Catalog No.
YHJ64301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys27-Met245
Predicted molecular weight
27.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NQ66
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PLCB1, Phosphoinositide phospholipase C-beta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, KIAA0581, Phospholipase C-beta-1, Phospholipase C-I, PLC-I, PLC-154, PLC-beta-1
[Phospholipase Cβ1 (PLCB1) promotes gastric adenocarcinoma metastasis by inducing epithelial mesenchymal transition and inhibiting tumour immune infiltration and is associated with poor patient prognosis]., PMID:40415624
Transcriptome analysis of testis and epididymis identifies key genes and pathways regulating gander sperm motility., PMID:40081175
Deciphering the Role of Calcium Signaling Pathway-Associated Single Nucleotide Variants in Susceptibility to Hypertension., PMID:39817473
FOS-Mediated PLCB1 Induces Radioresistance and Weakens the Antitumor Effects of CD8+ T Cells in Triple-Negative Breast Cancer., PMID:39451071
Exploration of the shared gene signatures and molecular mechanisms between Alzheimer's disease and intracranial aneurysm., PMID:39427050
Multi-Omics Reveals the Role of Arachidonic Acid Metabolism in the Gut-Follicle Axis for the Antral Follicular Development of Holstein Cows., PMID:39273467
The identification of key molecules and pathways in the crosstalk of calcium oxalate-treated TCMK-1 cells and macrophage via exosomes., PMID:39251681
Increased oxygen stimulation promotes chemoresistance and phenotype shifting through PLCB1 in gliomas., PMID:39053384
In vivo vitamin D target genes interconnect key signaling pathways of innate immunity., PMID:39042613
Phospholipase C beta 1 in the dentate gyrus gates fear memory formation through regulation of neuronal excitability., PMID:38959322
[The diagnostic value of inflammation-related genes in bronchopulmonary dysplasia]., PMID:38955739
LncRNA AC100826.1 regulated PLCB1 to promote progression in non-small cell lung cancer., PMID:38778543
Elucidating the Role of circTIAM1 in Guangling Large-Tailed Sheep Adipocyte Proliferation and Differentiation via the miR-485-3p/PLCB1 Pathway., PMID:38731807
Single-cell RNA-seq analysis reveals the Wnt/Ca2+ signaling pathway with inflammation, apoptosis in nucleus pulposus degeneration., PMID:38654287
Lnc-PLCB1 is stabilized by METTL14 induced m6A modification and inhibits Helicobacter pylori mediated gastric cancer by destabilizing DDX21., PMID:38387756
Detection of polymorphisms in six genes and their association analysis with litter size in sheep., PMID:38294691
Identification and characterization of biomarkers associated with endoplasmic reticulum protein processing in cerebral ischemia-reperfusion injury., PMID:38188159
Genetic predisposition to differentiated thyroid cancer in the Polish population., PMID:38165228
Lipid metabolism and neuromuscular junction as common pathways underlying the genetic basis of erectile dysfunction and obstructive sleep apnea., PMID:37990110
Hidradenitis suppurativa associated telomere-methylome dysregulations in blood., PMID:37872100
Weighted single-step genome-wide association study and functional enrichment analyses for gastrointestinal nematode resistance traits in Santa Ines sheep., PMID:37857178
Illuminating (HTLV-1)-induced adult T-cell leukemia/lymphoma transcriptomic signature: A systems virology approach., PMID:37832654
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism., PMID:37500770
Study on the Key Genes and Molecular Mechanisms of IL-27 Promoting Keratinocytes Proliferation Based on Transcriptome Sequencing., PMID:37309428
PLCB1 Enhances Cell Migration and Invasion in Gastric Cancer Via Regulating Actin Cytoskeletal Remodeling and Epithelial-Mesenchymal Transition., PMID:37208557
Dodecyl creatine ester improves cognitive function and identifies key protein drivers including KIF1A and PLCB1 in a mouse model of creatine transporter deficiency., PMID:37063368
DNA methylation profiling reveals novel pathway implicated in cardiovascular diseases of diabetes., PMID:36875456
Effect of SNHG11/miR-7-5p/PLCB1 Axis on Acute Pancreatitis through Inhibiting p38MAPK Pathway., PMID:36611865
Conformational alteration in glycan induces phospholipase Cβ1 activation and angiogenesis., PMID:36517806
Differential Expression of lncRNA-miRNA-mRNA and Their Related Functional Networks in New-Onset Type 2 Diabetes Mellitus among Chinese Rural Adults., PMID:36360309
Genome-wide analysis identified candidate variants and genes associated with heat stress adaptation in Egyptian sheep breeds., PMID:36263427
Genetic parameters and genome-wide association for milk production traits and somatic cell score in different lactation stages of Shanghai Holstein population., PMID:36134029
Distinctive gene expression patterns in pregnancy-associated breast cancer., PMID:36035177
Investigation of differentially expressed genes and dysregulated pathways involved in multiple sclerosis., PMID:35871892
Comprehensive analysis of DNA methylation for periodontitis., PMID:35491409
Elevation of phospholipase C-β1 expression by amyloid-β facilitates calcium overload in neuronal cells., PMID:35469845
Transcriptome profiling of mRNAs in muscle tissue of Pinan cattle and Nanyang cattle., PMID:35301069
Orexin 1 Receptor Antagonism in the Basolateral Amygdala Shifts the Balance From Pro- to Antistress Signaling and Behavior., PMID:35279280
Identification of the shared gene signatures and pathways between sarcopenia and type 2 diabetes mellitus., PMID:35271662
Comparative transcriptome analysis identifies crucial candidate genes and pathways in the hypothalamic-pituitary-gonadal axis during external genitalia development of male geese., PMID:35168567
Targeting GNAQ in hypothalamic nerve cells to regulate seasonal estrus in sheep., PMID:35065460
Comparative analysis of protein-protein interaction networks in metastatic breast cancer., PMID:35045088
Meta-analysis of genome-wide association studies for litter size in sheep., PMID:34968818
The Mouse Cytomegalovirus G Protein-Coupled Receptor Homolog, M33, Coordinates Key Features of In Vivo Infection via Distinct Components of Its Signaling Repertoire., PMID:34878888
Carbon monoxide enhances calcium transients and glucose-stimulated insulin secretion from pancreatic β-cells by activating Phospholipase C signal pathway in diabetic mice., PMID:34678590
A PLCB1-PI3K-AKT Signaling Axis Activates EMT to Promote Cholangiocarcinoma Progression., PMID:34580062
Human embryo polarization requires PLC signaling to mediate trophectoderm specification., PMID:34569938
Reconstructing aspects of human embryogenesis with pluripotent stem cells., PMID:34548496
Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia., PMID:34301992
Investigation of high correlation with carcass traits of SNPs of the PLCB1, C/EBPα, and TDRKH genes and the combinations of SNPs using the MDR method in the Hanwoo., PMID:34129193
For research use only. Not for human or drug use.
