Catalog No.
YHJ44001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp189
Predicted molecular weight
22.20 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99497
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Parkinson disease protein 7, Oncogene DJ1, Parkinsonism-associated deglycase, DJ-1, PARK7, Maillard deglycase, Protein/nucleic acid deglycase DJ-1, Protein DJ-1
Reduced DJ-1-F1Fo ATP synthase association correlates with midbrain dopaminergic neuron vulnerability in idiopathic Parkinson's disease., PMID:40479058
The reaction mechanism for glycolysis side product degradation by Parkinson's disease-linked DJ-1., PMID:40464736
Chloroform release from ageing cells andDrosophila DJ-1βmutants., PMID:40456252
An immunoprecipitation-based assay to assess cysteine-106-dependent catalytic activity of human-protein DJ-1 in cell line lysates., PMID:40447250
URB597 downregulates DJ-1 expression in the mouse striatum and induces neurodegeneration., PMID:40373851
Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress., PMID:40360527
[Enriching plasma exosomes for proteomic analysis using a phosphatidylserine-imprinted polymer]., PMID:40331617
Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex., PMID:40327696
Identification and validation of PARK7 as a novel mitochondria-related signature associated with immune microenvironment in asthma., PMID:40319751
PARK7 Is Required to Protect Epithelia Against Damage in Oral Lichen Planus., PMID:40275576
USP7 promotes PINK1/Parkin-dependent mitophagy to ameliorate cerebral ischemia-reperfusion injury by deubiquitinating and stabilizing SIRT1., PMID:40216374
Dipeptidyl peptidase 3 induces myocardial ischemia-reperfusion injury by mediating mitophagy and the intrinsic apoptotic pathway., PMID:40189079
Effect of quercetin on inhibiting gefitinib‑activated non‑small cell lung cancer‑induced cell pyroptosis in cardiomyocytes via modulating mitochondrial autophagy mediated by the SHP2/ROS/AMPK/XBP‑1/DJ‑1 signaling pathway., PMID:40183386
Redox modulatory role of DJ-1 in Parkinson's disease., PMID:40159591
Long-term exposure to PM2.5 exacerbates dopaminergic neuronal loss through CpG hypermethylation induced down-regulation of PINK1 and DJ-1 genes., PMID:40155616
Inhibition of DJ-1 induces TFAM secretion from cancer cells to suppress tumor growth via promoting M1 macrophage polarization., PMID:40147549
Neuronal DJ-1 regulates microglial activation in Parkinson's disease., PMID:40145975
Neuroprotective role and mechanistic insights of DJ-1 dimerization in Parkinson's disease., PMID:40065349
Inhibition of the Parkinson's Disease-Related Protein DJ-1 by Endogenous Neurotoxins of the 1,2,3,4-Tetrahydroisoquinoline Family., PMID:40009035
A PARK7 Mutation-Induced Early-Onset Parkinson's Disease in a Moroccan Family: Expanding the Geographic Spectrum., PMID:39846782
O-GlcNAcylation of DJ-1 suppresses ferroptosis in renal cell carcinoma by affecting the transsulfuration pathway., PMID:39842141
Development and use of DJ-1 affinity microcolumns to screen and study small drug candidates for Parkinson's disease., PMID:39788673
Acetylation-ubiquitination crosstalk of DJ-1 mediates microcalcification formation in diabetic plaques via collagen-matrix vesicles interaction., PMID:39786474
High glucose couples DJ-1 with PTEN to activate PDGFRβ for renal proximal tubular cell injury., PMID:39761275
DJ-1 as a Novel Therapeutic Target for Mitigating Myocardial Ischemia-Reperfusion Injury., PMID:39742003
Short-term effects of retinoic acid on the proliferation of SH-SY5Y cells via mitophagy and apoptosis., PMID:39707779
Intracellular domain of CATSPER1 could serve as a cytoplasmic platform for redox processes in mammalian sperm., PMID:39668395
DJ-1-mediated repression of the RNA-binding protein FMRP is predicted to impact known Alzheimer's disease-related protein networks., PMID:39610285
Modifications of DJ-1 in which pI shifts to acidic in red blood cells a potential biomarker for Parkinson's disease at early stages., PMID:39576630
Ferulic Acid Interferes with Radioactive Intestinal Injury Through the DJ-1-Nrf2 and Sirt1-NF-κB-NLRP3 Pathways., PMID:39519712
The dual role of methylglyoxal in plant stress response and regulation of DJ-1 protein., PMID:39508129
STUB1 suppresses paclitaxel resistance in ovarian cancer through mediating HOXB3 ubiquitination to inhibit PARK7 expression., PMID:39501077
The Parkinson's disease DJ-1/PARK7 gene controls peripheral neuronal excitability and painful neuropathy., PMID:39486088
Peptide Activator Stabilizes DJ-1 Structure and Enhances Its Activity., PMID:39456860
Mesenchymal stromal cells deliver H2S-enhanced Nrf2 via extracellular vesicles to mediate mitochondrial homeostasis for repairing hypoxia-ischemia brain damage., PMID:39427747
A Review on the Role of SNCA Gene in Neurodegenerative Diseases., PMID:39411638
Parkinson biomarker determination with an Au microflower-enhanced electrochemical immunosensor using non-Faradaic capacitance measurements., PMID:39392501
Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and colocalization analysis., PMID:39351539
DJ-1 regulates astrocyte activation through miR-155/SHP-1 signaling in cerebral ischemia/reperfusion injury., PMID:39323054
Potentially functional variants of PARK7 and DDR2 in ferroptosis-related genes predict survival of non-small cell lung cancer patients., PMID:39319523
Upregulation of EFCAB7 after radiofrequency ablation promoting hepatocellular carcinoma metastasis and survival by regulating PARK7., PMID:39276379
USP19 exerts a tumor-promoting role in diffuse large B cell lymphoma through stabilizing PARK7., PMID:39240655
Betulin ameliorates neuronal apoptosis and oxidative injury via DJ-1/Akt/Nrf2 signaling pathway after subarachnoid hemorrhage., PMID:39238115
DJ-1: Potential target for treatment of myocardial ischemia-reperfusion injury., PMID:39232383
Genetic and clinical study of PARK7 in Japanese Parkinson's disease., PMID:39170205
Retinitis pigmentosa in DJ1- associated early-onset Parkinson's disease: A phenotypic expansion., PMID:39168074
Genetic profiles of multiple system atrophy revealed by exome sequencing, long-read sequencing and spinocerebellar ataxia repeat expansion analysis., PMID:39152783
Effects of Premortem Stress on Protein Expression, Steak Color, Oxidation, and Myofibrillar Fragmentation Index in the Longissimus Lumborum., PMID:39123696
cPGA hydrolase assay of DJ-1 in crude cell lysates: Implications for sensing of oxidative stress., PMID:39084336
For research use only. Not for human or drug use.
