Catalog No.
YMJ64101
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Tyr24-Arg184
Predicted molecular weight
19.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9QYY7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ESM-1, ESM1, Endothelial cell-specific molecule 1
An endothelial specific mouse model for the capillary malformation mutation Gnaq p.R183Q., PMID:40498353
Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology., PMID:40453069
Diagnostic and Prognostic Evaluation of Novel Biomarkers Compared to ESC 0/1 h and 0/3 h Algorithms in Patients with Suspected Non-ST-Elevation Myocardial Infarction., PMID:40363990
IRF5 Mediates Artery Inflammation in Salt-Sensitive Hypertension by Regulating STAT1 and STAT2 Phosphorylation to Increase ESM1 Transcription: Insights from Bioinformatics and Mechanistic Analysis., PMID:40332339
Unveiling the protective role of ESM1 in endothelial cell proliferation and lipid reprogramming., PMID:40320451
The predictive value of endocan as a novel biomarker: an umbrella study on meta-analyses., PMID:40312748
[Predictive values of serum endocan and retinol-binding protein 4 levels for pregnancy outcomes in patients with gestational diabetes mellitus]., PMID:40289779
Serum Endocan Levels as a Risk Factor for Peripheral Artery Disease in Non-Dialysis Patients with Chronic Kidney Disease Stages 3-5., PMID:40282868
IGF2BP3/ESM1/KLF10/BECN1 positive feedback loop: a novel therapeutic target in ovarian cancer via lipid metabolism reprogramming., PMID:40240362
Biomarker and cognitive decline in atrial fibrillation: a prospective cohort study., PMID:40234472
Single-cell sequencing uncovers a high ESM1-expression endothelial cell subpopulation associated with bladder cancer progression and the immunosuppressive microenvironment., PMID:40159545
sFlt-1/PlGF ratio combined with endocan-1 serum levels improves the predictive values for the occurrence and prognosis of preeclampsia in a single centre study., PMID:40133446
Correlation analysis of serum endothelial cell specific molecule-1, endothelial microparticles, hypoxia inducible factor-1α levels and acute myocardial infarction and their predictive value for major adverse cardiovascular events: a retrospective study., PMID:40124612
The relationship between serum Endocan and ADMA levels and penile Doppler ultrasonography findings in patients with severe erectile dysfunction., PMID:40101085
ESM1 suppresses LncRNA GAS5/miR-23a-3p/PTEN axis to promote the cisplatin-chemotherapy resistance of ovarian cancer cells via activating the PI3K/AKT pathway., PMID:40089962
ESM-1 Promotes the Process of Diabetic Nephropathy by Promoting the Expression of CXCL3., PMID:40045860
ESM-1 and GBP-1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?, PMID:40042932
Serum Soluble Endocan Might Be a Predictor of Preterm Labor., PMID:40019117
ESM1 promote proliferation, invasion and angiogenesis via Akt/mTOR and Ras pathway in kidney renal clear cell carcinoma., PMID:39929852
Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes., PMID:39915484
Endocan as a marker of endotheliitis in COVID-19 patients: modulation by veno-venous extracorporeal membrane oxygenation, arterial hypertension and previous treatment with renin-angiotensin-aldosterone system inhibitors., PMID:39862311
Endothelial-secreted Endocan activates PDGFRA and regulates vascularity and spatial phenotype in glioblastoma., PMID:39773984
Olink Profiling of Intestinal Tissue Identifies Novel Biomarkers For Colorectal Cancer., PMID:39757570
Endocan expression and correlation with other endothelial determinants in developing a score for early identification of diabetic peripheral neuropathy., PMID:39757242
[GSK484, a PAD4 inhibitor, improves endothelial dysfunction in mice with sepsis-induced lung injury by inhibiting H3Cit expression]., PMID:39725629
Association between serum endocan levels and organ failure in hospitalized patients with cirrhosis., PMID:39724169
Association of plasma endocan levels with metabolic parameters and predictive value of endocan for the development of complications in patients with type 2 diabetes mellitus: An observational study., PMID:39720951
Levothyroxine therapy reduces endocan and total cholesterol concentrations in patients with subclinical hypothyroidism., PMID:39703763
Human adenovirus type 7 (HAdV-7) infection induces pulmonary vascular endothelial injury through the activation of endothelial autophagy., PMID:39633448
Relation of Endocan Serum Levels with Patient Characteristics and Morphological Features of Uterine Fibroids: A Case-Control Study., PMID:39561723
Serum endocan (ESM-1) as diagnostic and prognostic biomarker in Multisystem inflammatory syndrome in children (MIS-C)., PMID:39488191
Biochemical markers and carotid intima-media thickness in relation to cardiovascular risk in young women., PMID:39433538
The Relationship between Vascular Biomarkers (Serum Endocan and Endothelin-1), NT-proBNP, and Renal Function in Chronic Kidney Disease, IgA Nephropathy: A Cross-Sectional Study., PMID:39408883
Serum Endocan Levels in Children with Acute Rheumatic Fever., PMID:39348324
Blood endocan as a biomarker for breast cancer recurrence., PMID:39331092
Endocan, a novel glycoprotein with multiple biological activities, may play important roles in neurological diseases., PMID:39328246
ESM1 facilitates the EGFR/HER3-triggered epithelial-to-mesenchymal transition and progression of gastric cancer via modulating interplay between Akt and angiopoietin-2 signaling., PMID:39309430
BMP10 reflects pre-capillary pulmonary hemodynamics: association of biomarkers and hemodynamic parameters in pulmonary hypertension., PMID:39297942
The role of ESM1 in the lipids metabolic reprogramming and angiogenesis of lung adenocarcinoma cells., PMID:39281564
The effect of supplemental oxygen and continuous positive airway pressure withdrawal on endocan levels., PMID:39240486
Endocan may predict the presence of coronary slow flow and coronary artery disease., PMID:39230149
Machine learning approach to predict blood-secretory proteins and potential biomarkers for liver cancer using omics data., PMID:39216516
Conventional and Novel Inflammatory Biomarkers in Chronic Heart Failure Patients with Atrial Fibrillation., PMID:39202519
Endothelial cell heterogeneity in colorectal cancer: tip cells drive angiogenesis., PMID:39172168
Construction of an IFNAR1 knockout MDBK cell line using CRISPR/Cas9 and its effect on bovine virus replication., PMID:39100665
Recombinant human thrombopoietin in alleviating endothelial cell injury in sepsis., PMID:39035616
Human ARMC6 binds in vitro to both cancer genes and telomeric RNA, favoring G-quadruplex structure recognition., PMID:39029558
Histone lactylation facilitates hepatocellular carcinoma progression by upregulating endothelial cell-specific molecule 1 expression., PMID:39016629
Relationship between angiogenesis biomarker endocan and apolipoproteins in patients with acute myocardial infarction., PMID:38967435
Endothelial cell specific molecule 1 promotes epithelial-mesenchymal transition of cervical cancer via the E-box binding homeobox 1., PMID:38954708
For research use only. Not for human or drug use.
