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Research Grade Birtamimab

Catalog #:   DHC65501 Specific References (19) DATASHEET
Host species: Humanized
Isotype: IgG1-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHC65501

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

SAA, Serum amyloid A-1 protein, SAA1, Amyloid fibril protein AA

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P0DJI8

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

2A4, ELT1-01, NEOD-001, CAS: 1608108-91-3

Clone ID

Birtamimab

Data Image
  • SDS-PAGE
    SDS PAGE for Birtamimab
References

Novel Approaches for the Management of AL Amyloidosis, PMID: 29951831

Beyond NEOD001 for systemic light-chain amyloidosis, PMID: 30242086

Market watch: Upcoming market catalysts in Q2 2018, PMID: 29588523

First-in-Human Phase I/II Study of NEOD001 in Patients With Light Chain Amyloidosis and Persistent Organ Dysfunction, PMID: 26858336

Organ response in patients with AL amyloidosis treated with NEOD001, an amyloid-directed monoclonal antibody, PMID: 27648922

Etiological Treatment of Cardiac Amyloidosis: Standard of Care and Future Directions., PMID:40232627

New therapies to treat cardiac amyloidosis., PMID:39819772

Current and Emerging Immunotherapies for Systemic AL Amyloidosis., PMID:39327239

The mechanism of action, pharmacological characteristics, and clinical utility of the amyloid depleter birtamimab for the potential treatment of AL amyloidosis., PMID:38600883

Novel monoclonal antibodies: A really specific therapy for light chain amyloidosis., PMID:38590272

Birtamimab: a new amyloidosis treatment?, PMID:37796521

Birtamimab plus standard of care in light-chain amyloidosis: the phase 3 randomized placebo-controlled VITAL trial., PMID:37366170

Advancements and future trends of immunotherapy in light-chain amyloidosis., PMID:36696931

Multidisciplinary supportive care in systemic light chain amyloidosis., PMID:35593003

Beyond NEOD001 for systemic light-chain amyloidosis., PMID:30242086

Novel Approaches for the Management of AL Amyloidosis., PMID:29951831

Market watch: Upcoming market catalysts in Q2 2018., PMID:29588523

Organ response in patients with AL amyloidosis treated with NEOD001, an amyloid-directed monoclonal antibody., PMID:27648922

First-in-Human Phase I/II Study of NEOD001 in Patients With Light Chain Amyloidosis and Persistent Organ Dysfunction., PMID:26858336

Datasheet

Document Download

Research Grade Birtamimab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Birtamimab [DHC65501]
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