Catalog No.
YHJ46701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr459-Asn722
Predicted molecular weight
31.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99767
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MINT2, Amyloid-beta A4 precursor protein-binding family A member 2, Neuronal Munc18-1-interacting protein 2, APBA2, Adapter protein X11beta, Neuron-specific X11L protein, Mint-2, X11L
Evaluation of cerebrospinal fluid (CSF) and interstitial fluid (ISF) mouse proteomes for the validation and description of Alzheimer's disease biomarkers., PMID:39102902
Changes in Expression of Key Genes in Alzheimer's Disease: A Specific Brain Tissue Change., PMID:38267766
Perinatal exposure to the immune-suppressant di-n-octyltin dichloride affects brain development in rats., PMID:37946400
Special transcriptome landscape and molecular prognostic signature of non-smoking head and neck cancer patients., PMID:36882550
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2., PMID:36749163
Identification of epigenetic modifications mediating the antagonistic effect of selenium against cadmium-induced breast carcinogenesis., PMID:34773240
Common genetic signatures of Alzheimer's disease in Down Syndrome., PMID:33633844
Molecular Details of a Coupled Binding and Folding Reaction between the Amyloid Precursor Protein and a Folded Domain., PMID:34161732
Progressive alteration of DNA methylation of Alu, MGMT, MINT2, and TFPI2 genes in colonic mucosa during colorectal cancer development., PMID:34092617
Targeting the APP-Mint2 Protein-Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation., PMID:33398998
A Comprehensive Analysis of Unique and Recurrent Copy Number Variations in Alzheimer's Disease and its Related Disorders., PMID:33256577
Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of alcadein α-deficient mice., PMID:32467230
An integrated analysis of rare CNV and exome variation in Autism Spectrum Disorder using the Infinium PsychArray., PMID:32081867
Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype., PMID:31182603
A rare autism-associated MINT2/APBA2 mutation disrupts neurexin trafficking and synaptic function., PMID:30988517
HCN ion channels and accessory proteins in epilepsy: genetic analysis of a large cohort of patients and review of the literature., PMID:30986657
X11 and X11-like proteins regulate the level of extrasynaptic glutamate receptors., PMID:30411795
Altered social behavior in mice carrying a cortical Foxp2 deletion., PMID:30357341
Thyroid hormone influences brain gene expression programs and behaviors in later generations by altering germ line epigenetic information., PMID:30356120
Nuclear factor I X is a recurrent target for HPV16 insertions in anal carcinomas., PMID:30264502
Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia., PMID:28501592
Change in INSR, APBA2 and IDE Gene Expressions in Brains of Alzheimer's Disease Patients., PMID:28164769
Analysis of peripheral amyloid precursor protein in Angelman Syndrome., PMID:27327493
Expression and localization of X11 family proteins in neurons., PMID:27268412
Serotonin 6 receptor controls Alzheimer's disease and depression., PMID:26449188
Cytoplasmic fragment of Alcadein α generated by regulated intramembrane proteolysis enhances amyloid β-protein precursor (APP) transport into the late secretory pathway and facilitates APP cleavage., PMID:25406318
Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation., PMID:24742670
Circulating methylated MINT2 promoter DNA is a potential poor prognostic factor in gastric cancer., PMID:24385013
Association of AMD-like retinopathy development with an Alzheimer's disease metabolic pathway in OXYS rats., PMID:23959258
Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease., PMID:23883936
Gene expression changes in peripheral blood from Chinese Han patients with Tourette syndrome., PMID:23076970
Intracellular amyloid precursor protein sorting and amyloid-β secretion are regulated by Src-mediated phosphorylation of Mint2., PMID:22787047
Open-closed motion of Mint2 regulates APP metabolism., PMID:22730553
Promoter characterization and genomic organization of the human X11β gene APBA2., PMID:22222501
Molecular features of colorectal hyperplastic polyps and sessile serrated adenoma/polyps from Korea., PMID:21836485
[The neuronal cytoplasmic adaptor protein X11L is involved in APP metabolism]., PMID:21417016
Expression and ultrastructural localization of Mint2 in the spinal cord of rats., PMID:20369384
Expression of the NR2B-NMDA receptor trafficking complex in prefrontal cortex from a group of elderly patients with schizophrenia., PMID:20347576
Copy number and sequence variants implicate APBA2 as an autism candidate gene., PMID:20029827
Novel mediators of amyloid precursor protein signaling., PMID:20016085
Increased epithelial stem cell traits in advanced endometrial endometrioid carcinoma., PMID:20015385
Identification of sexually dimorphic gene expression in brain tissue of the fish Leporinus macrocephalus through mRNA differential display and real time PCR analyses., PMID:19890727
X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice., PMID:19744962
The cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement., PMID:19720620
Microsatellite instability and survival in rectal cancer., PMID:19669908
X11-like protein deficiency is associated with impaired conflict resolution in mice., PMID:19420255
Somatic alterations, metabolizing genes and smoking in rectal cancer., PMID:19358278
Interaction of Mint2 with TrkA is involved in regulation of nerve growth factor-induced neurite outgrowth., PMID:19265194
Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP., PMID:19222704
X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain., PMID:18845544
For research use only. Not for human or drug use.
