Catalog No.
YHJ74201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ile170
Predicted molecular weight
20.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UBY9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HSPB7, CVHSP, Cardiovascular heat shock protein, cvHsp, HspB7, Heat shock protein beta-7
Selenium alleviates cadmium-induced Golgi stress via HSPB7/GM130/CX-43 axis in the heart of sheep., PMID:40490057
Filamin C dimerisation is regulated by HSPB7., PMID:40312381
Interaction of small heat shock proteins with BAG3., PMID:39814164
LINC01936 inhibits the proliferation and metastasis of lung squamous cell carcinoma probably by EMT signaling and immune infiltration., PMID:38084139
Interaction of the C-terminal immunoglobulin-like domains (Ig 22-24) of filamin C with human small heat shock proteins., PMID:38016530
Heat shock protein B7 (HSPB7) inhibits lung adenocarcinoma progression by inhibiting glycolysis., PMID:37732539
Hmga1-overexpressing lentivirus protects against osteoporosis by activating the Wnt/β-catenin pathway in the osteogenic differentiation of BMSCs., PMID:37555233
Identification genetic variations in some heat shock protein genes of Tali goat breed and study their structural and functional effects on relevant proteins., PMID:37530404
[The anti-inflammatory effect of electroacupuncture in mice with spinal cord injury and molecular mechanism based on transcriptome sequencing technology]., PMID:37518961
HSPB7 oppositely regulates human mesenchymal stromal cell-derived osteogenesis and adipogenesis., PMID:37170285
Efficacy of electroacupunture at Zusanli (ST36) on jumping-injured muscle based on transcriptome sequencing and genes analysis., PMID:36994520
α-Crystallin Domains of Five Human Small Heat Shock Proteins (sHsps) Differ in Dimer Stabilities and Ability to Incorporate Themselves into Oligomers of Full-Length sHsps., PMID:36674601
Role of Small Heat Shock Proteins in the Remodeling of Actin Microfilaments., PMID:36171660
Is the small heat shock protein HSPB7 (cvHsp) a genuine actin-binding protein?, PMID:35977674
Heat Shock Protein B7 Inhibits the Progression of Endometrial Carcinoma by Inhibiting PI3K/AKT/mTOR Pathway., PMID:35859224
Sodium butyrate inhibits oral squamous cell carcinoma proliferation and invasion by regulating the HDAC1/HSPB7 axis., PMID:35652621
Estimation of the proteome affecting changes in tenderness of yak meat during storage by label-free mass spectrometry., PMID:35441809
An investigation to identify tumor microenvironment-related genes of prognostic value in lung squamous cell carcinoma based on The Cancer Genome Atlas., PMID:35116510
Quaternary Structure and Hetero-Oligomerization of Recombinant Human Small Heat Shock Protein HspB7 (cvHsp)., PMID:34360542
Atrial heat shock protein levels are associated with early postoperative and persistence of atrial fibrillation., PMID:34186247
Maternal protein restriction changes structural and metabolic gene expression in the skeletal muscle of aging offspring rats., PMID:33843034
Cardio-Vascular Heat Shock Protein (cvHsp, HspB7), an Unusual Representative of Small Heat Shock Protein Family., PMID:33827396
Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23., PMID:33677556
HSPB7 regulates osteogenic differentiation of human adipose derived stem cells via ERK signaling pathway., PMID:33097082
Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation., PMID:32887649
PINK1-PRKN mitophagy suppression by mangiferin promotes a brown-fat-phenotype via PKA-p38 MAPK signalling in murine C3H10T1/2 mesenchymal stem cells., PMID:32289346
Deletion of metal transporter Zip14 (Slc39a14) produces skeletal muscle wasting, endotoxemia, Mef2c activation and induction of miR-675 and Hspb7., PMID:32132660
A Missense Mutation of the HSPB7 Gene Associated with Heat Tolerance in Chinese Indicine Cattle., PMID:31416175
The N terminus of the small heat shock protein HSPB7 drives its polyQ aggregation-suppressing activity., PMID:31097540
Effect of heat-shock protein B7 on oxidative stress in adipocytes from preruminant calves., PMID:30954260
The BAG3-dependent and -independent roles of cardiac small heat shock proteins., PMID:30830872
HSPB7 gene polymorphism associated with anthropometric parameters of obesity and fat intake in a Central European population., PMID:30660137
Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages., PMID:29763919
SRARP and HSPB7 are epigenetically regulated gene pairs that function as tumor suppressors and predict clinical outcome in malignancies., PMID:29577611
The small heat shock proteins, especially HspB4 and HspB5 are promising protectants in neurodegenerative diseases., PMID:29425965
Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor., PMID:29397684
Hspb7 is a cardioprotective chaperone facilitating sarcomeric proteostasis., PMID:29331499
HSPB7 is indispensable for heart development by modulating actin filament assembly., PMID:29078393
Dynamic adaptation of myocardial proteome during heart failure development., PMID:28973020
HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity., PMID:28827800
Cryptotanshinone promotes commitment to the brown adipocyte lineage and mitochondrial biogenesis in C3H10T1/2 mesenchymal stem cells via AMPK and p38-MAPK signaling., PMID:28807877
Upregulation and phosphorylation of HspB1/Hsp25 and HspB5/αB-crystallin after transient middle cerebral artery occlusion in rats., PMID:28425051
The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins., PMID:27909051
Regulation of Hspb7 by MEF2 and AP-1: implications for Hspb7 in muscle atrophy., PMID:27632998
Association between polymorphisms of the HSPB7 gene and Cheyne-Stokes respiration with central sleep apnea in patients with dilated cardiomyopathy and congestive heart failure., PMID:27441470
Phosphorylated Heat Shock Protein 20 (HSPB6) Regulates Transforming Growth Factor-α-Induced Migration and Invasion of Hepatocellular Carcinoma Cells., PMID:27046040
HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles., PMID:26929074
Distinguishing aggregate formation and aggregate clearance using cell-based assays., PMID:26818841
Involvement of BAG3 and HSPB7 loci in various etiologies of systolic heart failure: Results of a European collaboration assembling more than 2000 patients., PMID:25889438
Quantitative Proteomics of Human Fibroblasts with I1061T Mutation in Niemann-Pick C1 (NPC1) Protein Provides Insights into the Disease Pathogenesis., PMID:25873482