Catalog No.
EHJ46001
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-His242
Predicted molecular weight
52.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99706
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIR2DL4, KIR-103AS, KIR103AS, CD158d, CD158 antigen-like family member D, CD158D, MHC class I NK cell receptor KIR103AS, Killer cell immunoglobulin-like receptor 2DL4, G9P, Killer cell inhibitory receptor 103AS
Killer Immunoglobulin-Like Receptor 2DL4 (CD158d) Regulates Human Mast Cells both Positively and Negatively: Possible Roles in Pregnancy and Cancer Metastasis., PMID:32023940
Killer cell immunoglobulin-like receptor 2DL4 is expressed in and suppresses the cell growth of Langerhans cell histiocytosis., PMID:28445138
HLA-G1, but Not HLA-G3, Suppresses Human Monocyte/Macrophage-mediated Swine Endothelial Cell Lysis., PMID:27320605
Diagnostic and Biological Significance of KIR Expression Profile Determined by RNA-Seq in Natural Killer/T-Cell Lymphoma., PMID:27060228
The Killer Cell Ig-like Receptor 2DL4 Expression in Human Mast Cells and Its Potential Role in Breast Cancer Invasion., PMID:25735953
Suppression of human macrophage-mediated cytotoxicity by transgenic swine endothelial cell expression of HLA-G., PMID:25559170
TNFR-associated factor 6 and TGF-β-activated kinase 1 control signals for a senescence response by an endosomal NK cell receptor., PMID:24337384
Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses., PMID:24127555
Genetic polymorphism of KIR2DL4 (CD158d), a putative NK cell receptor for HLA-G, does not influence susceptibility to asthma., PMID:24033084
Cellular senescence induced by CD158d reprograms natural killer cells to promote vascular remodeling., PMID:23184984
Ubiquitylation of an internalized killer cell Ig-like receptor by Triad3A disrupts sustained NF-κB signaling., PMID:21270397
Endosomal signaling and a novel pathway defined by the natural killer receptor KIR2DL4 (CD158d)., PMID:20854369
DNA-PKcs controls an endosomal signaling pathway for a proinflammatory response by natural killer cells., PMID:20179272
KIR2DL4 (CD158d) polymorphisms and susceptibility to multiple sclerosis., PMID:19304328
Human leukocyte antigen-G, a ligand for the natural killer receptor KIR2DL4, is expressed by eutopic endometrium only in the menstrual phase., PMID:18314122
Three common alleles of KIR2DL4 (CD158d) encode constitutively expressed, inducible and secreted receptors in NK cells., PMID:17171757
Report of the Wet Workshop for Quantification of Soluble HLA-G in Essen, 2004., PMID:16216668
Cutting edge: KIR2DL4 transduces signals into human NK cells through association with the Fc receptor gamma protein., PMID:15778339
KIR2DL4 is an IL-2-regulated NK cell receptor that exhibits limited expression in humans but triggers strong IFN-gamma production., PMID:14500636
KIR2DL4 (CD158d) genotype influences expression and function in NK cells., PMID:12902476
KIR2DL4 (CD158d), an NK cell-activating receptor with inhibitory potential., PMID:12055234
SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells., PMID:11994457
Cutting edge: induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cells., PMID:11489965
For research use only. Not for human or drug use.
