Catalog No.
YHJ49601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys258-Cys455
Predicted molecular weight
24.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BTC0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Death-inducer obliterator 1, DIO-1, DATF1, C20orf158, KIAA0333, hDido1, DIDO1, Death-associated transcription factor 1, DATF-1
Correction: CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1‑529aa protein and regulating PRDX2 protein stability., PMID:40394652
Detection of Microsatellite Instability in Endometrial Carcinoma Using a Novel Homopolymer Assay., PMID:40033864
Use of antibodies against Epstein-Barr virus nuclear antigen 1 for detection of cellular proteins with monomethylated arginine residues that are potentially involved in viral transformation., PMID:39514105
PARP1, DIDO3, and DHX9 Proteins Mutually Interact in Mouse Fibroblasts, with Effects on DNA Replication Dynamics, Senescence, and Oncogenic Transformation., PMID:38247850
DIDO is necessary for the adipogenesis that promotes diet-induced obesity., PMID:38194457
Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity., PMID:37601970
The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators., PMID:36631525
Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing., PMID:35672775
The Dengue Virus Nonstructural Protein 1 (NS1) Interacts with the Putative Epigenetic Regulator DIDO1 to Promote Flavivirus Replication in Mosquito Cells., PMID:35652656
Insights into the Mechanism of Human Deiodinase 1., PMID:35628173
Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis., PMID:35099348
Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing., PMID:34871736
Mechanically transduced immunosorbent assay to measure protein-protein interactions., PMID:34581668
CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability., PMID:34384442
Contributions of methionine to recognition of trimethyllysine in aromatic cage of PHD domains: implications of polarizability, hydrophobicity, and charge on binding., PMID:34257891
Novel DIO1 Gene Mutation Acting as Phenotype Modifier for Novel Compound Heterozygous TPO Gene Mutations Causing Congenital Hypothyroidism., PMID:34128397
Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke., PMID:34103026
Hemoglobin overexpression and splice signature as new features of inflammatory breast cancer?, PMID:33364047
Deiodinases, organic anion transporter polypeptide polymorphisms and symptoms of anxiety and depression after ischemic stroke., PMID:32807452
BAP1 maintains chromosome stability by stabilizing DIDO1 in renal cell carcinoma., PMID:32509391
Death-inducer obliterator 1 (DIDO1) silencing suppresses growth of bladder cancer cells through decreasing SAPK/JNK signaling cascades., PMID:32484699
Deiodinases, organic anion transporter polypeptide polymorphisms and ischemic stroke outcomes., PMID:31677555
SET domain containing 1B gene is mutated in primary hepatic neuroendocrine tumors., PMID:30977120
Dido3-dependent SFPQ recruitment maintains efficiency in mammalian alternative splicing., PMID:30931476
Role of DIDO1 in Progression of Esophageal Squamous Cell Carcinoma., PMID:30761474
Correlation between SALL4 stemness marker and bone morphogenetic protein signaling genes in esophageal squamous cell carcinoma., PMID:30431698
Contribution of KCTD12 to esophageal squamous cell carcinoma., PMID:30157793
The relationship between inflammatory factors, oxidative stress and DIO-1 concentration in patients with chronic renal failure accompanied with or without euthyroid sick syndrome., PMID:30152254
Investigation of the Oxidative Stress and DIO1 Expression in CRF Patients Accompanied With and Without Euthyroid Sick Syndrome., PMID:29894998
Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients., PMID:29321381
Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity., PMID:29228274
A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO., PMID:28919441
Genome-wide association analysis identifies genetic correlates of immune infiltrates in solid tumors., PMID:28749946
DIDO as a Switchboard that Regulates Self-Renewal and Differentiation in Embryonic Stem Cells., PMID:28330622
Identification of TWIST-interacting genes in prostate cancer., PMID:28120266
Polymorphisms of iodothyronine deiodinases (DIO1, DIO3) genes are not associated with recurrent depressive disorder., PMID:27351946
The expression of Death Inducer-Obliterator (DIDO) variants in Myeloproliferative Neoplasms., PMID:27282563
Knock-Down of Endogenous Bornavirus-Like Nucleoprotein 1 Inhibits Cell Growth and Induces Apoptosis in Human Oligodendroglia Cells., PMID:27023521
An Improved Nonradioactive Screening Method Identifies Genistein and Xanthohumol as Potent Inhibitors of Iodothyronine Deiodinases., PMID:25962824
Identification and validation of genetic variants that influence transcription factor and cell signaling protein levels., PMID:25087611
Proteomic characterization of human coronary thrombus in patients with ST-segment elevation acute myocardial infarction., PMID:25065646
The death-inducer obliterator 1 (Dido1) gene regulates embryonic stem cell self-renewal., PMID:24347171
mRNA expression pattern of retinoic acid and retinoid X nuclear receptor subtypes in human thyroid papillary carcinoma., PMID:23969901
New targets for the antitumor activity of gambogic acid in hematologic malignancies., PMID:23274413
CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression., PMID:22711543
Death inducer-obliterator 1 (Dido1) is a BMP target gene and promotes BMP-induced melanoma progression., PMID:22469980
TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression., PMID:22207630
Forkhead box A1 (FOXA1) and A2 (FOXA2) oppositely regulate human type 1 iodothyronine deiodinase gene in liver., PMID:22067325
Toward a comprehensive characterization of the phosphotyrosine proteome., PMID:21447384
Chronic stress and impaired glutamate function elicit a depressive-like phenotype and common changes in gene expression in the mouse frontal cortex., PMID:20937555
For research use only. Not for human or drug use.
