Catalog No.
YHJ56701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys309
Predicted molecular weight
37.48 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H479
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein-ribulosamine 3-kinase FN3K, Protein-psicosamine 3-kinase FN3K, FN3K, Fructosamine-3-kinase
Exploring the genomic and transcriptomic profiles of glycemic traits and drug repurposing., PMID:40399988
FN3K: the (un)sweetest kinase., PMID:40187910
Are polymorphisms within the fructosamine-3-kinase gene associated with the discordance between HbA1c and other measures of glycaemia?, PMID:40183993
A microscopy-based screen identifies cellular kinases modulating mitochondrial translation., PMID:39932185
The molecular basis of Human FN3K mediated phosphorylation of glycated substrates., PMID:39843453
Structural basis for FN3K-mediated protein deglycation., PMID:39173621
The molecular basis of Human FN3K mediated phosphorylation of glycated substrate., PMID:39149269
Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma., PMID:38868177
Multi-omics reveals new links between Fructosamine-3-Kinase (FN3K) and core metabolic pathways., PMID:38830903
Illuminating the functions of the understudied Fructosamine-3-kinase (FN3K) using a multi-omics approach reveals new links to lipid, carbon, and co-factor metabolic pathways., PMID:38410452
The metabolism and transformation of casein-bound lactulosyllysine in vivo: Promoting dicarbonyl stress and the formation of advanced glycation end products accompanied by systemic inflammation., PMID:38335684
Screening fructosamine-3-kinase (FN3K) inhibitors, a deglycating enzyme of oncogenic Nrf2: Human FN3K homology modelling, docking and molecular dynamics simulations., PMID:37910519
Combinatorial Implications of Nrf2 Inhibitors with FN3K Inhibitor: In vitro Breast Cancer Study., PMID:37861038
Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation Spectroscopy., PMID:35487399
Evaluation of Fructosamine 3-kinase and Glyoxalase 1 activity in normal and breast cancer tissues., PMID:35223406
A Hypothesis: Fructosamine-3-Kinase-Related-Protein (FN3KRP) Catalyzes Deglycation of Maillard Intermediates Directly Downstream from Fructosamines., PMID:34314247
A Potential Role for Fructosamine-3-Kinase in Cataract Treatment., PMID:33917258
NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy., PMID:33562682
The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers., PMID:33466626
FN3K expression in COPD: a potential comorbidity factor for cardiovascular disease., PMID:33208304
Quantitative proteomics reveals the regulatory networks of circular RNA BTBD7_hsa_circ_0000563 in human coronary artery., PMID:32710445
A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily., PMID:32636308
Role of fructosamine-3-kinase in protecting against the onset of microvascular and macrovascular complications in patients with T2DM., PMID:32467223
An Azidoribose Probe to Track Ketoamine Adducts in Histone Ribose Glycation., PMID:32390412
Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program., PMID:31564435
The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase., PMID:31398338
A multifaceted small RNA modulates gene expression upon glucose limitation in Staphylococcus aureus., PMID:30760492
Accumulation of glycated proteins suggesting premature ageing in lamin B receptor deficient mice., PMID:29081010
Evidence That Differences in Fructosamine-3-Kinase Activity May Be Associated With the Glycation Gap in Human Diabetes., PMID:29066600
Enzymatic kinetics regarding reversible metabolism of CS-0777, a sphingosine 1-phosphate receptor modulator, via phosphorylation and dephosphorylation in humans., PMID:28287856
The association between fructosamine-3 kinase 900C/G polymorphism, transferrin polymorphism and human herpesvirus-8 infection in diabetics living in South Kivu., PMID:27461879
A simple colorimetric assay for measuring fructosamine 3 kinase activity., PMID:27394048
The presence of fructosamine in human aortic valves is associated with valve stiffness., PMID:26850632
Possible role of fructosamine 3-kinase genotyping for the management of diabetic patients., PMID:26352355
Differential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells., PMID:24983248
Fructosamine 3-kinase and glyoxalase I polymorphisms and their association with soluble RAGE and adhesion molecules in diabetes., PMID:24908234
Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians., PMID:24647736
Glycated albumin and diabetes mellitus., PMID:23673238
A new HPLC-based assay for the measurement of fructosamine-3-kinase (FN3K) and FN3K-related protein activity in human erythrocytes., PMID:23648633
Detection of oxidized and glycated proteins in clinical samples using mass spectrometry--a user's perspective., PMID:23558060
Genetic variability in enzymes of metabolic pathways conferring protection against non-enzymatic glycation versus diabetes-related morbidity and mortality., PMID:23492569
Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III)., PMID:22540250
The physiological substrates of fructosamine-3-kinase-related-protein (FN3KRP) are intermediates of nonenzymatic reactions between biological amines and ketose sugars (fructation products)., PMID:21924559
Purification and identification of activating enzymes of CS-0777, a selective sphingosine 1-phosphate receptor 1 modulator, in erythrocytes., PMID:21613209
Identification of a gene-expression signature for predicting lymph node metastasis in patients with early stage cervical carcinoma., PMID:21319141
Genetic variability of the fructosamine 3-kinase gene in diabetic patients., PMID:21288167
Reduced fructosamine-3-kinase activity and its mRNA in human distal colorectal carcinoma., PMID:21052529
Enzymatic repair of Amadori products., PMID:20967558
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways., PMID:20858683
Influence of the interaction between nodal fibroblast and breast cancer cells on gene expression., PMID:20820980
For research use only. Not for human or drug use.
