Catalog No.
YHJ48101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu2368-Glu2627
Predicted molecular weight
31.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99973
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
p240, TLP1, Telomerase-associated protein 1, Telomerase protein component 1, p80 telomerase homolog, Telomerase protein 1, TP1, TEP1
Effects of Pharmacological Treatment on Telomere Length and the Expression of Telomerase/Shelterin-Related Genes in Rat Models of Autism., PMID:40272729
Thioester-containing protein TEP15 promotes malaria parasite development in mosquitoes through negative regulation of melanization., PMID:40170182
Targeting the mosquito prefoldin-chaperonin complex blocks Plasmodium transmission., PMID:40050397
Exploring the role of vault complex in the nervous system: a literature review., PMID:39584466
Genotype distribution and allele frequency of thioester-containing protein 1(Tep1) and its effect on development of Plasmodium oocyst in populations of Anopheles arabiensis in Ethiopia., PMID:39383173
Dihydroartemisinin suppresses the susceptibility of Anopheles stephensi to Plasmodium yoelii by activating the Toll signaling pathway., PMID:39363238
Late sporogonic stages of Plasmodium parasites are susceptible to the melanization response in Anopheles gambiae mosquitoes., PMID:39149419
Structure, Dynamics and Functional Implications of the Eukaryotic Vault Complex., PMID:38963499
Human Vault RNAs: Exploring Their Potential Role in Cellular Metabolism., PMID:38612882
Effects of HSV-G47Δ Oncolytic Virus on Telomerase and Telomere Length Alterations in Glioblastoma Multiforme Cancer Stem Cells Under Hypoxia and Normoxia Conditions., PMID:38357955
The Anopheles leucine-rich repeat protein APL1C is a pathogen binding factor recognizing Plasmodium ookinetes and sporozoites., PMID:38354186
Key processes required for the different stages of fungal carnivory by a nematode-trapping fungus., PMID:37988381
Gene polymorphisms associated with sudden decreases in heart rate during extensive peritoneal lavage with distilled water after gastrectomy., PMID:37969699
Multiomics and bioinformatics identify differentially expressed effectors in the brain of Toxoplasma gondii infected masked palm civet., PMID:37818043
Quantitative profiling of genes associated with cancer pathways in brain tumors., PMID:37353350
Distribution of Anopheles gambiae thioester-containing protein 1 alleles along malaria transmission gradients in The Gambia., PMID:36899431
Vectorial capacity and TEP1 genotypes of Anopheles gambiae sensu lato mosquitoes on the Kenyan coast., PMID:36457004
The Role of Mosquito Hemocytes in Viral Infections., PMID:36298644
Relative Leukocyte Telomere Length and Telomerase Complex Regulatory Markers Association with Leber's Hereditary Optic Neuropathy., PMID:36143917
Molecular characterization of thioester-containing proteins in Biomphalaria glabrata and their differential gene expression upon Schistosoma mansoni exposure., PMID:35967434
Molecular characterization and genotype distribution of thioester-containing protein 1 gene in Anopheles gambiae mosquitoes in western Kenya., PMID:35948910
Malaria oocysts require circumsporozoite protein to evade mosquito immunity., PMID:35680915
Genetics and immunity of Anopheles response to the entomopathogenic fungus Metarhizium anisopliae overlap with immunity to Plasmodium., PMID:35428783
C-type lectin 4 regulates broad-spectrum melanization-based refractoriness to malaria parasites., PMID:35025886
MVP Expression Facilitates Tumor Cell Proliferation and Migration Supporting the Metastasis of Colorectal Cancer Cells., PMID:34829999
Increased insulin signaling in the Anopheles stephensi fat body regulates metabolism and enhances the host response to both bacterial challenge and Plasmodium falciparum infection., PMID:34666189
hsa_circ_0005721 triggers proliferation, migration and invasion of osteosarcoma by upregulating the linear transcript TEP1., PMID:34565023
TEP1 is a risk gene for sporadic cerebral palsy., PMID:34543729
Genetic variants in telomerase-associated protein 1 are associated with telomere damage in PAH-exposed workers., PMID:34333383
A Thioester-Containing Protein Controls Dengue Virus Infection in Aedes aegypti Through Modulating Immune Response., PMID:34054842
Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools., PMID:33770142
Transcriptome profiles discriminate between Gram-positive and Gram-negative sepsis in preterm neonates., PMID:33767373
Rapamycin inhibits pathogen transmission in mosquitoes by promoting immune activation., PMID:33626094
The Vault Nanoparticle: A Gigantic Ribonucleoprotein Assembly Involved in Diverse Physiological and Pathological Phenomena and an Ideal Nanovector for Drug Delivery and Therapy., PMID:33572350
The Route of Infection Influences the Contribution of Key Immunity Genes to Antibacterial Defense in Anopheles gambiae., PMID:33207342
The CLIP-domain serine protease CLIPC9 regulates melanization downstream of SPCLIP1, CLIPA8, and CLIPA28 in the malaria vector Anopheles gambiae., PMID:33045027
Bacillus sphaericus exposure reduced vector competence of Anopheles dirus to Plasmodium yoelii by upregulating the Imd signaling pathway., PMID:32891162
In silico analysis of proteins and microRNAs related to human African trypanosomiasis in tsetse fly., PMID:32745971
Hemocyte-specific FREP13 abrogates the exogenous bacterial population in the hemolymph and promotes midgut endosymbionts in Anopheles stephensi., PMID:32623757
hsa_circ_0004018 suppresses the progression of liver fibrosis through regulating the hsa-miR-660-3p/TEP1 axis., PMID:32584784
Insect Hemolymph Immune Complexes., PMID:32189298
Identification of rare variants in novel candidate genes in pulmonary atresia patients by next generation sequencing., PMID:32128068
The mosquito melanization response requires hierarchical activation of non-catalytic clip domain serine protease homologs., PMID:31765430
Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection., PMID:31658986
A new role for vault RNA-TEP1 complexes in mRNA production in trypanosomes., PMID:31653772
Independent effects on cellular and humoral immune responses underlie genotype-by-genotype interactions between Drosophila and parasitoids., PMID:31589659
The vault RNA of Trypanosoma brucei plays a role in the production of trans-spliced mRNA., PMID:31439669
A Gut Symbiotic Bacterium Serratia marcescens Renders Mosquito Resistance to Plasmodium Infection Through Activation of Mosquito Immune Responses., PMID:31379768
Anopheles gambiae TEP1 forms a complex with the coiled-coil domain of LRIM1/APL1C following a conformational change in the thioester domain., PMID:31237887
Stimulation of a protease targeting the LRIM1/APL1C complex reveals specificity in complement-like pathway activation in Anopheles gambiae., PMID:30958840