Catalog No.
YHJ56601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Met247
Predicted molecular weight
30.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H3R5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CENP-H, ICEN35, Centromere protein H, CENPH, Interphase centromere complex protein 35
CENP-H as a new prognostic biomarker for tumors: a real-world literature review., PMID:40071086
TFRC-RNA interactions show the regulation of gene expression and alternative splicing associated with IgAN in human renal tubule mesangial cells., PMID:37547464
CENPH overexpression promotes the progression, cisplatin resistance, and poor prognosis of lung adenocarcinoma via the AKT and ERK/P38 pathways., PMID:37293159
Bioinformatic analysis highlights SNHG6 as a putative prognostic biomarker for kidney renal papillary cell carcinoma., PMID:37004005
A five-gene expression signature of centromeric proteins with prognostic value in lung adenocarcinoma., PMID:36915596
The predictive value of plasma exosomal lncRNAs/mRNAs in NSCLC patients receiving immunotherapy., PMID:36801676
Mobility of kinetochore proteins measured by FRAP analysis in living cells., PMID:34997387
Prognostic model of lung adenocarcinoma constructed by the CENPA complex genes is closely related to immune infiltration., PMID:34798483
Microarray Data Mining and Preliminary Bioinformatics Analysis of Hepatitis D Virus-Associated Hepatocellular Carcinoma., PMID:33564675
Impact of genetic polymorphisms in kinetochore and spindle assembly genes on chromosomal aberration frequency in healthy humans., PMID:33198934
Structural insights into the intramolecular interactions of centromere protein CENP-I., PMID:32017295
Lung adenocarcinoma pathology stages related gene identification., PMID:31731374
Identification of Prognostic Biomarker Signatures and Candidate Drugs in Colorectal Cancer: Insights from Systems Biology Analysis., PMID:30658502
Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment., PMID:30407575
3D genomic architecture reveals that neocentromeres associate with heterochromatin regions., PMID:30396998
CENP-C/H/I/K/M/T/W/N/L and hMis12 but not CENP-S/X participate in complex formation in the nucleoplasm of living human interphase cells outside centromeres., PMID:29509805
CENPH Inhibits Rapamycin Sensitivity by Regulating GOLPH3-dependent mTOR Signaling Pathway in Colorectal Cancer., PMID:28819418
CENP-H regulates the cell growth of human hepatocellular carcinoma cells through the mitochondrial apoptotic pathway., PMID:28498417
CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes., PMID:27993978
Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis., PMID:26378239
Dynamic changes in CCAN organization through CENP-C during cell-cycle progression., PMID:26354420
Upregulation of centromere protein H is associated with progression of renal cell carcinoma., PMID:26248586
Down-regulation of Sp1 suppresses cell proliferation, clonogenicity and the expressions of stem cell markers in nasopharyngeal carcinoma., PMID:25099028
The pseudo GTPase CENP-M drives human kinetochore assembly., PMID:25006165
Overexpression of CENP-H as a novel prognostic biomarker for human hepatocellular carcinoma progression and patient survival., PMID:23970101
Clinical Significance of CENP-H Expression in Uterine Cervical Cancer., PMID:23691478
Low prevalence of autoantibodies to CENP-H, -I, -K, -L, -M, -N, -T and -U in a Japanese cohort of anti-centromere positive samples., PMID:23083211
Combined evaluation of centromere protein H and Ki-67 as prognostic biomarker for patients with gastric carcinoma., PMID:22999412
Sp1 and Sp3 are involved in the full transcriptional activity of centromere protein H in human nasopharyngeal carcinoma cells., PMID:22682030
Role of centromere protein H and Ki67 in relapse-free survival of patients after primary surgery for hypopharyngeal cancer., PMID:22631655
A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint., PMID:22426531
[Role of centromere protein H in human gastric cancer cell proliferation]., PMID:22381774
Anti-CENPI autoantibodies in scleroderma patients with features of autoimmune liver diseases., PMID:21888900
Overexpression of centromere protein H is significantly associated with breast cancer progression and overall patient survival., PMID:21880184
Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation., PMID:21875947
The Aspergillus nidulans CENP-E kinesin motor KipA interacts with the fungal homologue of the centromere-associated protein CENP-H at the kinetochore., PMID:21392133
Novel somatic frameshift mutations of genes related to cell cycle and DNA damage response in gastric and colorectal cancers with microsatellite instability., PMID:21388066
The fate of metaphase kinetochores is weighed in the balance of SUMOylation during S phase., PMID:20724819
Interruption of cenph causes mitotic failure and embryonic death, and its haploinsufficiency suppresses cancer in zebrafish., PMID:20573960
Dual recognition of CENP-A nucleosomes is required for centromere assembly., PMID:20566683
Vertebrate kinetochore protein architecture: protein copy number., PMID:20548100
A super-resolution map of the vertebrate kinetochore., PMID:20483991
Molecular control of kinetochore-microtubule dynamics and chromosome oscillations., PMID:20228811
Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier., PMID:19656847
CENP-H-containing complex facilitates centromere deposition of CENP-A in cooperation with FACT and CHD1., PMID:19625449
Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N., PMID:19543270
Upregulation of CENP-H in tongue cancer correlates with poor prognosis and progression., PMID:19500341
CENP-K and CENP-H may form coiled-coils in the kinetochores., PMID:19381461
TRIM36 interacts with the kinetochore protein CENP-H and delays cell cycle progression., PMID:19232519
Centromere protein H is a novel prognostic marker for human nonsmall cell lung cancer progression and overall patient survival., PMID:19170237
For research use only. Not for human or drug use.
