Catalog No.
YHJ62601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr108-Ile313
Predicted molecular weight
25.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NPA2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Membrane-type matrix metalloproteinase 6, MMP-25, MT6MMP, MMPL1, MT-MMP 6, MTMMP6, Membrane-type-6 matrix metalloproteinase, MT6-MMP, Matrix metalloproteinase-25, Leukolysin, MMP25, MMP20
Modulation of the malignant behavior of tongue squamous cell carcinoma cells by matrix metallopeptidase 25 through the NF-κB pathway., PMID:39668749
RNA-binding proteins potentially regulate alternative splicing of immune/inflammatory-associated genes during the progression of generalized pustular psoriasis., PMID:39158708
Identification of DLEU2 as biomarker based on lncRNA-Mediated ceRNA network in rupture of intracranial aneurysm., PMID:38650140
A brain-specific angiogenic mechanism enabled by tip cell specialization., PMID:38570687
Transcriptomic analysis delineates preterm prelabor rupture of membranes from preterm labor in preterm fetal membranes., PMID:38443884
Single-Cell Transcriptome Reveals Potential Mechanisms for Coronary Artery Lesions in Kawasaki Disease., PMID:38357816
Elevated Plasma Levels of MT4-MMP and MT6-MMP; A New Observation in Patients with Thyroid Nodules., PMID:38310435
Association of MMP3, MMP14, and MMP25 gene polymorphisms with cerebral stroke risk: a case-control study., PMID:37986083
Cannabinoid enhancement of lncRNA MMP25-AS1/MMP25 interaction reduces neutrophil infiltration and intestinal epithelial injury in HIV/SIV infection., PMID:37036007
Urinary endogenous peptides as biomarkers for prostate cancer., PMID:36970608
Identification of the MMP family as therapeutic targets and prognostic biomarkers in the microenvironment of head and neck squamous cell carcinoma., PMID:36941602
Identification of the Immune Subtypes for the Prediction of Metastasis in Pancreatic Neuroendocrine Tumors., PMID:36871552
Immune cell-specific smoking-related expression characteristics are revealed by re-analysis of transcriptomes from the CEDAR cohort., PMID:36817262
Pre-Activated Granulocytes from an Autoimmune Uveitis Model Show Divergent Pathway Activation Profiles upon IL8 Stimulation In Vitro., PMID:36076947
Landscape Analysis of Matrix Metalloproteinases Unveils Key Prognostic Markers for Patients With Breast Cancer., PMID:35069702
Matrix metalloproteinase-25 from Japanese sea bass (Lateolabrax japonicus) is involved in pro-inflammatory responses., PMID:35026231
Integrated Gene Expression Profiling Analysis Reveals Potential Molecular Mechanisms and Candidate Biomarkers for Early Risk Stratification and Prediction of STEMI and Post-STEMI Heart Failure Patients., PMID:34957234
Determination of tipping point in course of PM2.5 organic extracts-induced malignant transformation by dynamic network biomarkers., PMID:34933256
A novel lncRNA-miRNA-mRNA competing endogenous RNA regulatory network in lung adenocarcinoma and kidney renal papillary cell carcinoma., PMID:34453499
Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis., PMID:33469142
Activity and components of the granulocyte colony-stimulating factor pathway in hidradenitis suppurativa., PMID:33400270
Matrix metalloproteinase-7, -8, -9, -15, and -25 in minor salivary gland adenoid cystic carcinoma., PMID:33278774
Elevated S100A9 expression in chronic rhinosinusitis coincides with elevated MMP production and proliferation in vitro., PMID:33005006
Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms., PMID:31779701
The prognostic values of matrix metalloproteinases in ovarian cancer., PMID:31099295
Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion., PMID:30904617
Embedding of Genes Using Cancer Gene Expression Data: Biological Relevance and Potential Application on Biomarker Discovery., PMID:30662451
The Expression of Matrix Metalloproteinases in Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL)-expressing Cancer of Apocrine Origin., PMID:29277763
Human eosinophils constitutively express a unique serine protease, PRSS33., PMID:28216055
Matrix metalloproteinases as reagents for cell isolation., PMID:27702483
Genome-wide analysis identifies differential promoter methylation of Leprel2, Foxf1, Mmp25, Igfbp6, and Peg12 in murine tendinopathy., PMID:27517731
MMP-25 Metalloprotease Regulates Innate Immune Response through NF-κB Signaling., PMID:27259858
Olig2 is expressed late in human eosinophil development and controls Siglec-8 expression., PMID:27154355
Proteinases and plaque rupture: unblocking the road to translation., PMID:25089553
Mmp25β facilitates elongation of sensory neurons during zebrafish development., PMID:25074687
Ovarian membrane-type matrix metalloproteinases: induction of MMP14 and MMP16 during the periovulatory period in the rat, macaque, and human., PMID:24920038
Expression of the matrix metalloproteases 2, 14, 24, and 25 and tissue inhibitor 3 as potential molecular markers in advanced human gastric cancer., PMID:24669030
Matrix metalloproteinase-7 and matrix metalloproteinase-25 in oral tongue squamous cell carcinoma., PMID:24488688
MMP-7 and TIMP-1, new targets in predicting poor wound healing in apical periodontitis., PMID:23953287
Serum biomarkers in elderly asthma., PMID:23952480
Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells., PMID:23851692
MT-MMPs in pre-eclamptic placenta: relationship to soluble endoglin production., PMID:23261267
Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-κB., PMID:22880008
Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophage phagocytic activities., PMID:22367194
Effect of sulindac sulfide on metallohydrolases in the human colon cancer cell line HT-29., PMID:21991341
Matrix metalloproteinase 14 and 19 expression is associated with thoracic aortic aneurysms., PMID:21955474
Pericellular proteins of the developing mouse tendon: a proteomic analysis., PMID:21851252
Genome-wide identification of possible methylation markers chemosensitive to targeted regimens in colorectal cancers., PMID:21850381
Matrix metalloproteinase proteolysis of the mycobacterial HSP65 protein as a potential source of immunogenic peptides in human tuberculosis., PMID:21752195
Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors., PMID:21514700
For research use only. Not for human or drug use.
