Catalog No.
YHJ45501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu28-Glu342
Predicted molecular weight
38.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99650
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
OSMRB, IL-31R subunit beta, Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31RB, IL-31R-beta, OSMR, IL-31 receptor subunit beta
PCOS endometrium-derived epithelial organoids as a novel model to study endometrial dysfunction., PMID:40499150
Multi-omics identifies OSM-OSMR as a key receptor-ligand in the tumor environment of endometrial adenocarcinoma., PMID:40450916
Oncostatin-M: a novel leukocyte-derived factor facilitating the ovulatory process in the human ovary., PMID:40327872
Blood-Based Proteomic Profiling Identifies OSMR as a Novel Biomarker of AML Outcomes., PMID:40179376
OSMR induces M2 polarization of glioblastoma associated macrophages through JAK/STAT3 signaling pathway., PMID:40161370
Soluble oncostatin M receptor (sOSMR): A potential biomarker in systemic sclerosis diagnosis., PMID:39894192
Human oncostatin M deficiency underlies an inherited severe bone marrow failure syndrome., PMID:39847438
A Risk Model Based on Ferroptosis-Related Genes OSMR, G0S2, IGFBP6, IGHG2, and FMOD Predicts Prognosis in Glioblastoma Multiforme., PMID:39815665
Upregulation of ABLIM1 Differentiates Intrahepatic Cholangiocarcinoma from Hepatocellular Carcinoma and Both Colorectal and Pancreatic Adenocarcinoma Liver Metastases., PMID:39766812
Integrative analysis of PANoptosis-related genes in diabetic retinopathy: machine learning identification and experimental validation., PMID:39697326
Structures of complete extracellular assemblies of type I and type II Oncostatin M receptor complexes., PMID:39532904
Differential expression of cardiometabolic and inflammation markers and signaling pathways between overweight/obese Qatari adults with high and low plasma salivary α-amylase activity., PMID:39411310
Differential chromatin accessibility and Gene Expression Associated with Backfat Deposition in pigs., PMID:39349998
Diminished expression of the ubiquitin-proteasome system in early treatment-naïve patients with rheumatoid arthritis and concomitant type 2 diabetes may be linked to IL-1 pathway hyper-activity; results from PEAC cohort., PMID:39342401
Thyroid Malignancy and Cutaneous Lichen Amyloidosis: Key Points Amid RET Pathogenic Variants in Medullary Thyroid Cancer/Multiple Endocrine Neoplasia Type 2 (MEN2)., PMID:39337252
Oncostatin M receptor-dependent signaling assessed by RNA sequencing in mouse hematopoietic stem cells., PMID:39266541
Oncostatin M promotes epithelial barrier dysfunction in patients with eosinophilic chronic rhinosinusitis with nasal polyps., PMID:39225375
Benchmark N-glycoproteomics study of common differential tissue and serum N-glycoproteins of patients with hepatocellular carcinoma., PMID:39182988
Screening of novel disease genes of sepsis-induced myocardial Disfunction by RNA sequencing and bioinformatics analysis., PMID:39111545
Suppression of gp130 attenuated insulin-mediated signaling and glucose uptake in skeletal muscle cells., PMID:39080385
The combined inhibition of SLC1A3 and glutaminase in osimertinib-resistant EGFR mutant cells., PMID:39059510
S100A9 as a Key Myocardial Injury Factor Interacting with ATP5 Exacerbates Mitochondrial Dysfunction and Oxidative Stress in Sepsis-Induced Cardiomyopathy., PMID:39006491
Targeted proteomic profiling of cardiogenic shock in the cardiac intensive care unit., PMID:38815149
Prioritizing cervical cancer candidate genes using chaos game and fractal-based time series approach., PMID:38807013
Oncostatin M Induces a Pro-inflammatory Phenotype in Intestinal Subepithelial Myofibroblasts., PMID:38717842
Predictive Model to Identify the Long Time Survivor in Patients with Glioblastoma: A Cohort Study Integrating Machine Learning Algorithms., PMID:38662286
Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR., PMID:38569939
Oncostatin M signaling drives cancer-associated skeletal muscle wasting., PMID:38569555
Nonspecific Inhibition of IL6 Family Cytokine Signalling by Soluble gp130., PMID:38338642
Integrating single-cell and bulk transcriptomic analyses to develop a cancer-associated fibroblast-derived biomarker for predicting prognosis and therapeutic response in breast cancer., PMID:38235137
M1 macrophage-derived oncostatin M induces osteogenic differentiation of ligamentum flavum cells through the JAK2/STAT3 pathway., PMID:38222812
Oncostatin M: Dual Regulator of the Skeletal and Hematopoietic Systems., PMID:38198032
Mechanism and Effect of HNF4α Decrease in a Rat Model of Cirrhosis and Liver Failure., PMID:37993018
Characterization of an Osmr Conditional Knockout Mouse Model., PMID:37961653
Methotrexate for refractory adult atopic dermatitis leads to alterations in cutaneous IL-31 and IL-31RA expression., PMID:37730501
Oncostatin M/Oncostatin M Receptor Signal Induces Radiation-Induced Heart Fibrosis by Regulating SMAD4 in Fibroblast., PMID:37610394
Main active components of Ilex rotunda Thunb. protect against ulcerative colitis by restoring the intestinal mucosal barrier and modulating the cytokine-cytokine interaction pathways., PMID:37541404
Oncostatin-M and OSM-Receptor Feed-Forward Activation of MAPK Induces Separable Stem-like and Mesenchymal Programs., PMID:37310811
EDA2R-NIK signalling promotes muscle atrophy linked to cancer cachexia., PMID:37165186
OSMR deficiency aggravates pressure overload-induced cardiac hypertrophy by modulating macrophages and OSM/LIFR/STAT3 signalling., PMID:37120549
AHNAK, regulated by the OSM/OSMR signaling, involved in the development of primary localized cutaneous amyloidosis., PMID:37100691
Cloning, expression, purification, and immunoblotting analysis of recombinant type III fibronectin domains of human oncostatin M receptor., PMID:36929287
Serum albumin is the strongest predictor of anti-tumor necrosis factor nonresponse in inflammatory bowel disease in resource-constrained regions lacking therapeutic drug monitoring., PMID:36926698
Mirikizumab Regulates Genes Involved in Ulcerative Colitis Disease Activity and Anti-TNF Resistance: Results From a Phase 2 Study., PMID:36881820
Unbiased molecular dynamics simulation of a first-in-class small molecule inhibitor binds to oncostatin M., PMID:36854228
A novel L-phenylalanine dipeptide inhibits prostate cancer cell proliferation by targeting TNFSF9., PMID:36804121
Nanoimmunosensor for the electrochemical detection of oncostatin M receptor and monoclonal autoantibodies in systemic sclerosis., PMID:36706502
Effects of sustained hyperprolactinemia in late gestation on the mammary parenchymal tissue transcriptome of gilts., PMID:36694114
Integration of scRNA-Seq and Bulk RNA-Seq Reveals Molecular Characterization of the Immune Microenvironment in Acute Pancreatitis., PMID:36671463
3D printed Ti-5Cu alloy accelerates osteogenic differentiation of MC3T3-E1 cells by stimulating the M2 phenotype polarization of macrophages., PMID:36275667
For research use only. Not for human or drug use.
