Catalog No.
YHJ58001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln23-Val188
Predicted molecular weight
20.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H8L6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EMILIN-3, Elastin microfibril interfacer 3, MMRN2, Elastin microfibril interface located protein 3, EndoGlyx-1 p125/p140 subunit, Multimerin-2, EMILIN3
Acute mountain sickness prediction: a concerto of multidimensional phenotypic data and machine learning strategies in the framework of predictive, preventive, and personalized medicine., PMID:40438497
Type-H endothelial cell protein Clec14a orchestrates osteoblast activity during trabecular bone formation and patterning., PMID:39394430
CD93 regulates breast cancer growth and vasculogenic mimicry through the PI3K/AKT/SP2 signaling pathway activated by integrin β1., PMID:38511888
The CXCR4/miR-1910-5p/MMRN2 Axis Is Involved in Corneal Neovascularization by Affecting Vascular Permeability., PMID:37040097
Bioinformatics Approaches to Predict Mutation Effects in the Binding Site of the Proangiogenic Molecule CD93., PMID:36353214
Comprehensive analysis of tissue proteomics in patients with papillary thyroid microcarcinoma uncovers the underlying mechanism of lymph node metastasis and its significant sex disparities., PMID:36106120
Fibroblast expression of CD248 may contribute to exacerbation of microvascular damage during systemic sclerosis., PMID:35916713
Assessment of angiogenesis-related parameters in juvenile idiopathic arthritis-associated uveitis., PMID:35359237
Characterization of the proteome and metabolome of human liver sinusoidal endothelial-like cells derived from induced pluripotent stem cells., PMID:34229994
Multi-omics analysis of tumor angiogenesis characteristics and potential epigenetic regulation mechanisms in renal clear cell carcinoma., PMID:33761933
The Binding of CD93 to Multimerin-2 Promotes Choroidal Neovascularization., PMID:32697305
CD93 negatively regulates astrogenesis in response to MMRN2 through the transcriptional repressor ZFP503 in the developing brain., PMID:32291340
Multimerin-2 maintains vascular stability and permeability., PMID:31422156
CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis., PMID:29763414
Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium., PMID:28912033
Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface., PMID:28671670
The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis., PMID:28435016
Sprouting angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid-like 2 protein (RHBDL2)., PMID:26939791
Proteomic Analysis of Urine to Identify Breast Cancer Biomarker Candidates Using a Label-Free LC-MS/MS Approach., PMID:26544852
Novel endogenous angiogenesis inhibitors and their therapeutic potential., PMID:26364800
Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth., PMID:25745997
SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers., PMID:23979707
MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway., PMID:22020326
Deletion of multimerin-1 in alpha-synuclein-deficient mice., PMID:15177571
For research use only. Not for human or drug use.
