Catalog No.
YHJ50301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Glu397
Predicted molecular weight
43.66 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BWD1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ACAT2, ACTL, Acetyl-CoA transferase-like protein, Acetyl-CoA acetyltransferase, cytosolic, Cytosolic acetoacetyl-CoA thiolase
GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRASG12D-mutant cancer., PMID:40503938
Multi-omics unveils BCAA metabolism markers L-leucine and HMGCS1 as prognostic marker for immunotherapy efficacy in non-small cell lung cancer., PMID:40457349
Identification of ARV1 Gene Mutations in Three Pediatric Cases of Developmental and Epileptic Encephalopathy., PMID:40416165
Identification and Validation of Ferritinophagy-Related Biomarkers in Periodontitis., PMID:40233623
ACAT1/SOAT1 maintains adipogenic ability in preadipocytes by regulating cholesterol homeostasis., PMID:39481851
Talabostat, fibroblast activation protein inhibitor, attenuates inflammation and fibrosis in systemic sclerosis., PMID:39167314
Core biomarkers analysis benefit for diagnosis on human intrahepatic cholestasis of pregnancy., PMID:39127651
ACAT2 negatively modulated by FOXA2 suppresses ferroptosis to expedite the aggressive phenotypes of endometrial cancer cells., PMID:39077810
Anti-atherosclerotic effect of tetrahydroxy stilbene glucoside via dual-targeting of hepatic lipid metabolisms and aortic M2 macrophage polarization in ApoE-/- mice., PMID:38971092
β-sitosterol alleviates high fatty acid-induced lipid accumulation in calf hepatocytes by regulating cholesterol metabolism., PMID:38740074
Proteomics Reveals the Obstruction of Cellular ATP Synthesis in the Ruminal Epithelium of Growth-Retarded Yaks., PMID:38672391
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7., PMID:38670954
Bioinformatics and system biology approaches to determine the connection of SARS-CoV-2 infection and intrahepatic cholangiocarcinoma., PMID:38648205
New evidence for gut-muscle axis: Lactic acid bacteria-induced gut microbiota regulates duck meat flavor., PMID:38636385
Microbe-derived Antioxidants Enhance Lipid Synthesis by Regulating the Hepatic AMPKα-SREBP1c Pathway in Weanling Piglets., PMID:38340959
ACAT2 may be a novel predictive biomarker and therapeutic target in lung adenocarcinoma., PMID:38213102
Evaluation of probiotic bifidobacteria strains from Iranian traditional dairy products for their anti-hyperlipidemic potential., PMID:38198044
High-expressed ACAT2 predicted the poor prognosis of platinum-resistant epithelial ovarian cancer., PMID:38178203
The modulatory effects on enterohepatic cholesterol metabolism of novel cholesterol-lowering peptides from gastrointestinal digestion of Xuanwei ham., PMID:37803728
Subclinical ketosis leads to lipid metabolism disorder by downregulating the expression of acetyl-coenzyme A acetyltransferase 2 in dairy cows., PMID:37690731
Identification of Zip8-correlated hub genes in pulmonary hypertension by informatic analysis., PMID:37663293
Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer's Disease Mice., PMID:37446191
Regulation of cholesterol metabolism during high fatty acid-induced lipid deposition in calf hepatocytes., PMID:37419743
Appropriate cold stimulation changes energy distribution to improve stress resistance in broilers., PMID:37279534
Citri Reticulatae Pericarpium-Reynoutria japonica Houtt. herb pair suppresses breast cancer liver metastasis by targeting ECM1-mediated cholesterol biosynthesis pathway., PMID:37247588
Acetyl-CoA Acetyltransferase 2 Confers Radioresistance by Inhibiting Ferroptosis in Esophageal Squamous Cell Carcinoma., PMID:37244629
Luteolin Mitigates Diabetic Dyslipidemia in Rats by Modulating ACAT-2, PPARα, SREBP-2 Proteins, and Oxidative Stress., PMID:37103741
G protein-coupled receptor 35 attenuates nonalcoholic steatohepatitis by reprogramming cholesterol homeostasis in hepatocytes., PMID:36970193
The Effects of a High-Fat/Cholesterol Diet on the Intestine of Rats Were Attenuated by Sparassis latifolia Polysaccharides., PMID:36816874
Multi-omics analysis the differences of VOCs terpenoid synthesis pathway in maintaining obligate mutualism between Ficus hirta Vahl and its pollinators., PMID:36457527
Krill Oil Inhibits Cholesterol Synthesis and Stimulated Cholesterol Excretion in Hypercholesterolemic Rats., PMID:36286433
Could Duodenal Molecular Mechanisms be Involved in the Hypocholesterolemic Effect of Silicon Used as Functional Ingredient in Late-Stage Type 2 Diabetes Mellitus?, PMID:36213967
Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning., PMID:36211422
Dietary astaxanthin-rich extract ameliorates atherosclerosis/retinopathy and restructures gut microbiome in apolipoprotein E-deficient mice fed on a high-fat diet., PMID:36134474
Human tau mutations in cerebral organoids induce a progressive dyshomeostasis of cholesterol., PMID:35985329
Role of sortilin 1 (SORT1) on fatty acid-mediated cholesterol metabolism in primary calf hepatocytes., PMID:35940922
PCSK9 Contributes to the Cholesterol, Glucose, and Insulin2 Homeostasis in Seminiferous Tubules and Maintenance of Immunotolerance in Testis., PMID:35586340
HOXA10 Regulates the Synthesis of Cholesterol in Endometrial Stromal Cells., PMID:35546998
Phenotype-genotype correlation in aldosterone-producing adenomas characterized by intracellular cholesterol metabolism., PMID:35533918
Great Northern Beans (Phaseolus vulgaris L.) Lower Cholesterol in Hamsters Fed a High-Saturated-Fat Diet., PMID:35511604
Complex Involvement of the Extracellular Matrix, Immune Effect, and Lipid Metabolism in the Development of Idiopathic Pulmonary Fibrosis., PMID:35174208
Correlation of cholesteryl ester metabolism to pathogenesis, progression and disparities in colorectal Cancer., PMID:35172832
Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice., PMID:34982494
Acetylation Profiles in the Metabolic Process of Glioma-Associated Seizures., PMID:34664012
Pan-cancer analysis reveals the oncogenic role of 3-hydroxy-3-methylglutaryl-CoA synthase 1., PMID:34549901
Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis., PMID:34151243
A defective interleukin-17 receptor A1 causes weight loss and intestinal metabolism-related gene downregulation in Japanese medaka, Oryzias latipes., PMID:34103614
Effects of Three-Month Administration of High-Saturated Fat Diet and High-Polyunsaturated Fat Diets with Different Linoleic Acid (LA, C18:2n-6) to α-Linolenic Acid (ALA, C18:3n-3) Ratio on the Mouse Liver Proteome., PMID:34063343
Circ_RPL23A acts as a miR-1233 sponge to suppress the progression of clear cell renal cell carcinoma by promoting ACAT2., PMID:34036483
Maternal Vitamin and Mineral Supplementation and Rate of Maternal Weight Gain Affects Placental Expression of Energy Metabolism and Transport-Related Genes., PMID:33803164
For research use only. Not for human or drug use.
