Catalog No.
YHJ65201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala251-Gly364
Predicted molecular weight
15.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NR23
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GDF-3, GDF3, Growth/differentiation factor 3
Acute regulation of murine adipose tissue lipolysis and insulin resistance by the TGFβ superfamily protein GDF3., PMID:40360531
A chromatin-focused CRISPR screen identifies USP22 as a barrier to somatic cell reprogramming., PMID:40102626
Total saponins from Panax japonicus mediate the paracrine interaction between adipocytes and macrophages to promote lipolysis in the adipose tissue during aging via the NLRP3 inflammasome/GDF3/ATGL axis., PMID:39662098
Analysis of the pluripotent and germline marker gene expression, and the state of X chromosome reactivation of primordial germ cells in pig gonads., PMID:39413538
Human Genetics of Ventricular Septal Defect., PMID:38884729
[Expression and significance analysis of GDF3 in testicular cancer based on TCGA and GTEx databases]., PMID:38639949
Genetic insights into the 'sandwich fusion' subtype of Klippel-Feil syndrome: novel FGFR2 mutations identified by 21 cases of whole-exome sequencing., PMID:38561822
GDF3 Protects Mice against Sepsis-Induced Acute Lung Injury by Suppression of Macrophage Pyroptosis., PMID:38543054
Molecular mechanisms controlling the biogenesis of the TGF-β signal Vg1., PMID:37844219
A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone loss., PMID:37385982
Clinicopathological relevance of stem cell marker growth and differentiation factor 3 in esophageal squamous cell carcinoma., PMID:37205315
Obesity-Linked PPARγ Ser273 Phosphorylation Promotes Beneficial Effects on the Liver, despite Reduced Insulin Sensitivity in Mice., PMID:37189379
The GDF3-ALK7 signaling axis in adipose tissue: a possible therapeutic target for obesity and associated diabetes?, PMID:37081691
In vivo targeting and multimodal imaging of cerebral amyloid-β aggregates using hybrid GdF3 nanoparticles., PMID:36927004
Construction of a prognostic prediction model for renal clear cell carcinoma combining clinical traits., PMID:36849551
Novel Cardiokine GDF3 Predicts Adverse Fibrotic Remodeling After Myocardial Infarction., PMID:36484260
TWIST1 activates cancer stem cell marker genes to promote epithelial-mesenchymal transition and tumorigenesis in esophageal squamous cell carcinoma., PMID:36474162
A multi-omic landscape of steatosis-to-NASH progression., PMID:39872077
Signal Amplification Pretargeted PET/Fluorescence Imaging Based on Human Serum Albumin-Encapsulated GdF3 Nanoparticles for Diagnosis of Ovarian Cancer., PMID:36218278
The intrinsic and extrinsic effects of TET proteins during gastrulation., PMID:35908548
Increased Serum Levels of Growth-Differentiation Factor 3 (GDF3) and Inflammasome-Related Markers in Pregnant Women during Acute Zika Virus Infection., PMID:35632746
Secreted key regulators (Fgf1, Bmp4, Gdf3) are expressed by PAC1-immunopositive retinal ganglion cells in the postnatal rat retina., PMID:35477223
Transcriptional analysis of gasoline engine exhaust particulate matter 2.5-exposed human umbilical vein endothelial cells reveals the different gene expression patterns related to the cardiovascular diseases., PMID:34988296
Generation of an iPSC line (ZZUNEUi021-A) from a hypertrophic cardiomyopathy patient with TNNT2 mutation., PMID:34929444
Impaired Skeletal Muscle Development and Regeneration in Transglutaminase 2 Knockout Mice., PMID:34831312
Multimodal fluorescently labeled polymer-coated GdF3 nanoparticles inhibit degranulation in mast cells., PMID:34755752
Global Histone H3 Lysine 4 Trimethylation (H3K4me3) Landscape Changes in Response to TGFβ., PMID:34671716
Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5., PMID:34531379
A case for revisiting Nodal signaling in human pluripotent stem cells., PMID:33932319
Brd4 modulates diet-induced obesity via PPARγ-dependent Gdf3 expression in adipose tissue macrophages., PMID:33830083
Administration of GDF3 Into Septic Mice Improves Survival via Enhancing LXRα-Mediated Macrophage Phagocytosis., PMID:33679812
[Clinical Characteristics and Genetic Analysis of Klippel-Feil Syndrome]., PMID:33663658
Multifunctional Transferrin Encapsulated GdF3 Nanoparticles for Sentinel Lymph Node and Tumor Imaging., PMID:33155818
Long-term arsenic exposure impairs differentiation in mouse embryonal stem cells., PMID:33124703
Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3., PMID:32941798
A Multidisciplinary Review of the Roles of Cripto in the Scientific Literature Through a Bibliometric Analysis of its Biological Roles., PMID:32517087
The mutational burden and oligogenic inheritance in Klippel-Feil syndrome., PMID:32278351
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype., PMID:31947892
Derivation of notochordal cells from human embryonic stem cells reveals unique regulatory networks by single cell-transcriptomics., PMID:31840817
Effects of environmental chemicals on the proliferation and differentiation of neural stem cells., PMID:31400064
Pluripotency Potential of Embryonic Stem Cell-Like Cells Derived from Mouse Testis., PMID:31210434
Znf703 is a novel RA target in the neural plate border., PMID:31164691
mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism., PMID:30924297
Paraquat affects the differentiation of neural stem cells and impairs the function of vascular endothelial cells: a study of molecular mechanism., PMID:30698896
Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse., PMID:30446628
ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma., PMID:30401983
Phylogenetic evidence for independent origins of GDF1 and GDF3 genes in anurans and mammals., PMID:30206386
Genome editing in induced pluripotent stem cells rescues TAF1 levels in X-linked dystonia-parkinsonism., PMID:30153385
Staufen1, Kinesin1 and microtubule function in cyclin B1 mRNA transport to the animal polar cytoplasm of zebrafish oocytes., PMID:30103945
The modification of mitochondrial energy metabolism and histone of goat somatic cells under small molecules compounds induction., PMID:30098220
For research use only. Not for human or drug use.
