Catalog No.
YHJ40801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys157-Gly390
Predicted molecular weight
27.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96MU8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dickkopf receptor, Kringle-containing protein marking the eye and the nose, Kringle domain-containing transmembrane protein 1, KREMEN1, Kremen protein 1, KREMEN, KRM1
Molecularly distinct striatonigral neuron subtypes differentially regulate locomotion., PMID:40108161
Construction of a Vero cell line expression human KREMEN1 for the development of CVA6 vaccines., PMID:39825444
Completely conserved VP2 residue K140 of KREMEN1-dependent enteroviruses is critical for virus-receptor interactions and viral infection., PMID:39817751
DKK1 and Its Receptors in Esophageal Adenocarcinoma: A Promising Molecular Target., PMID:39795613
Efficacy of CBP/p300 Dual Inhibitors against Derepression of KREMEN2 in cBAF-Deficient Cancers., PMID:39625239
Exploration of potential drug targets for Glaucoma by plasma proteome screening., PMID:39342991
Patch and matrix striatonigral neurons differentially regulate locomotion., PMID:38978598
Noncoding RNA regulates the expression of Krm1 and Dkk2 to synergistically affect aortic valve lesions., PMID:38945954
Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics., PMID:38902252
Targeting dependency on a paralog pair of CBP/p300 against de-repression of KREMEN2 in SMARCB1-deficient cancers., PMID:38839769
Multi-omics analysis reveals COVID-19 vaccine induced attenuation of inflammatory responses during breakthrough disease., PMID:38649734
Identification of receptors and factors associated with human coronaviruses in the oral cavity using single-cell RNA sequencing., PMID:38560173
High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma., PMID:38272457
Senescence-Targeted and NAD+-Dependent SIRT1-Activated Nanoplatform to Counteract Stem Cell Senescence for Promoting Aged Bone Regeneration., PMID:37948437
Identification of Critical Amino Acids of Coxsackievirus A10 Associated with Cell Tropism and Viral RNA Release during Uncoating., PMID:37896891
VP2 residue N142 of coxsackievirus A10 is critical for the interaction with KREMEN1 receptor and neutralizing antibodies and the pathogenicity in mice., PMID:37788227
Presence of KREMEN receptors for DKK1 in the preimplantation bovine embryo., PMID:37582174
A WNT4- and DKK3-driven canonical to noncanonical Wnt signaling switch controls multiciliogenesis., PMID:37505110
Human SCARB2 Acts as a Cellular Associator for Helping Coxsackieviruses A10 Infection., PMID:37112912
SARS-CoV-2 Receptors and Their Involvement in Cell Infection., PMID:37008884
Dual blockages of a broad and potent neutralizing IgM antibody targeting GH loop of EV-As., PMID:36726218
Comprehensive analysis of SARS-CoV-2 receptor proteins in human respiratory tissues identifies alveolar macrophages as potential virus entry site., PMID:36700825
ACE2-Independent Alternative Receptors for SARS-CoV-2., PMID:36423144
An improved Fuzzy based GWO algorithm for predicting the potential host receptor of COVID-19 infection., PMID:36334362
SARS-CoV-2 cell entry beyond the ACE2 receptor., PMID:35754059
DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation., PMID:35658977
Circ_0003611 acts as a miR-885-5p sponge to aggravate the amyloid-β-induced neuronal injury in Alzheimer's disease., PMID:35076819
Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1., PMID:34903854
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2., PMID:34837059
Synergistic Mutations of LRP6 and WNT10A in Familial Tooth Agenesis., PMID:34834569
MCPIP1 inhibits Wnt/β-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs., PMID:34657130
Novel homozygous KREMEN1 mutation causes ectodermal dysplasia., PMID:34028942
The Effect of hsa-miR-451b Knockdown on Biological Functions of Gastric Cancer Stem-Like Cells., PMID:33725258
Assessment of Wnt pathway selected gene expression levels in peripheral blood mononuclear cells (PBMCs) of postmenopausal patients with low bone mass., PMID:33357212
Tooth agenesis: What do we know and is there a connection to cancer?, PMID:33249565
WNT Signaling Driven by R-spondin 1 and LGR6 in High-grade Serous Ovarian Cancer., PMID:33109540
Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1., PMID:32690697
Rac1-dependent endocytosis and Rab5-dependent intracellular trafficking are required by Enterovirus A71 and Coxsackievirus A10 to establish infections., PMID:32560826
Replication of 15 loci involved in human plasma protein N-glycosylation in 4802 samples from four cohorts., PMID:32521004
DKK3 attenuates JNK and AP-1 induced inflammation via Kremen-1 and DVL-1 in mice following intracerebral hemorrhage., PMID:32331523
Expression of genes involved in apoptosis is dysregulated in mucopolysaccharidoses as revealed by pilot transcriptomic analyses., PMID:32125037
Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10., PMID:31911601
Knockdown of lncRNA SNHG1 attenuated Aβ25-35-inudced neuronal injury via regulating KREMEN1 by acting as a ceRNA of miR-137 in neuronal cells., PMID:31447119
Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts., PMID:30631061
Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating., PMID:30478256
Genetic analysis: Wnt and other pathways in nonsyndromic tooth agenesis., PMID:29969831
Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins., PMID:29925589
DKK1 and Kremen Expression Predicts the Osteoblastic Response to Bone Metastasis., PMID:29772510
KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses., PMID:29681460
Novel compound heterozygous mutations in KREMEN1 confirm it as a disease gene for ectodermal dysplasia., PMID:29526031
For research use only. Not for human or drug use.
