Catalog No.
YHJ66701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys54-Leu437
Predicted molecular weight
44.68 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NRS4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CAPH2, Transmembrane protease serine 4, TMPRSS3, TMPRSS4, Channel-activating protease 2, Membrane-type serine protease 2, MT-SP2
Pathological Glucose Levels Enhance Entry Factor Expression and Hepatic SARS-CoV-2 Infection., PMID:40442985
Evaluation of tumor targets selected from public genomic databases for imaging of pancreatic ductal adenocarcinoma., PMID:40379788
TEAD4 promoted proliferation and metastasis of gallbladder cancer by regulation of TMPRSS4., PMID:40214821
TMPRSS4 as a prognostic biomarker after gastric cancer surgery in a multicenter retrospective study., PMID:40069485
Identification of potent TMPRSS4 inhibitors through structural modeling and molecular dynamics simulations., PMID:39838126
Unveiling the impact of C15orf48 on non-small cell lung cancer through NF-kappa B signaling., PMID:39576886
miR-149-3p targeting TMPRSS4 regulates the sensitivity to cisplatin to inhibit the progression of lung cancer., PMID:39388706
A modified model of PANoptosisto identify prognosis and immunotherapy response in bladder cancer., PMID:39368544
Prediction of the Aggressive Clinical Course of Papillary Thyroid Carcinoma Based on Fine Needle Aspiration Biopsy Molecular Testing., PMID:39000197
Knockdown of circ_0076305 decreases the paclitaxel resistance of non-small cell lung cancer cells by regulating TMPRSS4 via miR-936., PMID:38993483
TMPRSS13 promotes the cell entry of swine acute diarrhea syndrome coronavirus., PMID:38808555
Effects of transmembrane serine protease 4 on the survival in patients with pancreatic ductal adenocarcinoma undergoing surgery followed by adjuvant chemotherapy., PMID:38637344
Identification of receptors and factors associated with human coronaviruses in the oral cavity using single-cell RNA sequencing., PMID:38560173
Laminin 332 expression levels predict clinical outcomes and chemotherapy response in patients with pancreatic adenocarcinoma., PMID:37779898
Design of a novel multi-epitope vaccine candidate against endometrial cancer using immunoinformatics and bioinformatics approaches., PMID:37771176
Idiopathic Pulmonary Fibrosis Molecular Substrates Revealed by Competing Endogenous RNA Regulatory Networks., PMID:37540140
Sequencing and Bioinformatics analysis of lncRNA/circRNA-miRNA-mRNA in Glioblastoma multiforme., PMID:37389689
Honokiol inhibits epithelial-mesenchymal transition and hepatic fibrosis via activation of Ecadherin/GSK3β/JNK and inhibition of AKT/ERK/p38/β-catenin/TMPRSS4 signaling axis., PMID:37253375
Identification of Embryonic Chicken Proteases Activating Newcastle Disease Virus and Their Roles in the Pathogenicity of Virus Used as In Ovo Vaccine., PMID:37042750
SARS-CoV-2 infection aggravates cigarette smoke-exposed cell damage in primary human airway epithelia., PMID:37041586
TMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer., PMID:37009799
Data-Driven Identification of Targets for Fluorescence-Guided Surgery in Non-Small Cell Lung Cancer., PMID:36575340
The expression profile of 79 genes from 107 viruses revealed new insights into disease susceptibility in rats, mice, and muskrats., PMID:36445693
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma., PMID:36380313
Camostat mesilate, a serine protease inhibitor, exerts aquaretic effects and decreases urinary exosomal AQP2 levels., PMID:36344042
Increased TRIM31 gene expression is positively correlated with SARS-CoV-2 associated genes TMPRSS2 and TMPRSS4 in gastrointestinal cancers., PMID:35970857
Gene expression patterns associated with multidrug therapy in multibacillary leprosy., PMID:35937686
ACE inhibitors on ACE1, ACE2, and TMPRSS2 expression and spheroid attachment on human endometrial Ishikawa cells., PMID:35688117
Interaction Analysis of Adenovirus L5 Protein With Pancreatic Cancer Cell Surface Receptor to Analyze Its Affinity for Oncolytic Virus Therapy., PMID:35359382
Effect of SARS-CoV-2 Entry Factors on Myeloid Cancers., PMID:35283406
ENaC activation by proteases., PMID:35276025
Investigating underlying human immunity genes, implicated diseases and their relationship to COVID-19., PMID:35261286
Protein expression of transmembrane protease serine 4 in the gastrointestinal tract and in healthy, cancer, and SARS‑CoV‑2 infected lungs., PMID:35211765
Chromosome-Scale Genome of Masked Palm Civet (Paguma larvata) Shows Genomic Signatures of Its Biological Characteristics and Evolution., PMID:35126472
Evolutionary history of type II transmembrane serine proteases involved in viral priming., PMID:35122525
The lncRNA HOXA11-AS acts as a tumor promoter in breast cancer through regulation of the miR-125a-5p/TMPRSS4 axis., PMID:35106863
Host cell entry mediators implicated in the cellular tropism of SARS‑CoV‑2, the pathophysiology of COVID‑19 and the identification of microRNAs that can modulate the expression of these mediators (Review)., PMID:34935057
Characterization of SARS-CoV-2 Entry Factors' Expression in Corneal and Limbal Tissues of Adult Human Donors Aged from 58 to 85., PMID:34889660
TMPRSS4 promotes cancer stem-like properties in prostate cancer cells through upregulation of SOX2 by SLUG and TWIST1., PMID:34809669
Expression of SARS-CoV-2 entry factors, electrolyte, and mineral transporters in different mouse intestinal epithelial cell types., PMID:34755492
TMPRSS4 overexpression promotes the metastasis of colorectal cancer and predicts poor prognosis of stage III-IV colorectal cancer., PMID:34595980
Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19., PMID:34575910
Type II transmembrane serine proteases 4 (TMPRSS4) promotes proliferation, invasion and epithelial-mesenchymal transition in endometrial carcinoma cells (HEC1A and Ishikawa) via activation of MAPK and AKT., PMID:34408809
Utility of TMPRSS4 as a Prognostic Biomarker and Potential Therapeutic Target in Patients with Gastric Cancer., PMID:34379296
Mesalamine Reduces Intestinal ACE2 Expression Without Modifying SARS-CoV-2 Infection or Disease Severity in Mice., PMID:34373857
Single-cell RNA sequencing of SARS-CoV-2 cell entry factors in the preconceptional human endometrium., PMID:34329437
HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells., PMID:34252054
Characteristics of Angiotensin I-converting enzyme 2, type II transmembrane serine protease 2 and 4 in tree shrew indicate it as a potential animal model for SARS-CoV-2 infection., PMID:34227905
Transmembrane Protease TMPRSS4 Promotes the Formation and Development of Mismatch Repair Deficient Colon Cancer Liver Metastasis., PMID:34173918
Inhibition of TMPRSS4 mediated epithelial-mesenchymal transition is critically involved in antimetastatic effect of melatonin in colorectal cancers., PMID:34114707
For research use only. Not for human or drug use.
