Catalog No.
YHJ54001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met106-Trp539
Predicted molecular weight
74.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H0H5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CYK4, Male germ cell RacGap, RACGAP1, Rac GTPase-activating protein 1, HsCYK-4, KIAA1478, MGCRACGAP, MgcRacGAP, Protein CYK4 homolog
RACGAP1 promotes tumor progression by influencing neutrophil recruitment and tumor cell proliferation in colorectal cancer., PMID:40504027
RacGAP1 Plays an Oncogenic Role in Lung Adenocarcinoma by Regulating the Wnt/β-Catenin Pathway., PMID:40497948
GWAS identifies genetic loci for antibody response to SARS-CoV-2 vaccines in patients with systemic autoimmune diseases and healthy individuals., PMID:40463545
Centralspindlin is partially required for C. elegans anchor cell specification, vulval induction and morphogenesis., PMID:40379077
Identification of key biomarkers in breast cancer based on bioinformatics analysis and experimental verification., PMID:39988630
Kinesin-like protein KIF18A is required for faithful coordination of chromosome congression with cytokinesis., PMID:39954259
Statistical and machine learning based platform-independent key genes identification for hepatocellular carcinoma., PMID:39908244
MARCH5 ameliorates aortic valve calcification via RACGAP1-DRP1 associated mitochondrial quality control., PMID:39880131
Biomarker Panels Associated with Diagnosis and Overall Survival in Hepatocellular Carcinoma Revealed from Protein-Protein and mRNA-miRNA Interaction Networks., PMID:39874008
The Expression Regulation and Cancer-Promoting Roles of RACGAP1., PMID:39858398
An Integrated Framework to Identify Prognostic Biomarkers and Novel Therapeutic Targets in Hepatocellular Carcinoma-Based Disabilities., PMID:39765633
Targeting RACGAP1 suppresses growth hormone pituitary adenoma growth., PMID:39607642
Integrating bioinformatics and machine learning methods to analyze diagnostic biomarkers for HBV-induced hepatocellular carcinoma., PMID:39095799
RACGAP1 is a pivotal gene in lung adenocarcinoma-associated membranous nephropathy: Based on comprehensive bioinformatics analysis and machine learning., PMID:39068752
Discovery of differentially expressed proteins for CAR-T therapy of ovarian cancers with a bioinformatics analysis., PMID:39033780
Reciprocal regulation between RACGAP1 and AR contributes to endocrine therapy resistance in prostate cancer., PMID:38898473
RACGAP1 knockdown synergizes and enhances the effects of chemotherapeutics on ovarian cancer., PMID:38883382
Unravelling the molecular mechanistic pathway underlying the anticancer effects of kaempferol in colorectal cancer: a reverse pharmacology network approach., PMID:38795259
Binucleated human hepatocytes arise through late cytokinetic regression during endomitosis M phase., PMID:38727809
Identification of MAD2L1 and BUB1B as Potential Biomarkers Associated with Progression and Prognosis of Ovarian Cancer., PMID:38683465
RACGAP1 promotes lung cancer cell proliferation through the PI3K/AKT signaling pathway., PMID:38622149
Differential DNA methylation associated with delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: a systematic review., PMID:38594575
Constructing lactylation-related genes prognostic model to effectively predict the disease-free survival and treatment responsiveness in prostate cancer based on machine learning., PMID:38566813
RACGAP1 drives proliferation, migration and invasion and suppresses autophagy of gastric cancer cells via inhibiting SIRT1/Mfn2., PMID:38261006
Simulated microgravity altered the gene expression profiles and inhibited the proliferation of Kupffer cells in the early phase by downregulating LMO2 and EZH2., PMID:38245345
FOXM1 transcriptional regulation of RacGAP1 activates the PI3K/AKT signaling pathway to promote the proliferation, migration, and invasion of cervical cancer cells., PMID:38172354
The integrative multi-omics approach identifies the novel competing endogenous RNA (ceRNA) network in colorectal cancer., PMID:37945594
RRP9 and DDX21 as new biomarkers of colorectal cancer., PMID:37904456
Role of TOP2A and CDC6 in liver cancer., PMID:37861550
A Network of 17 Microtubule-Related Genes Highlights Functional Deregulations in Breast Cancer., PMID:37835564
HIF‑1α and RACGAP1 promote the progression of hepatocellular carcinoma in a mutually regulatory way., PMID:37772389
Racgap1 knockdown results in cells with multiple cilia due to cytokinesis failure., PMID:37771269
m6A-modified circASXL1 promotes proliferation and migration of ovarian cancer through the miR-320d/RACGAP1 axis., PMID:37738681
Oncogenic and immunological roles of RACGAP1 in pan-cancer and its potential value in nasopharyngeal carcinoma., PMID:37670104
Invasive Breast Cancer: miR-24-2 Targets Genes Associated with Survival and Sensitizes MDA-MB-231 Cells to Berberine., PMID:37669117
AhR may be involved in Th17 cell differentiation in chronic hepatitis B., PMID:37608767
Rac GTPase activating protein 1 promotes the glioma growth by regulating the expression of MCM3., PMID:37595394
KNTC1 and MCM2 are the molecular targets of gallbladder cancer., PMID:37480569
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling., PMID:37454211
Prognostic model based on telomere-related genes predicts the risk of oral squamous cell carcinoma., PMID:37452322
Telomere-related prognostic biomarkers for survival assessments in pancreatic cancer., PMID:37391503
Galanin 2 Receptor: A Novel Target for a Subset of Pancreatic Ductal Adenocarcinoma., PMID:37373336
SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice., PMID:37039821
Identification of Drug Targets and Agents Associated with Hepatocellular Carcinoma through Integrated Bioinformatics Analysis., PMID:36786134
Exploring the causality and pathogenesis of systemic lupus erythematosus in breast cancer based on Mendelian randomization and transcriptome data analyses., PMID:36726984
Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement., PMID:36630496
Significance of Identifying Key Genes Involved in HBV-Related Hepatocellular Carcinoma for Primary Care Surveillance of Patients with Cirrhosis., PMID:36553600
Assessment of RACGAP1 as a Prognostic and Immunological Biomarker in Multiple Human Tumors: A Multiomics Analysis., PMID:36430577
Unravelling hub genes as potential therapeutic targets in lung cancer using integrated transcriptomic meta-analysis and in silico approach., PMID:36318595
Transcription profiling of feline mammary carcinomas and derived cell lines reveals biomarkers and drug targets associated with metabolic and cell cycle pathways., PMID:36220861
For research use only. Not for human or drug use.
