Catalog No.
YHJ53101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn706-Lys886
Predicted molecular weight
22.70 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9C0A0
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Contactin-associated protein-like 4, KIAA1763, Cell recognition molecule Caspr4, CNTNAP4, CASPR4
Note
For research use only.
Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains., PMID:12093160
Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients., PMID:18398821
Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia., PMID:22661486
Effects of chronic stress on prefrontal cortex transcriptome in mice displaying different genetic backgrounds., PMID:22836882
A common copy number variation (CNV) polymorphism in the CNTNAP4 gene: association with aging in females., PMID:24223195
Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission., PMID:24870235
A common copy number variation polymorphism in the CNTNAP2 gene: sexual dimorphism in association with healthy aging and disease., PMID:25139204
Caspr4 interaction with LNX2 modulates the proliferation and neuronal differentiation of mouse neural progenitor cells., PMID:25279559
High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism., PMID:26307085
Distortion of the normal function of synaptic cell adhesion molecules by genetic variants as a risk for autism spectrum disorders., PMID:27743928
Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures., PMID:28055971
CNTNAP4 Impacts Epilepsy Through GABAA Receptors Regulation: Evidence From Temporal Lobe Epilepsy Patients and Mouse Models., PMID:28968899
Structure and function of the contactin-associated protein family in myelinated axons and their relationship with nerve diseases., PMID:29090003
RNA sequencing and differential expression reveals the effects of serial oestrus synchronisation on ovarian genes in dairy goats., PMID:29875030
Neurexin Superfamily Cell Membrane Receptor Contactin-Associated Protein Like-4 (Cntnap4) Is Involved in Neural EGFL-Like 1 (Nell-1)-Responsive Osteogenesis., PMID:29905970
Nell-1 Is a Key Functional Modulator in Osteochondrogenesis and Beyond., PMID:31610747
The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells., PMID:32107390
CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes., PMID:32194851
Proteomic analysis reveals a biosignature of decreased synaptic protein in cerebrospinal fluid of major depressive disorder., PMID:32398672
Clinical significance of long non-coding RNA DUXAP8 and its protein coding genes in hepatocellular carcinoma., PMID:32922554
Copy number variations in a Brazilian cohort with autism spectrum disorders highlight the contribution of cell adhesion genes., PMID:34664255
Lactobacillus reuteri normalizes altered fear memory in male Cntnap4 knockout mice., PMID:36395738
CNTNAP4 signaling regulates osteosarcoma disease progression., PMID:36599925
Cntnap4 partial deficiency exacerbates α-synuclein pathology through astrocyte-microglia C3-C3aR pathway., PMID:37087484
Microglial targeted therapy relieves cognitive impairment caused by Cntnap4 deficiency., PMID:37933376
Early B Cell Factor 3 (EBF3) attenuates Parkinson's disease through directly regulating contactin-associated protein-like 4 (CNTNAP4) transcription: An experimental study., PMID:38479556
Novel insights into Cntnap4 in Alzheimer's disease: Intestinal flora interaction., PMID:39647729
Histone H3 lysine 9 tri-methylation is associated with pterygium., PMID:40033254
Investigation of the transcriptome and metabolome of the cerebral cortex and testes in Cntnap4-deficient mice., PMID:40262286
For research use only. Not for human or drug use.
