Catalog No.
YHJ69001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu1221-Leu1536
Predicted molecular weight
39.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NYU2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GT, UGT1, hUGT1, UDP--Glc:glycoprotein glucosyltransferase, UGGT, UGGT1, UGTR, UDP-glucose:glycoprotein glucosyltransferase 1, UGCGL1, UDP-glucose ceramide glucosyltransferase-like 1
Novel lncRNA UGGT1-AS1 Regulates UGGT1 Expression in Breast Cancer Cell Line., PMID:40507918
Expression, purification, and enzymatic characterization of human UDP-glucose:glycoprotein glucosyltransferase-selenoprotein F complex from Sf9 insect cells., PMID:40250575
Endocytosis, endoplasmic reticulum, actin cytoskeleton affected in tilapia liver under polystyrene microplastics and BDE153 acute co-exposure., PMID:39725183
UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins., PMID:39654396
Identification of biological pathways and putative candidate genes for residual feed intake in a tropically adapted beef cattle breed by plasma proteome analysis., PMID:39638144
Clinically aggressive follicular cell-derived thyroid carcinoma: A comprehensive series with histomolecular characterization and discovery of novel gene fusions., PMID:39490534
Targeted metabolomics of muscle amino acid profles and hepatic transcriptomics analyses in grass carp (Ctenopharyngodon idellus) fed with broad beans., PMID:39386830
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer., PMID:39385083
Insights into the interaction between UGGT, the gatekeeper of folding in the ER, and its partner, the selenoprotein SEP15., PMID:39133860
Discovery of biomarkers in the psoriasis through machine learning and dynamic immune infiltration in three types of skin lesions., PMID:38803495
Rescue of secretion of rare-disease-associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells., PMID:38272446
Analysis of the Tropism of SARS-CoV-2 Based on the Host Interactome of the Spike Protein., PMID:37939376
The ER folding sensor UGGT1 acts on TAPBPR-chaperoned peptide-free MHC I., PMID:37345806
Selective involvement of UGGT variant: UGGT2 in protecting mouse embryonic fibroblasts from saturated lipid-induced ER stress., PMID:36508673
Analysis of Selenoprotein F Binding to UDP-Glucose:Glycoprotein Glucosyltransferase (UGGT) by a Photoreactive Crosslinker., PMID:36219527
The introduction of an N-glycosylation site into prochymosin greatly enhances its production and secretion by Pichia pastoris., PMID:36042512
UDP-glucose, cereblon-dependent proinsulin degrader., PMID:36028536
Upregulation of ribosome complexes at the blood-brain barrier in Alzheimer's disease patients., PMID:35766008
R1526 residue in arginine/proinsulin binding domain of UGGT1 is involved in proinsulin binding., PMID:35613513
N-glycan processing selects ERAD-resistant misfolded proteins for ER-to-lysosome-associated degradation., PMID:34152647
Glycosylation limits forward trafficking of the tetraspan membrane protein PMP22., PMID:33933451
Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1., PMID:33909026
Tauroursodeoxycholic acid attenuates cisplatin-induced ototoxicity by inhibiting the accumulation and aggregation of unfolded or misfolded proteins in the endoplasmic reticulum., PMID:33631298
The Host Interactome of Spike Expands the Tropism of SARS-CoV-2., PMID:33619478
Quantitative glycoproteomics reveals cellular substrate selectivity of the ER protein quality control sensors UGGT1 and UGGT2., PMID:33320095
Glycan dependent refolding activity of ER glucosyltransferase (UGGT)., PMID:32858085
Genetic Analyses of Contributions of Viral Interleukin-6 Interactions and Signaling to Human Herpesvirus 8 Productive Replication., PMID:32669340
UGGT1 retains proinsulin in the endoplasmic reticulum in an arginine dependent manner., PMID:32423812
Metabolic syndrome perturbs deglucosylation and reglucosylation in the glycoprotein folding cycle., PMID:32232844
Amentoflavone induces cell cycle arrest, apoptosis, and autophagy in BV-2 cells., PMID:31585918
SR-BI Interactome Analysis Reveals a Proviral Role for UGGT1 in Hepatitis C Virus Entry., PMID:31551978
Proteome analysis of non-small cell lung cancer cell line secretomes and patient sputum reveals biofluid biomarker candidates for cisplatin response prediction., PMID:30710758
Maize Sep15-like functions in endoplasmic reticulum and reactive oxygen species homeostasis to promote salt and osmotic stress resistance., PMID:30577086
Quantitative proteomics and biochemical analyses reveal the role of endoplasmin in the regulation of the expression and secretion of A Disintegrin And Metalloproteinase 12., PMID:29729432
Human Herpesvirus 8 Interleukin-6 Interacts with Calnexin Cycle Components and Promotes Protein Folding., PMID:28878084
UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication., PMID:28545059
TAPBPR bridges UDP-glucose:glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway., PMID:28425917
Interaction of FAM5C with UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1): Implication of N-glycosylation in FAM5C secretion., PMID:28351617
Effects of domain composition on catalytic activity of human UDP-glucose:glycoprotein glucosyltransferases., PMID:27496766
Chemical Approaches to Elucidate Enzymatic Profiles of UDP-Glucose: Glycoprotein Glucosyltransferase., PMID:27373624
Profiling Aglycon-Recognizing Sites of UDP-glucose:glycoprotein Glucosyltransferase by Means of Squarate-Mediated Labeling., PMID:26196150
The relationship between glycan structures and expression levels of an endoplasmic reticulum-resident glycoprotein, UDP-glucose: Glycoprotein glucosyltransferase 1., PMID:25935482
Mutation specific functions of EGFR result in a mutation-specific downstream pathway activation., PMID:25754235
A novel UGGT1 and p97-dependent checkpoint for native ectodomains with ionizable intramembrane residue., PMID:25694454
Functional analysis of endoplasmic reticulum glucosyltransferase (UGGT): Synthetic chemistry's initiative in glycobiology., PMID:25481681
Glycan structure and site of glycosylation in the ER-resident glycoprotein, uridine 5'-diphosphate-glucose: glycoprotein glucosyltransferases 1 from rat, porcine, bovine, and human., PMID:25094044
Both isoforms of human UDP-glucose:glycoprotein glucosyltransferase are enzymatically active., PMID:24415556
Progesterone regulates the expression and activity of two mouse isoforms of the glycoprotein folding sensor UDP-Glc: glycoprotein glucosyltransferase (UGGT)., PMID:24140206
UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum., PMID:23864712
The two Caenorhabditis elegans UDP-glucose:glycoprotein glucosyltransferase homologues have distinct biological functions., PMID:22073243
For research use only. Not for human or drug use.
