Catalog No.
YHJ50201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg130-Leu368
Predicted molecular weight
29.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BW27
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Pericentrin-1, Nucleoporin Nup85, Nucleoporin Nup75, PCNT1, 85 kDa nucleoporin, NUP75, NUP85, Nuclear pore complex protein Nup85, FROUNT
Loss of Nup160 dysregulates Cdc42 in the podocytes of podocyte-specific Nup160 knockout mice., PMID:40298220
Shared Genomic Features Between Lung Adenocarcinoma and Type 2 Diabetes: A Bioinformatics Study., PMID:40282196
A Novel NUP85 Variant Expanding the Phenotypic Spectrum of NUP85-Associated Steroid-Resistant Nephrotic Syndrome., PMID:39949197
Genetic and clinical spectrum of steroid-resistant nephrotic syndrome with nuclear pore gene mutation., PMID:39814977
Nucleoporin-associated steroid-resistant nephrotic syndrome., PMID:39331077
Docking a flexible basket onto the core of the nuclear pore complex., PMID:39138317
[Analysis of correlation between high expression of nucleoporin 85 (NUP85) and immune cell infiltration in hepatocellular carcinoma]., PMID:38952090
NUP85 alleviates lipid metabolism and inflammation by regulating PI3K/AKT signaling pathway in nonalcoholic fatty liver disease., PMID:38617542
Predicting Functional Consequences of Recent Natural Selection in Britain., PMID:38466119
Mutations in nuclear pore complex promote osmotolerance in Arabidopsis by suppressing the nuclear translocation of ACQOS and its osmotically induced immunity., PMID:38318497
Nuclear pore complex proteins are involved in centromere distribution., PMID:38318384
NUP85 as a Neurodevelopmental Gene: From Podocyte to Neuron., PMID:38136965
Predicting functional consequences of recent natural selection in Britain., PMID:37904954
Deficient chaperone-mediated autophagy in macrophage aggravates inflammation of nonalcoholic steatohepatitis by targeting Nup85., PMID:36912786
Expanded FLP toolbox for spatiotemporal protein degradation and transcriptomic profiling in Caenorhabditis elegans., PMID:36321973
Nucleoporin 85 interacts with influenza A virus PB1 and PB2 to promote its replication by facilitating nuclear import of ribonucleoprotein., PMID:36051755
A novel ferroptosis-related gene prognostic index for prognosis and response to immunotherapy in patients with prostate cancer., PMID:36034466
Shared genetic loci for body fat storage and adipocyte lipolysis in humans., PMID:35256633
Expanding the phenotype of NUP85 mutations beyond nephrotic syndrome to primary autosomal recessive microcephaly and Seckel syndrome spectrum disorders., PMID:34170319
Integrity of the short arm of the nuclear pore Y-complex is required for mouse embryonic stem cell growth and differentiation., PMID:34037234
Rational Design of Monodispersed Mutants of Proteins by Identifying Aggregation Contact Sites Using Solubilizing Agents., PMID:32929969
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis., PMID:32376910
The potential role of chitosan-based nanoparticles as drug delivery systems in pancreatic cancer., PMID:32057169
Nuclear pore complex components have temperature-influenced roles in plant growth and immunity., PMID:32022936
Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties., PMID:32001710
Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome., PMID:30179222
Frontline Science: Buprenorphine decreases CCL2-mediated migration of CD14+ CD16+ monocytes., PMID:29791013
1H, 13C and 15N resonance assignments for a chemokine receptor-binding domain of FROUNT, a cytoplasmic regulator of chemotaxis., PMID:29594928
Efficient identification of compounds suppressing protein precipitation via solvent screening using serial deletion mutants of the target protein., PMID:29292854
An Arabidopsis Nucleoporin NUP85 modulates plant responses to ABA and salt stress., PMID:29232718
Identification and Preparation of a Novel Chemokine Receptor-Binding Domain in the Cytoplasmic Regulator FROUNT., PMID:28342149
Crystal structure of human nuclear pore complex component NUP43., PMID:26391640
Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT., PMID:25283965
Probing nuclear pore complex architecture with proximity-dependent biotinylation., PMID:24927568
Analysis of the Lotus japonicus nuclear pore NUP107-160 subcomplex reveals pronounced structural plasticity and functional redundancy., PMID:24478780
Rhizobial infection does not require cortical expression of upstream common symbiosis genes responsible for the induction of Ca(2+) spiking., PMID:24329948
Identification of a binding element for the cytoplasmic regulator FROUNT in the membrane-proximal C-terminal region of chemokine receptors CCR2 and CCR5., PMID:24128342
Identification of the cell targets important for propolis-induced cell death in Candida albicans., PMID:23856128
Characterization of the ptr5+ gene involved in nuclear mRNA export in fission yeast., PMID:22240020
Expression and purification of human FROUNT, a common cytosolic regulator of CCR2 and CCR5., PMID:21193048
FROUNT is a common regulator of CCR2 and CCR5 signaling to control directional migration., PMID:19841162
Structure of a trimeric nucleoporin complex reveals alternate oligomerization states., PMID:19805193
Nup120: one more piece in the NPC puzzle., PMID:19679081
A lattice model of the nuclear pore complex., PMID:19641729
The structure of the scaffold nucleoporin Nup120 reveals a new and unexpected domain architecture., PMID:19576787
A fence-like coat for the nuclear pore membrane., PMID:19111661
Structural evidence for common ancestry of the nuclear pore complex and vesicle coats., PMID:18974315
CCL2 induces prostate cancer transendothelial cell migration via activation of the small GTPase Rac., PMID:18646053
A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export., PMID:18046452
[FROUNT, a regulator of monocytes/macrophage chemotaxis]., PMID:18027578
For research use only. Not for human or drug use.
