Catalog No.
YHJ72001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu116-Ala302
Predicted molecular weight
23.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UBB4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATXN10, SCA10, Brain protein E46 homolog, Ataxin-10, Spinocerebellar ataxia type 10 protein
Target Identification of Ginsenosides Against Cognitive Impairment by Using Mass Spectrometry-Based Cellular Thermal Shift Assay (CETSA)., PMID:40323441
Spinocerebellar Ataxia Type 10 (SCA 10) in Brazil., PMID:40232546
A strategy for multimodal integration of transcriptomics, proteomics, and radiomics data for the prediction of recurrence in patients with IDH-mutant gliomas., PMID:40214613
The impact of interrupted ATXN10 expansions on clinical findings of spinocerebellar ataxia type 10., PMID:40067487
Novel Intermediate ATXN10 Alleles in the Healthy Peruvian Population: A Matter of Indigenous American Ethnic Origin., PMID:39918768
ATXN10 Gene Expansions in Mexican Patients with Ataxia Without Epilepsy., PMID:39820777
Evaluating the expression pattern of ATXN1 and CDC42EP1 genes and related long noncoding RNAs in oral squamous cell carcinoma., PMID:39002033
Extended haplotype with rs41524547-G defines the ancestral origin of SCA10., PMID:38832639
Genetic Regulation of DNA Methylation Yields Novel Discoveries in GWAS of Colorectal Cancer., PMID:35247911
A FEMALE CASE OF SPINOCEREBELLAR ATAXIA TYPE 10 WITH SUICIDAL BEHAVIOR AND ENDOCRINPATHIES ASSOCIATED WITH A MASSIVE EXPANSION (ATTCT) OF THE GENE ATXN10., PMID:35103298
ATXN10 Is Required for Embryonic Heart Development and Maintenance of Epithelial Cell Phenotypes in the Adult Kidney and Pancreas., PMID:34970537
Cancer-A Major Cardiac Comorbidity With Implications on Cardiovascular Metabolism., PMID:34899373
Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1., PMID:34858081
Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation., PMID:34815492
Two quantitative trait loci are associated with recapping of Varroa destructor-infested brood cells in Apis mellifera mellifera., PMID:34729804
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology., PMID:34467244
Response to ATXN10 Microsatellite Distribution in a Peruvian Amerindian Population., PMID:33728569
Frequency of spinocerebellar ataxia mutations in patients with multiple system atrophy., PMID:33502644
Fraternal twins with Phelan-McDermid syndrome not involving the SHANK3 gene: case report and literature review., PMID:33023580
Minidumbbell structures formed by ATTCT pentanucleotide repeats in spinocerebellar ataxia type 10., PMID:32520333
'Corrigendum to "Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia" [Molecular Metabolism 5 (2) (2015) 67-78]'., PMID:32244184
Pulse-Field capillary electrophoresis of repeat-primed PCR amplicons for analysis of large repeats in Spinocerebellar Ataxia Type 10., PMID:32160188
Founder Effects of Spinocerebellar Ataxias in the American Continents and the Caribbean., PMID:32086717
Genetic Analysis of Hereditary Ataxias in Peru Identifies SCA10 Families with Incomplete Penetrance., PMID:31900855
Clinical and Genetic Evaluation of Spinocerebellar Ataxia Type 10 in 16 Brazilian Families., PMID:31377949
ATXN10 Microsatellite Distribution in a Peruvian Amerindian Population., PMID:31342269
Detailed analysis of HTT repeat elements in human blood using targeted amplification-free long-read sequencing., PMID:29932473
Clinical and molecular characterization of an emerging chromosome 22q13.31 microdeletion syndrome., PMID:29193617
Ataxin-10 is involved in Golgi membrane dynamics., PMID:29169923
In-depth phenotyping of lymphoblastoid cells suggests selective cellular vulnerability in Marinesco-Sjögren syndrome., PMID:28978133
Haplotype Study in SCA10 Families Provides Further Evidence for a Common Ancestral Origin of the Mutation., PMID:28905220
Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease., PMID:28676412
Spinocerebellar ataxia type 10: common haplotype and disease progression rate in Peru and Brazil., PMID:28560845
First report of a Japanese family with spinocerebellar ataxia type 10: The second report from Asia after a report from China., PMID:28542277
Inheritance patterns of ATCCT repeat interruptions in spinocerebellar ataxia type 10 (SCA10) expansions., PMID:28423040
Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10., PMID:27248057
Temporal proteomic profiling of Chlamydia trachomatis-infected HeLa-229 human cervical epithelial cells., PMID:27134121
Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia., PMID:26909315
SMRT Sequencing of Long Tandem Nucleotide Repeats in SCA10 Reveals Unique Insight of Repeat Expansion Structure., PMID:26295943
Crystallographic and Computational Analyses of AUUCU Repeating RNA That Causes Spinocerebellar Ataxia Type 10 (SCA10)., PMID:26039897
Spinocerebellar ataxia-10 with paranoid schizophrenia., PMID:25745322
Aurora B-dependent phosphorylation of Ataxin-10 promotes the interaction between Ataxin-10 and Plk1 in cytokinesis., PMID:25666058
Bolivian kindred with combined spinocerebellar ataxia types 2 and 10., PMID:25630585
[Advances in repeat-primed PCR assay for the genetic diagnosis of dynamic mutation diseases with large pathogenic expansions]., PMID:25567872
Spinocerebellar ataxia type 10 in Peru: the missing link in the Amerindian origin of the disease., PMID:24935856
Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling., PMID:24882704
Identification of small ubiquitin-like modifier substrates with diverse functions using the Xenopus egg extract system., PMID:24797264
Repeat interruptions in spinocerebellar ataxia type 10 expansions are strongly associated with epileptic seizures., PMID:24318420
For research use only. Not for human or drug use.
