Catalog No.
YHJ58101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe166-Gly348
Predicted molecular weight
23.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H8V3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein ECT2, Epithelial cell-transforming sequence 2 oncogene, ECT2
Association of RhoGEF Ect2 with Desmoplakin Supports RhoA Activity at Intercellular Junctions: Implications for Carvajal Disease., PMID:40475587
A minimal mathematical model for polarity establishment and centralspindlin-independent cytokinesis., PMID:40341916
Based exploration of the diagnostic value of oxidative stress-related key genes in chronic obstructive pulmonary disease., PMID:40214820
Rapid and robust generation of cardiomyocyte-specific crispants in zebrafish using the cardiodeleter system., PMID:40132543
Induced Cytokinesis Generates Highly Proliferative Mononuclear Cardiomyocytes at the Expense of Contractility., PMID:39912233
Impact of m6A modification and transcript quantity on mRNA composition in plant stress granules under hypoxia., PMID:39907439
The Expression Regulation and Cancer-Promoting Roles of RACGAP1., PMID:39858398
Optimization of methods for rapid and robust generation of cardiomyocyte-specific crispants in zebrafish using the cardiodeleter system., PMID:39651137
ALBA proteins facilitate cytoplasmic YTHDF-mediated reading of m6A in Arabidopsis., PMID:39613967
The CYK-4 GAP domain regulates cortical targeting of centralspindlin to promote contractile ring assembly and facilitate ring dissolution., PMID:39554051
Identification of hub genes and pathways in Uterine corpus endometrial carcinoma (UCEC): A comprehensive in silico study., PMID:39552710
Contribution of ECT2 to Tubulointerstitial Fibrosis in the Progression of Chronic Kidney Disease., PMID:39460889
The impact of tangeretin combined with whey protein on exercise-induced bronchoconstriction in professional athletes: a placebo-controlled trial., PMID:39422600
SOXC Enhances NGN2-Mediated Reprogramming of Glioblastoma Cells Into Neuron-Like Cells by Modulating RhoA and RAC1/CDC42 Pathway Activity., PMID:39390804
ECT2 peptide sequences outside the YTH domain regulate its m6A-RNA binding., PMID:39267376
m6A modification plays an integral role in mRNA stability and translation during pattern-triggered immunity., PMID:39116132
Integrating bioinformatics and machine learning methods to analyze diagnostic biomarkers for HBV-induced hepatocellular carcinoma., PMID:39095799
Selective recognition of PTRE1 transcripts mediated by protein-protein interaction between the m6A reader ECT2 and PTRE1., PMID:39091029
Elevated expression of ECT2 as a diagnostic marker and prognostic indicator in endometrial cancer., PMID:38977110
A novel role of AURKA kinase in erythroblast enucleation., PMID:38961734
Dissecting Crucial Gene Markers Involved in HPV-Associated Oropharyngeal Squamous Cell Carcinoma from RNA-Sequencing Data through Explainable Artificial Intelligence., PMID:38940026
Discovery and validation of combined biomarkers for the diagnosis of esophageal intraepithelial neoplasia and esophageal squamous cell carcinoma., PMID:38925350
Change in RhoGAP and RhoGEF availability drives transitions in cortical patterning and excitability in Drosophila., PMID:38688282
The Molecular Characteristics and Therapeutic Implications of O-Glycan Synthesis in Pancreatic Cancer by Integrating Transcriptome and Single-Cell Data., PMID:38659264
Identification and Verification of Metabolism-related Immunotherapy Features and Prognosis in Lung Adenocarcinoma., PMID:38500277
Dbl family RhoGEFs in cancer: different roles and targeting strategies., PMID:38499108
GINS2 regulates temozolomide chemosensitivity via the EGR1/ECT2 axis in gliomas., PMID:38467631
The gene expression of CALD1, CDH2, and POSTN in fibroblast are related to idiopathic pulmonary fibrosis., PMID:38370408
Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion., PMID:38260442
Genome-wide DNA methylation of lesional and peri-lesional skin in vitiligo: a comparative and integrated analysis of multi-omics in Chinese population., PMID:38182908
Identifying hub genes and dysregulated pathways in Duchenne muscular dystrophy., PMID:38179963
A YTHDF-PABP interaction is required for m6 A-mediated organogenesis in plants., PMID:38009565
TEAD Inhibition Overcomes YAP1/TAZ-Driven Primary and Acquired Resistance to KRASG12C Inhibitors., PMID:37934103
Advanced stage, high-grade primary tumor ovarian cancer: a multi-omics dissection and biomarker prediction process., PMID:37828118
Insights into the conservation and diversification of the molecular functions of YTHDF proteins., PMID:37816028
Phosphotyrosine proteomics in cells synchronized at monopolar cytokinesis reveals EphA2 as functioning in cytokinesis., PMID:37726045
Amorphous silica nanoparticles cause abnormal cytokinesis and multinucleation through dysfunction of the centralspindlin complex and microfilaments., PMID:37608338
Multi-omics analyses based on genes associated with oxidative stress and phospholipid metabolism revealed the intrinsic molecular characteristics of pancreatic cancer., PMID:37604837
YAP co-localizes with the mitotic spindle and midbody to safeguard mitotic division in lung-cancer cells., PMID:37549045
Evolution of the triplet BRCT domain., PMID:37453244
Plant YTHDF proteins are direct effectors of antiviral immunity against an N6-methyladenosine-containing RNA virus., PMID:37431920
Screening of four signature genes for clinical testing through bioinformatics and in vitro methods in head and neck squamous cell carcinoma., PMID:37293145
Copy number variations and protein expression of Cyclin E1 and Epithelial cell transforming sequence 2 genes predict the chemotherapeutic response in patients with serous ovarian carcinoma., PMID:37250533
m6A readers ECT2/ECT3/ECT4 enhance mRNA stability through direct recruitment of the poly(A) binding proteins in Arabidopsis., PMID:37122016
Integration of Chemoinformatics and Multi-Omics Analysis Defines ECT2 as a Potential Target for Cancer Drug Therapy., PMID:37106813
Transcriptomic analysis of esophageal cancer reveals hub genes and networks involved in cancer progression., PMID:37075603
Distinct protein kinase C isoforms drive the cell cycle re-entry of two separate populations of neonatal rat ventricular cardiomyocytes., PMID:36745530
Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement., PMID:36630496
Long noncoding RNA MAPKAPK5-AS1 promotes metastasis through regulation miR-376b-5p/ECT2 axis in hepatocellular carcinoma., PMID:36567178
Significance of Identifying Key Genes Involved in HBV-Related Hepatocellular Carcinoma for Primary Care Surveillance of Patients with Cirrhosis., PMID:36553600
For research use only. Not for human or drug use.
