Catalog No.
YHJ60201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg209
Predicted molecular weight
25.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HBZ2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BHLHE1, Class E basic helix-loop-helix protein 1, Aryl hydrocarbon receptor nuclear translocator 2, KIAA0307, ARNT protein 2, ARNT2, bHLHe1
Pan-cancer analysis of ARNT2 and its oncogenic role in cervical cancer., PMID:40488594
Medulloblastoma's master regulators and their association with patients' risk., PMID:40348787
Identification of transcription factors associated with the disease-free survival of triple-negative breast cancer through weighted gene co-expression network analysis., PMID:39917004
ARNT2 controls prefrontal somatostatin interneurons mediating affective empathy., PMID:39180750
Investigation of Molecular Mechanisms of S-1, Docetaxel and Cisplatin in Gastric Cancer with a History of Helicobacter Pylori Infection., PMID:38273052
Effects of exposure to 3,6-DBCZ on neurotoxicity and AhR pathway during early life stages of zebrafish (Danio rerio)., PMID:38157798
Functional characterization of common carp (Cyprinus carpio) AHRs: Subform-specific sensitivity to dioxin and interspecies differences., PMID:37127157
Hemato-vascular specification requires arnt1 and arnt2 genes in zebrafish embryos., PMID:37039097
Integrated whole transcriptome analysis for the crucial regulators and functional pathways related to cardiac fibrosis in rats., PMID:36896551
Overexpression of POU3F2 promotes radioresistance in triple-negative breast cancer via Akt pathway activation., PMID:36797433
Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family., PMID:36343253
Potential Molecular Mechanism of Upregulated Aryl Hydrocarbon Receptor Nuclear Translocator 2 in Nasopharyngeal Carcinoma., PMID:36203533
Efficient Cas9-based Genome Editing Using CRISPR Analysis Webtools in Severe Early-onset-obesity Patient-derived iPSCs., PMID:35950852
Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons., PMID:35890127
Aryl hydrocarbon receptor is a prognostic biomarker and is correlated with immune responses in cervical cancer., PMID:34784845
Stuttering: A Disorder of Energy Supply to Neurons?, PMID:34630054
Exosomal transfer of miR-106a-5p contributes to cisplatin resistance and tumorigenesis in nasopharyngeal carcinoma., PMID:34469038
Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity., PMID:34214899
Elevation of DNA Methylation in the Promoter Regions of the Brain-Derived Neurotrophic Factor Gene is Associated with Heroin Addiction., PMID:34173192
DNA Copy Number Variation Associated with Anti-tumour Necrosis Factor Drug Response and Paradoxical Psoriasiform Reactions in Patients with Moderate-to-severe Psoriasis., PMID:33846759
The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease Development., PMID:33799876
Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders., PMID:33758288
Impairment of the Hif-1α regulatory pathway in Foxn1-deficient (Foxn1-/- ) mice affects the skin wound healing process., PMID:33475195
Identifying age-specific gene signatures of the human cerebral cortex with joint analysis of transcriptomes and functional connectomes., PMID:33367491
G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor β2 in the rat hypothalamic paraventricular nucleus., PMID:33201916
The AHR1-ARNT1 dimerization pair is a major regulator of the response to natural ligands, but not to TCDD, in the chicken., PMID:32563159
Oligodendrocyte ARNT2 expression is altered in models of MS., PMID:32439712
Aryl hydrocarbon receptor nuclear translocators (ARNT1, ARNT2, and ARNT3) of white sturgeon (Acipenser transmontanus): Sequences, tissue-specific expressions, and response to β-naphthoflavone., PMID:32081761
Polymorphisms within the ARNT2 and CX3CR1 Genes Are Associated with the Risk of Developing Invasive Aspergillosis., PMID:31964743
Functional Analysis of the SIM1 Variant p.G715V in 2 Patients With Obesity., PMID:31872862
Genomic Decoding of Neuronal Depolarization by Stimulus-Specific NPAS4 Heterodimers., PMID:31585079
Upregulation of aryl hydrocarbon receptor nuclear translocator 2 in the hippocampi of post-stroke depression rats., PMID:31338190
Effects of dietary supplementation of three strains of Lactococcus lactis on HIFs genes family expression of the common carp following Aeromonas hydrophila infection., PMID:31252044
The Yin and Yang of Arnt2 in Activity-Dependent Transcription., PMID:30998895
ARNT2 Tunes Activity-Dependent Gene Expression through NCoR2-Mediated Repression and NPAS4-Mediated Activation., PMID:30846309
Fine Particulate Matter (PM₂5) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway., PMID:30596563
A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis., PMID:30563851
Molecular cloning and characterization of two ARNT (ARNT-1 and ARNT-2) genes in Atlantic croaker and their expression during coexposure to hypoxia and PCB77., PMID:30334616
Fine Particulate Matter (PM2.5) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway., PMID:30305224
Expression of the neuroprotective protein aryl hydrocarbon receptor nuclear translocator 2 correlates with neuronal stress and disability in models of multiple sclerosis., PMID:30231889
Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia., PMID:30135684
H3K27 acetylation and gene expression analysis reveals differences in placental chromatin activity in fetal growth restriction., PMID:29983832
Overexpression of ARNT2 is associated with decreased cell proliferation and better prognosis in gastric cancer., PMID:29948506
Emotion recognition associated with polymorphism in oxytocinergic pathway gene ARNT2., PMID:29194499
Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness., PMID:29149419
Gene expression profiling of the Notch-AhR-IL22 axis at homeostasis and in response to tissue injury., PMID:29054964
Hepatoprotective and antioxidant effects of dietary Glycyrrhiza polysaccharide against TCDD-induced hepatic injury and RT-PCR quantification of AHR2, ARNT2, CYP1A mRNA in Jian Carp (Cyprinus carpio var. Jian)., PMID:28115129
[Role of hypoxia-inducible factor in the pathogenesis of rheumatoid arthritis]., PMID:27987521
Classical and non-classical causes of GH deficiency in the paediatric age., PMID:27974186
Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages., PMID:27558590