Catalog No.
YHJ51401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His182-Tyr388
Predicted molecular weight
50.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BY76
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PGAR, Angiopoietin-related protein 4, Hepatic fibrinogen/angiopoietin-related protein, ANGPTL4, Angiopoietin-like protein 4, HFARP, ARP4
Proteogenomic and observational evidence implicate ANGPTL4 as a potential therapeutic target for colorectal cancer prevention., PMID:40511612
MicroRNA-6084 orchestrates angiogenesis and liver metastasis in colorectal cancer via extracellular vesicles., PMID:40493409
Transcriptomics characteristics and differentiation of subcutaneous adipose tissue among Huainan pigs and its hybrid genetic populations., PMID:40475027
Growth differentiation factor-8 promotes human extravillous trophoblast cell invasion by increasing ANGPTL4 expression., PMID:40435667
Multi-organ transcriptomics provide insights into growth regulation in the Dongtingking crucian carp (Carassius auratus indigentiaus)., PMID:40398212
Salidroside inhibits osteoclast differentiation based on osteoblast-osteoclast interaction via HIF-1a pathway., PMID:40383613
Safety and efficacy of a novel ANGPTL4 inhibitory antibody for lipid lowering: results from phase 1 and phase 1b/2a clinical studies., PMID:40383129
Atf3 + senescent chondrocytes mediate meniscus degeneration in aging., PMID:40375324
An ANGPTL4 inhibitory antibody safely improves lipid profiles in non-human primates., PMID:40360349
Angiopoietin-like protein inhibitors: Promising agents for the treatment of familial hypercholesterolemia and atherogenic dyslipidemia., PMID:40344904
Transcriptome-wide analysis reveals potential roles of CFD and ANGPTL4 in fibroblasts regulating B cell lineage for extracellular matrix-driven clustering and novel avenues for immunotherapy in breast cancer., PMID:40340806
Unveiling the protective role of ESM1 in endothelial cell proliferation and lipid reprogramming., PMID:40320451
Mixed lineage kinase (MLK) controls tumor development and angiogenesis., PMID:40314847
Angiopoietin-Like Protein Family-Mediated Functions in Modulating Triglyceride Metabolism and Related Metabolic Diseases., PMID:40302331
Metabolism-related hepatokines change in biliary atresia: ANGPTL6 as a potential biomarker., PMID:40281461
ANGPTL4 suppresses progression and improves cisplatin sensitivity in cervical cancer., PMID:40269076
Umbilical Cord Mesenchymal Stem Cells Attenuate Podocyte Injury in Diabetic Nephropathy Rats by Inhibiting Angpltl4/Integrin β3 in the Glomerulus., PMID:40256245
Aqueous humor adipokine profile of primary open angle glaucoma patients and cataract patients with or without metabolic disorders., PMID:40256018
COL1A1-positive endothelial cells promote gastric cancer progression via the ANGPTL4-SDC4 axis driven by endothelial-to-mesenchymal transition., PMID:40254092
The role of ANGPTL4 in cancer: A meta-analysis of observational studies and multi-omics investigation., PMID:40233044
Development of a reliable risk prognostic model for lung adenocarcinoma based on the genes related to endotheliocyte senescence., PMID:40221448
Fish Swim Bladder-Derived ECM Hydrogels Effectively Treat Myocardial Ischemic Injury through Immunomodulation and Angiogenesis., PMID:40200862
miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4., PMID:40191921
Plasma angiopoietin-like protein 4 as a novel biomarker predicting 10-year mortality in a community-based population: a longitudinal cohort study., PMID:40190305
The integrated analysis of transcriptomics and metabolomics reveals the effects of tea polyphenols on lipid metabolism in lion-head geese., PMID:40188624
NDRG1 alleviates Erastin-induced ferroptosis of hepatocellular carcinoma., PMID:40119318
ANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase., PMID:40112106
Serum angiopoietin-like protein 4 levels correlate with hypertriglyceridemia and renal function decline in pediatric patients with lupus nephritis., PMID:40102075
Absence of the intracellular lipolytic inhibitor G0S2 enhances intravascular triglyceride clearance and abolishes diet-induced hypertriglyceridemia., PMID:40100923
Evaluating the Cardiometabolic Efficacy and Safety of Lipoprotein Lipase Pathway Targets in Combination With Approved Lipid-Lowering Targets: A Drug Target Mendelian Randomization Study., PMID:40052268
Exploring Potential Drug Targets in Multiple Cardiovascular Diseases: A Study Based on Proteome-Wide Mendelian Randomization and Colocalization Analysis., PMID:40026415
Protein Drug Targets for Abdominal Aortic Aneurysm and Proteomic Associations Between Modifiable Risk Factors and Abdominal Aortic Aneurysm., PMID:40008516
Elevated Plasma Angiopoietin-like 4 Protein Levels in Adult Patients with Dengue., PMID:40006981
The Anti-obesity Effects of Lotus (Nelumbo nucifera Gaertn.) Seed Red Skin (Testa) Catechins by Regulating Lipoprotein Lipase Expression and Activity., PMID:39985678
Serum Angiopoietin-Like Protein 4 as a Biomarker for Acute Ischemic Stroke Severity and Dynamic Changes., PMID:39972951
High-Glucose-Induced Metabolic and Redox Alterations Are Distinctly Modulated by Various Antidiabetic Agents and Interventions Against FABP5/7, MITF and ANGPTL4 in Melanoma A375 Cells., PMID:39940783
Identifying novel drug targets for calcific aortic valve disease through Mendelian randomization., PMID:39922081
Oncometabolite D-2HG drives tumor metastasis and protumoral macrophage polarization by targeting FTO/m6A/ANGPTL4/integrin axis in triple-negative breast cancer., PMID:39910592
Multilayer regulation of postprandial triglyceride metabolism in response to acute cold exposure., PMID:39892721
MiR-5586-5p Suppresses Hypoxia-induced Angiogenesis Through Multiple Targeting of HIF-1α, HBEGF and ADAM17 in Breast Cancer., PMID:39890164
Transcriptome Analysis Suggests PKD3 Regulates Proliferative Glucose Metabolism, Calcium Homeostasis and Microtubule Dynamics After MEF Spontaneous Immortalization., PMID:39859313
Angiopoietin-like protein 4 dysregulation in kidney diseases: a promising biomarker and therapeutic target., PMID:39840089
Predictive Value of Lung Ultrasound Scores Combined with Serum ANGPTL4 Levels on Severity and Prognosis of Neonatal Respiratory Distress Syndrome., PMID:39830140
Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1., PMID:39814316
Advancing the clinical assessment of glomerular podocyte pathology in kidney biopsies via super-resolution microscopy and angiopoietin-like 4 staining., PMID:39776814
ANGPTL4 induces Kupffer cell M2 polarization to mitigate acute rejection in liver transplantation., PMID:39762255
Clostridium difficile-derived membrane vesicles promote fetal growth restriction via inhibiting trophoblast motility through PPARγ/RXRα/ANGPTL4 axis., PMID:39741137
Identification and Evaluation of Angiogenesis-Related Proteins That Predict Major Adverse Cardiovascular Events in Patients with Peripheral Artery Disease., PMID:39728292
FGF19-Activated Hepatic Stellate Cells Release ANGPTL4 that Promotes Colorectal Cancer Liver Metastasis., PMID:39716892
ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target., PMID:39707362
For research use only. Not for human or drug use.
