Catalog No.
YHJ52801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro2-Phe360
Predicted molecular weight
42.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BZZ5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
API5, Fibroblast growth factor 2-interacting factor, AAC-11, Apoptosis inhibitor 5, Antiapoptosis clone 11 protein, Protein XAGL, API-5, Cell migration-inducing gene 8 protein, FIF
Salivary proteomics profiling reveals potential biomarkers for chronic kidney disease: a pilot study., PMID:39895822
Identification of the new allele ptc1-2 and analysis of the regulatory role of PTC1 gene in rice anther development., PMID:39528949
Combining multiomics to analyze the molecular mechanism of hair follicle cycle change in cashmere goats from Inner Mongolia., PMID:39036798
Apoptosis Inhibitor 5: A Multifaceted Regulator of Cell Fate., PMID:38275765
API5-Hsp20 axis regulate apoptosis and viral infection in mud crab (Scylla paramamosain)., PMID:38143869
Altered expression of anti-apoptotic protein Api5 affects breast tumorigenesis., PMID:37095445
Identification of the γδ IEL-secreted Paneth Cell Protective Factor API5 as a Promising Therapeutic Target for ATG16L1-associated Crohn's Disease., PMID:36681159
The γδ IEL effector API5 masks genetic susceptibility to Paneth cell death., PMID:36198790
Circ_0060055 Promotes the Growth, Invasion, and Radioresistance of Glioblastoma by Targeting MiR-197-3p/API5 Axis., PMID:35849320
Aspartic protease inhibitor enhances resistance to potato virus Y and A in transgenic potato plants., PMID:35549883
Landfill soil leachates from Nigeria and India induced DNA damage and alterations in genes associated with apoptosis in Jurkat cell., PMID:34417692
Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation., PMID:34385547
DeSUMOylation of Apoptosis Inhibitor 5 by Avibirnavirus VP3 Supports Virus Replication., PMID:34372697
MicroRNA-224 modulates chemosensitivity of breast cancer cells to docetaxel by apoptosis inhibitor 5., PMID:34076992
Potential roles for microRNAs in facilitating physiological adaptation to low-temperature stress in Penaeus vannamei., PMID:34061996
PAK1-Dependent Antitumor Effect of AAC-11‒Derived Peptides on Sézary Syndrome Malignant CD4+ T Lymphocytes., PMID:33745910
Evolution and Structure of API5 and Its Roles in Anti-Apoptosis., PMID:33319655
Inorganic arsenic influences cell apoptosis by regulating the expression of MEG3 gene., PMID:33033900
Regulation of mRNA export through API5 and nuclear FGF2 interaction., PMID:32383752
Antiapoptotic Clone 11-Derived Peptides Induce In Vitro Death of CD4+ T Cells Susceptible to HIV-1 Infection., PMID:32350074
High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target., PMID:31762939
Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5-diamino-6-chloro-N-(N-(2,6-dichlorobenzoyl)carbamimidoyl)pyrazine-2-carboxide., PMID:31152681
PHD finger protein 5A promoted lung adenocarcinoma progression via alternative splicing., PMID:30932358
Long Noncoding RNA-CERNA1 Stabilized Atherosclerotic Plaques in apolipoprotein E-/- Mice., PMID:30888631
Entamoeba histolytica Up-Regulates MicroRNA-643 to Promote Apoptosis by Targeting XIAP in Human Epithelial Colon Cells., PMID:30671387
A novel function of API5 (apoptosis inhibitor 5), TLR4-dependent activation of antigen presenting cells., PMID:30288341
[Expression profile of long non-coding RNA in gingival tissues from the patients with aggressive periodontitis]., PMID:30196627
The anticancer peptide RT53 induces immunogenic cell death., PMID:30080874
Apoptosis inhibitor 5: Role in the inhibition of caspase-2., PMID:29251251
API5 induces cisplatin resistance through FGFR signaling in human cancer cells., PMID:28883546
Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica., PMID:28710039
Endothelial Nitric Oxide Synthase-Independent Pleiotropic Effects of Pitavastatin Against Atherogenesis and Limb Ischemia in Mice., PMID:28592707
Apoptosis inhibitor 5 is an endogenous inhibitor of caspase-2., PMID:28336776
A Cell-Penetrating Peptide Targeting AAC-11 Specifically Induces Cancer Cells Death., PMID:27406828
Long Noncoding RNA LOC100129973 Suppresses Apoptosis by Targeting miR-4707-5p and miR-4767 in Vascular Endothelial Cells., PMID:26887505
A label-free differential proteomics analysis reveals the effect of melatonin on promoting fruit ripening and anthocyanin accumulation upon postharvest in tomato., PMID:26820691
Differential Gene Expression Patterns in Chicken Cardiomyocytes during Hydrogen Peroxide-Induced Apoptosis., PMID:26808997
Nucleoprotein of influenza A virus negatively impacts antiapoptotic protein API5 to enhance E2F1-dependent apoptosis and virus replication., PMID:26673663
Common variants in or near ZNRF1, COLEC12, SCYL1BP1 and API5 are associated with diabetic retinopathy in Chinese patients with type 2 diabetes., PMID:25819896
Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes., PMID:25526772
Tumor suppressors miR-143 and miR-145 and predicted target proteins API5, ERK5, K-RAS, and IRS-1 are differentially expressed in proximal and distal colon., PMID:25477374
MicroRNA-1 promotes apoptosis of hepatocarcinoma cells by targeting apoptosis inhibitor-5 (API-5)., PMID:25433291
Apoptosis Inhibitor 5 Increases Metastasis via Erk-mediated MMP expression., PMID:25248562
Identification of novel candidate biomarkers of epithelial ovarian cancer by profiling the secretomes of three-dimensional genetic models of ovarian carcinogenesis., PMID:25204737
Apoptosis inhibitor-5 overexpression is associated with tumor progression and poor prognosis in patients with cervical cancer., PMID:25070070
Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance., PMID:25004126
Prefrontal cortical and striatal transcriptional responses to the reinforcing effect of repeated methylphenidate treatment in the spontaneously hypertensive rat, animal model of attention-deficit/hyperactivity disorder (ADHD)., PMID:24884696
MiR-224 expression increases radiation sensitivity of glioblastoma cells., PMID:24785373
API5 confers tumoral immune escape through FGF2-dependent cell survival pathway., PMID:24769442
Tumor suppressor function of miR-483-3p on squamous cell carcinomas due to its pro-apoptotic properties., PMID:24067364
For research use only. Not for human or drug use.
