Catalog No.
YHJ61201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn844-Asp1096
Predicted molecular weight
31.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HD43
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
R-PTP-H, SAP1, PTPRH, Receptor-type tyrosine-protein phosphatase H, SAP-1, Stomach cancer-associated protein tyrosine phosphatase 1, Transmembrane-type protein-tyrosine phosphatase type H
The impaired response of nasal epithelial cells to microplastic stimulation in asthma and COPD., PMID:39905077
Increased intestinal permeability and lipopolysaccharide contribute to swainsonine-induced systemic inflammation., PMID:39181073
PTPRH promotes the progression of non-small cell lung cancer via glycolysis mediated by the PI3K/AKT/mTOR signaling pathway., PMID:37974250
Establishment of a Lymph Node Metastasis-Associated Prognostic Signature for Lung Adenocarcinoma., PMID:36793937
Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH., PMID:36054194
Crystal structure of the catalytic domain of human RPTPH., PMID:35787553
Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors., PMID:35685361
Allele-specific expression reveals genes with recurrent cis-regulatory alterations in high-risk neuroblastoma., PMID:35246212
The Protein Landscape of Mucinous Ovarian Cancer: Towards a Theranostic., PMID:34830751
The High Expression of PTPRH Is Associated with Poor Prognosis of Human Lung Adenocarcinoma., PMID:34367321
Mutations of METTL3 predict response to neoadjuvant chemotherapy in muscle-invasive bladder cancer., PMID:34239995
CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP., PMID:34187934
Identification of novel regulators of STAT3 activity., PMID:32231398
Biological function of protein tyrosine phosphatase H-type receptor and its progress in tumor., PMID:32132299
Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma., PMID:31837707
Integrated analyses of murine breast cancer models reveal critical parallels with human disease., PMID:31332182
Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Regulates Retinal Axonal Projections by Inhibiting Eph and Abl Kinases in Mice., PMID:30082414
Downregulation of PTPRH (Sap-1) in colorectal tumors., PMID:28713969
Phosphotyrosine phosphatase R3 receptors: Origin, evolution and structural diversification., PMID:28257417
Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing., PMID:28137300
A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome., PMID:28065597
Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium., PMID:26195794
Prognostic implication of PTPRH hypomethylation in non-small cell lung cancer., PMID:26134684
The R3 receptor-like protein tyrosine phosphatase subfamily inhibits insulin signalling by dephosphorylating the insulin receptor at specific sites., PMID:26063811
Fine specificity and molecular competition in SLAM family receptor signalling., PMID:24642916
To the genesis of Burkitt lymphoma: regulation of apoptosis by EBNA-1 and SAP may determine the fate of Ig-myc translocation carrying B lymphocytes., PMID:19874894
SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis., PMID:19170756
Sap-1/PTPRH activity is regulated by reversible dimerization., PMID:15850787
Mapping of a translocation breakpoint in a Peutz-Jeghers hamartoma to the putative PJS locus at 19q13.4 and mutation analysis of candidate genes in polyp and STK11-negative PJS cases., PMID:15287029
Downregulation of stomach cancer-associated protein tyrosine phosphatase-1 (SAP-1) in advanced human hepatocellular carcinoma., PMID:12879010
Interaction of SAP-1, a transmembrane-type protein-tyrosine phosphatase, with the tyrosine kinase Lck. Roles in regulation of T cell function., PMID:12837766
Cloning of two new splice variants of Siglec-10 and mapping of the interaction between Siglec-10 and SHP-1., PMID:12163025
Induction of apoptosis by stomach cancer-associated protein-tyrosine phosphatase-1., PMID:12101188
Gene for the human transmembrane-type protein tyrosine phosphatase H (PTPRH): genomic structure, fine-mapping and its exclusion as a candidate for Peutz-Jeghers syndrome., PMID:11435690
Inhibition of cell growth and spreading by stomach cancer-associated protein-tyrosine phosphatase-1 (SAP-1) through dephosphorylation of p130cas., PMID:11278335
Overexpression of SAP-1, a transmembrane-type protein tyrosine phosphatase, in human colorectal cancers., PMID:9070877
Molecular cloning of a human transmembrane-type protein tyrosine phosphatase and its expression in gastrointestinal cancers., PMID:8294459
For research use only. Not for human or drug use.
