Catalog No.
YHJ47601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Thr384
Predicted molecular weight
44.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99956
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dual specificity protein phosphatase 9, DUSP9, Mitogen-activated protein kinase phosphatase 4, MKP-4, MAP kinase phosphatase 4, MKP4
DUSP9-mediated inhibition of IRS1/PI3K/AKT pathway contributes to insulin resistance and metabolic dysfunction in gestational diabetes mellitus., PMID:40020430
IGF2BP3 prefers to regulate alternative splicing of genes associated with the progression of gastric cancer in AGS cells., PMID:39998701
Caffeine ameliorates metabolic-associated steatohepatitis by rescuing hepatic Dusp9., PMID:39879738
FGFR antagonists restore defective mandibular bone repair in a mouse model of osteochondrodysplasia., PMID:39837840
Inhibition of miR-194-5p avoids DUSP9 downregulation thus limiting sepsis-induced cardiomyopathy., PMID:39218968
m6A-mediated HDAC9 upregulation promotes particulate matter-induced airway inflammation via epigenetic control of DUSP9-MAPK axis and acts as an inhaled nanotherapeutic target., PMID:39088948
Identifying specific TLS-associated genes as potential biomarkers for predicting prognosis and evaluating the efficacy of immunotherapy in soft tissue sarcoma., PMID:38720884
Corrigendum to: DUSP9 alleviates hepatic ischemia/reperfusion injury by restraining both mitogen-activated protein kinase and IKK in an apoptosis signal-regulating kinase 1-dependent manner., PMID:37990617
The coexistence of aflatoxin M1 and ochratoxin A induced intestinal barrier disruption via the regulation of key differentially expressed microRNAs and long non-coding RNAs in BALB/c mice., PMID:37688864
Methyl Syringate Stimulates Glucose Uptake by Inhibiting Protein Tyrosine Phosphatases Relevant to Insulin Resistance., PMID:37374154
Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population., PMID:36980809
DUSP9 alleviates hepatic ischemia/reperfusion injury by restraining both mitogen-activated protein kinase and IKK in an apoptosis signal-regulating kinase 1-dependent manner., PMID:36789693
Terminalin from African Mango (Irvingia gabonensis) Stimulates Glucose Uptake through Inhibition of Protein Tyrosine Phosphatases., PMID:35204821
miR-132-3p Modulates DUSP9-Dependent p38/JNK Signaling Pathways to Enhance Inflammation in the Amnion Leading to Labor., PMID:35163786
Potential Molecular Mechanisms and Remdesivir Treatment for Acute Respiratory Syndrome Corona Virus 2 Infection/COVID 19 Through RNA Sequencing and Bioinformatics Analysis., PMID:34992355
The Cardiac Glycoside Deslanoside Exerts Anticancer Activity in Prostate Cancer Cells by Modulating Multiple Signaling Pathways., PMID:34830961
DUSP9, a Dual-Specificity Phosphatase with a Key Role in Cell Biology and Human Diseases., PMID:34768967
Dual-Specificity Phosphatase 9 Regulates Cellular Proliferation and Predicts Recurrence After Surgery in Hepatocellular Carcinoma., PMID:34278178
Dual-specificity Phosphatase 9 protects against Cardiac Hypertrophy by targeting ASK1., PMID:34239349
Identification of X-chromosomal genes that drive sex differences in embryonic stem cells through a hierarchical CRISPR screening approach., PMID:33863351
Granulosa cell genes that regulate ovarian follicle development beyond the antral stage: The role of estrogen receptor β., PMID:33676987
HSA_CIRC_0004050 on proliferation and apoptosis of A549 cells through ERK/JNK signaling pathway., PMID:33348975
DUSP9-mediated reduction of pERK1/2 supports cancer stem cell-like traits and promotes triple negative breast cancer., PMID:33163285
Downregulation of DUSP9 Promotes Tumor Progression and Contributes to Poor Prognosis in Human Colorectal Cancer., PMID:33072575
Expression Analysis of Tyrosine Phosphatase Genes at Different Stages of Renal Cell Carcinoma., PMID:32988891
Dual specificity phosphatase 9: A novel binding partner cum substrate of proapoptotic serine protease HtrA2., PMID:32988583
EEF1A2 and ERN2 could potentially discriminate metastatic status of mediastinal lymph node in lung adenocarcinomas harboring EGFR 19Del/L858R mutations., PMID:32881299
Diabetes as a risk factor for Alzheimer's disease in the Middle East and its shared pathological mediators., PMID:32210695
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway., PMID:32103999
Expression of Dual-Specificity Phosphatase 9 in Placenta and Its Relationship with Gestational Diabetes Mellitus., PMID:31772940
Identification of chebulinic acid as a dual targeting inhibitor of protein tyrosine phosphatases relevant to insulin resistance., PMID:31284101
Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability., PMID:31151270
[Association of DUSP9 gene polymorphisms with gestational diabetes mellitus]., PMID:30835362
X-Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels., PMID:30639215
[Elucidation of a New Mechanism of Onset of Insulin Resistance: Effects of Statins and Tumor Necrosis Factor-α on Insulin Signal Transduction]., PMID:30381640
Fermented Barley Extracts with Lactobacillus plantarum dy-1 Rich in Vanillic Acid Modulate Glucose Consumption in Human HepG2 Cells., PMID:30369345
Ginkgolic acid as a dual-targeting inhibitor for protein tyrosine phosphatases relevant to insulin resistance., PMID:30153591
Admixture mapping and fine-mapping of type 2 diabetes susceptibility loci in African American women., PMID:30135545
Dual-Specificity Phosphatase 9 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through ASK1 Suppression., PMID:30063256
LincU Preserves Naïve Pluripotency by Restricting ERK Activity in Embryonic Stem Cells., PMID:30017820
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment., PMID:29880481
Antagonistic Interactions between Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and Retinoic Acid Receptor Signaling in Colorectal Cancer Cells., PMID:28483913
DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells., PMID:28366588
Mitogen-Dependent Regulation of DUSP1 Governs ERK and p38 Signaling During Early 3T3-L1 Adipocyte Differentiation., PMID:26566083
Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-β Production., PMID:26170386
Epigenetic silencing of DUSP9 induces the proliferation of human gastric cancer by activating JNK signaling., PMID:25998184
Meta-eQTL: a tool set for flexible eQTL meta-analysis., PMID:25431350
Development of a DUSP9 methylation screening assay., PMID:24838152
A novel intergenic ETnII-β insertion mutation causes multiple malformations in polypodia mice., PMID:24339789
LIF-dependent primitive neural stem cells derived from mouse ES cells represent a reversible stage of neural commitment., PMID:23973799
For research use only. Not for human or drug use.
