Catalog No.
YHJ44701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu476-Cys713
Predicted molecular weight
30.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99567
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
88 kDa nucleoporin, Nucleoporin Nup88, Nuclear pore complex protein Nup88, NUP88
Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51., PMID:40480227
Nucleoporins shape germ granule architecture and balance small RNA silencing pathways., PMID:40341687
The First Case Report of a Homozygous Consensus Acceptor Splice Variant in the NUP214 Gene Associated With Fetal Hydrops and Arthrogryposis Multiplex., PMID:39650934
Investigating SARS-CoV-2 virus-host interactions and mRNA expression: Insights using three models of D. melanogaster., PMID:38925484
Alteration of actin cytoskeletal organisation in fetal akinesia deformation sequence., PMID:38242956
Overexpressed Nup88 stabilized through interaction with Nup62 promotes NF-κB dependent pathways in cancer., PMID:36845732
Integrative network pharmacology and in silico analyses identify the anti-omicron SARS-CoV-2 potential of eugenol., PMID:36845041
Insights into the role of Nup62 and Nup93 in assembling cytoplasmic ring and central transport channel of the nuclear pore complex., PMID:36222862
Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold., PMID:35679401
Genetic Associations and Differential mRNA Expression Levels of Host Genes Suggest a Viral Trigger for Endemic Pemphigus Foliaceus., PMID:35632621
Glutamine synthetase licenses APC/C-mediated mitotic progression to drive cell growth., PMID:35145325
In focus in HCB., PMID:34729665
Overexpression of the nucleoporin Nup88 stimulates migration and invasion of HeLa cells., PMID:34331103
Exercise training effects on natural killer cells: a preliminary proteomics and systems biology approach., PMID:33965896
A nuclear export sequence promotes CRM1-dependent targeting of the nucleoporin Nup214 to the nuclear pore complex., PMID:33589493
Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts., PMID:33168876
Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants., PMID:32574725
Oncogenic potential of nucleoporins in non-hematological cancers: recent update beyond chromosome translocation and gene fusion., PMID:31654122
XPO1 is a critical player for bortezomib resistance in multiple myeloma: A quantitative proteomic approach., PMID:31465861
The nuclear pore proteins Nup88/214 and T-cell acute lymphatic leukemia-associated NUP214 fusion proteins regulate Notch signaling., PMID:31186352
Pathogenic Variants in NUP214 Cause "Plugged" Nuclear Pore Channels and Acute Febrile Encephalopathy., PMID:31178128
Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence., PMID:30543681
Moonlighting nuclear pore proteins: tissue-specific nucleoporin function in health and disease., PMID:30361777
Integrated network analysis and machine learning approach for the identification of key genes of triple-negative breast cancer., PMID:30302816
TMEM18: A Novel Prognostic Marker in Acute Myeloid Leukemia., PMID:30199869
Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2., PMID:30084827
The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype., PMID:29724197
Nucleoporin NUP88/MOS7 is required for manifestation of phenotypes associated with the Arabidopsis CHITIN ELICITOR RECEPTOR KINASE1 mutant cerk1-4., PMID:28387602
Multiple biological processes may be associated with tumorigenesis under NUP88-overexpressed condition., PMID:27636375
The development of a single molecule fluorescence standard and its application in estimating the stoichiometry of the nuclear pore complex., PMID:27613095
Nucleoporin-Regulated MAP Kinase Signaling in Immunity to a Necrotrophic Fungal Pathogen., PMID:27591188
Can Nup88 expression be associated with atypical endometrial hyperplasia and endometrial cancer? A preliminary study., PMID:26839161
[Interaction of Flightless I with Nup88 and Importin β]., PMID:26762046
Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy., PMID:26731471
Selective Removal of FG Repeat Domains from the Nuclear Pore Complex by Enterovirus 2A(pro)., PMID:26311873
Nucleoporin MOS7/Nup88 is required for mitosis in gametogenesis and seed development in Arabidopsis., PMID:25489100
Cancer and the nuclear pore complex., PMID:24563353
Quantitative regulation of nuclear pore complex proteins by O-GlcNAcylation., PMID:23777819
Mutations that reduce its specific DNA binding inhibit high NaCl-induced nuclear localization of the osmoprotective transcription factor NFAT5., PMID:22992674
Downregulation of nucleoporin 88 and 214 induced by oridonin may protect OCIM2 acute erythroleukemia cells from apoptosis through regulation of nucleocytoplasmic transport of NF-κB., PMID:22824908
[Structure and function of nuclear pore complex]., PMID:22184889
Kinesin-1-mediated capsid disassembly and disruption of the nuclear pore complex promote virus infection., PMID:21925109
Increased serum level of Nup88 protein is associated with the development of colorectal cancer., PMID:21863385
Nucleoporin MOS7/Nup88 contributes to plant immunity and nuclear accumulation of defense regulators., PMID:21327081
The nucleoporin Nup88 is interacting with nuclear lamin A., PMID:21289091
Analyses of porcine public SNPs in coding-gene regions by re-sequencing and phenotypic association studies., PMID:21107721
Nup88 expression is associated with myometrial invasion in endometrial carcinoma., PMID:20973273
Characterization of the role of the tumor marker Nup88 in mitosis., PMID:20497554
Depletion of a single nucleoporin, Nup107, induces apoptosis in eukaryotic cells., PMID:20490895
Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes., PMID:20144761
For research use only. Not for human or drug use.
