Catalog No.
YHJ46201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser77-Ser323
Predicted molecular weight
30.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99719
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PNUTL1, CDCrel-1, Septin-5, Peanut-like protein 1, Cell division control-related protein 1, SEPT5, SEPTIN5
From checkboxes to emojis: a novel approach to patient-reported outcomes in multiple sclerosis., PMID:40447786
Assessing fall risk in multiple sclerosis using patient-reported outcomes and wearable gait metrics., PMID:40292035
Septin5 deletion enhances β-cell exocytosis by releasing microtubule-tethered insulin granules onto plasma membrane., PMID:40108136
Autoimmune encephalitis: recovery, residual symptoms and predictors of long-term sequelae., PMID:39832911
Innovation and optimization in autoimmune encephalitis trials: the design and rationale for the Phase 3, randomized study of satralizumab in patients with NMDAR-IgG-antibody-positive or LGI1-IgG-antibody-positive autoimmune encephalitis (CIELO)., PMID:39193150
Autoimmune Neurobeachin Cerebellar Ataxia., PMID:39165102
Autoimmune Movement Disorders., PMID:39088289
Clinical features and outcomes in primary nervous system histiocytic neoplasms., PMID:38902249
Case Presentation of Autoimmune Septin-5 Cerebellar Ataxia., PMID:38561872
Neuronal antibodies in nonparaneoplastic autoimmune cerebellar ataxias., PMID:38483149
Neurological autoimmunity in patients with non-pulmonary neuroendocrine neoplasms: clinical manifestations and neural autoantibody profiles., PMID:38466015
Stiff person spectrum disorder diagnosis, misdiagnosis, and suggested diagnostic criteria., PMID:37212351
SARS-CoV-2 antibodies in inflammatory neurological conditions: a multicentre retrospective comparative study., PMID:37171542
Septin-3 autoimmunity in patients with paraneoplastic cerebellar ataxia., PMID:36997937
Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD Panel proposed criteria., PMID:36706773
Downregulation of SEPTIN5 inhibits prostate cancer progression by increasing CD8+ T cell infiltration., PMID:36439885
Septin-5 and -7-IgGs: Neurologic, Serologic, and Pathophysiologic Characteristics., PMID:36053822
Adenylate kinase 5 (AK5) autoimmune encephalitis: Clinical presentations and outcomes in three new patients., PMID:35405429
S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5., PMID:34954322
Diagnostic value of aquaporin-4-IgG live cell based assay in neuromyelitis optica spectrum disorders., PMID:34868626
Autoimmune Septin-5 Disease Presenting as Spinocerebellar Ataxia and Nystagmus., PMID:34031206
Autoimmune movement disorders with neuronal antibodies - an update., PMID:34010219
Positive Predictive Value of Myelin Oligodendrocyte Glycoprotein Autoantibody Testing., PMID:33900394
Autoimmune encephalitis: proposed best practice recommendations for diagnosis and acute management., PMID:33649022
Autoimmune encephalitis: proposed recommendations for symptomatic and long-term management., PMID:33649021
A phenotypically diverse family with an atypical 22q11.2 deletion due to an unbalanced 18q23;22q11.2 translocation., PMID:33569883
Clinical spectrum of high-titre GAD65 antibodies., PMID:33563803
Brainstem and cerebellar involvement in MOG-IgG-associated disorder versus aquaporin-4-IgG and MS., PMID:33372052
Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ., PMID:33203136
MOG-IgG1 and co-existence of neuronal autoantibodies., PMID:32907470
Application of 2015 Seronegative Neuromyelitis Optica Spectrum Disorder Diagnostic Criteria for Patients With Myelin Oligodendrocyte Glycoprotein IgG-Associated Disorders., PMID:32777005
Brain γ-Tocopherol Levels Are Associated with Presynaptic Protein Levels in Elderly Human Midfrontal Cortex., PMID:32741813
Synergistic Neuroprotective Effect of Endogenously-Produced Hydroxytyrosol and Synaptic Vesicle Proteins on Pheochromocytoma Cell Line Against Salsolinol., PMID:32276517
Synaptic mitochondrial dysfunction and septin accumulation are linked to complement-mediated synapse loss in an Alzheimer's disease animal model., PMID:32034429
Autoimmune Vestibulocerebellar Syndromes., PMID:31958862
miR-185 and SEPT5 Genes May Contribute to Parkinson's Disease Pathophysiology., PMID:31814881
Coexistence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4 Antibodies in Adult and Pediatric Patients., PMID:31657826
A revised order of subunits in mammalian septin complexes., PMID:31608568
Synaptotagmin Ca2+ Sensors and Their Spatial Coupling to Presynaptic Cav Channels in Central Cortical Synapses., PMID:30697148
Autoimmune septin-5 cerebellar ataxia., PMID:29998156
Interaction of Recombinant Gallus gallus SEPT5 and Brain Proteins of H5N1-Avian Influenza Virus-Infected Chickens., PMID:28895884
Tpc1 is an important Zn(II)2Cys6 transcriptional regulator required for polarized growth and virulence in the rice blast fungus., PMID:28742127
MLL-SEPT5 Fusion Transcript in Two de novo Acute Myeloid Leukemia Patients With t(11;22)(q23;q11)., PMID:27374720
Septin dynamics are essential for exocytosis., PMID:25575596
Proteomic investigation of the hippocampus in prenatally stressed mice implicates changes in membrane trafficking, cytoskeletal, and metabolic function., PMID:25138076
Differential expression of synaptic proteins in unilateral 6-OHDA lesioned rat model-A comparative proteomics approach., PMID:24841483
Quantification of the brain proteome in Alzheimer's disease using multiplexed mass spectrometry., PMID:24606058
Identification of dynamin as a septin-binding protein., PMID:23260429
Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes., PMID:22665935
Septin 4, the drosophila ortholog of human CDCrel-1, accumulates in parkin mutant brains and is functionally related to the Nedd4 E3 ubiquitin ligase., PMID:22562816
For research use only. Not for human or drug use.
