction of A Disintegrin and Metalloproteinase with Thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer's disease risk., PMID:36016856
The role of serum ADAMTS-1 levels in Hyperemesis Gravidarum., PMID:35725415
Cell-Based HIF1α Gene Therapy Reduces Myocardial Scar and Enhances Angiopoietic Proteome, Transcriptomic and miRNA Expression in Experimental Chronic Left Ventricular Dysfunction., PMID:35646882
For research use only. Not for human or drug use.
