Catalog No.
YHJ76001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-His72
Predicted molecular weight
35.58 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UHE8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PRSS24, STEAP1, STEAP, Metalloreductase STEAP1, Six-transmembrane epithelial antigen of prostate 1
Advances in Targeted Therapy for Metastatic Prostate Cancer., PMID:40299225
Exploring STEAP1 Expression in Prostate Cancer Cells in Response to Androgen Deprivation and in Small Extracellular Vesicles., PMID:40287951
Thermal potentiation improves IFN-γ production but not cytotoxicity in human CAR-T cells., PMID:40270044
STEAP Proteins: Roles in disease biology and potential for therapeutic intervention., PMID:40185436
Targeting the tumour cell surface in advanced prostate cancer., PMID:40169837
Contribution of cuproptosis and immune-related genes to idiopathic pulmonary fibrosis disease., PMID:39991151
Prostate Extracellular Vesicles and Prognostic Biomarkers of Clinically Significant Prostate Cancer: A Prospective Single-Institution Pilot Study., PMID:39980247
A novel prostate cancer-specific fluorescent probe based on extracellular vesicles targeting STEAP1 applied in fluorescence guided surgery., PMID:39894263
Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors., PMID:39835140
Proteomics and Metabolomics Study on the Responses of Sertoli Cells Infected With Brucella and Its bvfA-Deletion Strains., PMID:39512196
Developmental Therapeutics in Metastatic Prostate Cancer: New Targets and New Strategies., PMID:39272956
METTL14/IGF2BP2-MEDIATED M6A MODIFICATION OF STEAP1 AGGRAVATES ACUTE LUNG INJURY INDUCED BY SEPSIS., PMID:39193903
STEAP1 as a potential target for new therapies in prostate cancer., PMID:38805316
T-Cell redirecting bispecific antibodies: a review of a novel class of immuno-oncology for advanced prostate cancer., PMID:38801069
Antibody Drug Conjugates in Urological Cancers: A Review of the Current Landscape., PMID:38652426
Bispecific T-cell Engagers in Metastatic Castration-Resistant Prostate Cancer., PMID:38213299
Comparative Evaluation of STEAP1 Targeting Chimeric Antigen Receptors with Different Costimulatory Domains and Spacers., PMID:38203757
A novel prognostic signature and therapy guidance for hepatocellular carcinoma based on STEAP family., PMID:38191397
Six Transmembrane Epithelial Antigen 1 as a Prognostic Biomarker in Carcinomas: A Meta-Analysis., PMID:38062846
Mechanism of stepwise electron transfer in six-transmembrane epithelial antigen of the prostate (STEAP) 1 and 2., PMID:37983176
Xaluritamig, a STEAP1 × CD3 XmAb 2+1 Immune Therapy for Metastatic Castration-Resistant Prostate Cancer: Results from Dose Exploration in a First-in-Human Study., PMID:37861461
AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer., PMID:37861452
Surface and Global Proteome Analyses Identify ENPP1 and Other Surface Proteins as Actionable Immunotherapeutic Targets in Ewing Sarcoma., PMID:37812652
Integrated analysis of transcriptome and proteome for exploring mechanism of promoting proliferation of equine satellite cells associated with leucine., PMID:37633218
Proteomic analysis of STEAP1 knockdown in human LNCaP prostate cancer cells., PMID:37315586
Establishment of cancer-associated fibroblasts-related subtypes and prognostic index for prostate cancer through single-cell and bulk RNA transcriptome., PMID:37270661
Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells., PMID:37209327
Development of a novel electrochemical biosensor based on plastic antibodies for detection of STEAP1 biomarker in cancer., PMID:37192590
STEAP1 Knockdown Decreases the Sensitivity of Prostate Cancer Cells to Paclitaxel, Docetaxel and Cabazitaxel., PMID:37047621
Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy., PMID:37041154
Antibody-Drug Conjugates in Prostate Cancer: A Systematic Review., PMID:36874351
Prognostic Significance of Iron Metabolism Related Genes in Human Lung Adenocarcinoma., PMID:36860893
Development of a TGFβ-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy., PMID:36830995
Specific Six-Transmembrane Epithelial Antigen of the Prostate 1 Capture with Gellan Gum Microspheres: Design, Optimization and Integration., PMID:36768273
STEAP1 regulation and its influence modulating the response of LNCaP prostate cancer cells to bicalutamide, enzalutamide and apalutamide., PMID:36660947
Intravenous administration of viral vectors expressing prostate cancer antigens enhances the magnitude and functionality of CD8+ T cell responses., PMID:36323434
A chromatographic network for the purification of detergent-solubilized six-transmembrane epithelial antigen of the prostate 1 from Komagataella pastoris mini-bioreactor lysates., PMID:36323109
Antibody-Drug Conjugates in Prostate Cancer: Where Are we?, PMID:35999150
Broiler responses to copper levels and sources: growth, tissue mineral content, antioxidant status and mRNA expression of genes involved in lipid and protein metabolism., PMID:35698226
Expression and prognostic analyses of the significance of STEAP1 and STEAP2 in lung cancer., PMID:35346237
The Prognostic Value and Immunological Role of STEAP1 in Pan-Cancer: A Result of Data-Based Analysis., PMID:35313641
Regulatory Roles of Six-Transmembrane Epithelial Antigen of the Prostate Family Members in the Occurrence and Development of Malignant Tumors., PMID:34778263
Analysis of Shared Genetic Regulatory Networks for Alzheimer's Disease and Epilepsy., PMID:34697589
Novel Redirected T-Cell Immunotherapies for Advanced Prostate Cancer., PMID:34675084
Predictive potential of STEAP family for survival, immune microenvironment and therapy response in glioma., PMID:34649092
Enhanced Stability of Detergent-Free Human Native STEAP1 Protein from Neoplastic Prostate Cancer Cells upon an Innovative Isolation Procedure., PMID:34576175
Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy., PMID:34497115
Fusion Protein Vaccine Based on Ag85B and STEAP1 Induces a Protective Immune Response against Prostate Cancer., PMID:34358202
Identification of a New Transcriptional Co-Regulator of STEAP1 in Ewing's Sarcoma., PMID:34073779
Impact of glycerol feeding profiles on STEAP1 biosynthesis by Komagataella pastoris using a methanol-inducible promoter., PMID:34059939
For research use only. Not for human or drug use.
