Catalog No.
YHJ39301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Ser103
Predicted molecular weight
13.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96FQ6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
S100A16, Aging-associated gene 13 protein, Protein S100-A16, S100 calcium-binding protein A16, S100F, Protein S100-F
S100 A16 promotes the progression of osteosarcoma by activating the PI3 K/AKT signaling pathway through ANXA2., PMID:40481236
Identification of the molecular subtype and prognostic characteristics of lung adenocarcinoma based on CD8+ T cell-related gene signature., PMID:40095496
VDAC1-NF-κB/p65-mediated S100A16 contributes to myocardial ischemia/reperfusion injury by regulating oxidative stress and inflammatory response via calmodulin/CaMKK2/AMPK pathway., PMID:39613175
Unveiling the pan-cancer landscape of S100A16: A comprehensive analysis of prognostic significance, drug sensitivity, and immunomodulatory roles., PMID:39465820
S100A16 stabilizes the ITGA3‑mediated ECM‑receptor interaction pathway to drive the malignant properties of lung adenocarcinoma cells via binding MOV10., PMID:39450567
Icariside II protects from marrow adipose tissue (MAT) expansion in estrogen-deficient mice by targeting S100A16., PMID:39101576
Resistance to gemcitabine is mediated by the circ_0036627/miR-145/S100A16 axis in pancreatic cancer., PMID:38924205
Potential drug targets for tumors identified through Mendelian randomization analysis., PMID:38762700
S100A16 is a potential target for reshaping the tumor microenvironment in the hypoxic context of liver cancer., PMID:38733818
HIF-1α participates in the regulation of S100A16-HRD1-GSK3β/CK1α pathway in renal hypoxia injury., PMID:38710691
S100 calcium‑binding protein A16 suppresses the osteogenic differentiation of rat bone marrow mesenchymal stem cells by inhibiting SMAD family member 4 signaling., PMID:38682113
SPDEF drives pancreatic adenocarcinoma progression via transcriptional upregulation of S100A16 and activation of the PI3K/AKT signaling pathway., PMID:38520747
Expression and gene regulatory network of S100A16 protein in cervical cancer cells based on data mining., PMID:37978469
S100A16 cooperates with DEPDC1 to promote the progression and angiogenesis of nephroblastoma through PI3K/Akt/mTOR pathway., PMID:37955537
S100a16 Deficiency Prevents Alcohol-induced Fatty Liver Injury via Inducing MANF Expression in Mice., PMID:37928262
Expression of S100A16 Is Associated with Biological Aggressiveness and Poor Prognosis in Patients with Bladder Cancer Who Underwent Radical Cystectomy., PMID:37833982
Identification of circRNA-lncRNA-miRNA-mRNA competitive endogenous RNA networks as prognostic bio-markers in head and neck squamous cell carcinoma., PMID:37522233
An Update on S100A16 in Human Cancer., PMID:37509106
Identification of Biomarkers Affecting Cryopreservation Recovery Ratio in Ram Spermatozoa Using Tandem Mass Tags (TMT)-Based Quantitative Proteomics Approach., PMID:37508145
Loss of ZNF148 enhances insulin secretion in human pancreatic β cells., PMID:37288664
S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development., PMID:37151881
[Changes in Expression of Genes Associated with Calcium Processes in the Hippocampus in Mice Exposed to Chronic Social Stress]., PMID:37000665
miR-508-5p serves as an anti-oncogene by targeting S100A16 to regulate AKT signaling and epithelial-mesenchymal transition process in lung adenocarcinoma cells., PMID:36967030
New progress with calcium-binding protein S100A16 in digestive system disease., PMID:36718596
Circular ribonucleic acid circ-FADS2 promotes colorectal cancer cell proliferation and invasion by regulating miR-498/S100A16., PMID:36696241
Construction of noninvasive prognostic model of bladder cancer patients based on urine proteomics and screening of natural compounds., PMID:36562811
An inhibitor of BRD4, GNE987, inhibits the growth of glioblastoma cells by targeting C-Myc and S100A16., PMID:36224471
Calbindin S100A16 Promotes Renal Cell Carcinoma Progression and Angiogenesis via the VEGF/VEGFR2 Signaling Pathway., PMID:36176934
An immune-related gene prognostic risk index for pancreatic adenocarcinoma., PMID:35958614
S100a16 deficiency prevents hepatic stellate cells activation and liver fibrosis via inhibiting CXCR4 expression., PMID:35914619
Characterizing molecular subtypes of high-risk non-muscle-invasive bladder cancer in African American patients., PMID:35618577
S100A16 promotes acute kidney injury by activating HRD1-induced ubiquitination and degradation of GSK3β and CK1α., PMID:35279748
Analysis of the tumor immune environment identifies an immune gene set-based prognostic signature in non-small cell lung cancer., PMID:35242860
Downregulated Calcium-Binding Protein S100A16 and HSP27 in Placenta-Derived Multipotent Cells Induce Functional Astrocyte Differentiation., PMID:35061207
Identification and functional analysis of novel oncogene DDX60L in pancreatic ductal adenocarcinoma., PMID:34789165
Calcium Binding Protein S100A16 Expedites Proliferation, Invasion and Epithelial-Mesenchymal Transition Process in Gastric Cancer., PMID:34650982
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis., PMID:34645789
Integrative analysis of transcriptome-wide association study and mRNA expression profile identified candidate genes and pathways associated with aortic aneurysm and dissection., PMID:34626721
Comprehensive analysis of the transcriptional expressions and prognostic value of S100A family in pancreatic ductal adenocarcinoma., PMID:34530774
Integrated analysis identifies S100A16 as a potential prognostic marker for pancreatic cancer., PMID:34150181
S100A gene family: immune-related prognostic biomarkers and therapeutic targets for low-grade glioma., PMID:34148033
Proteomic Profile of Saliva in Parkinson's Disease Patients: A Proof of Concept Study., PMID:34070185
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-κB Pathway in Human Gastric Cancer., PMID:33921267
Expressional and Prognostic Value of S100A16 in Pancreatic Cancer Via Integrated Bioinformatics Analyses., PMID:33912559
Prognostic values and immune suppression of the S100A family in pancreatic cancer., PMID:33580614
Interference of S100A16 suppresses lipid accumulation and inflammation in high glucose-induced HK-2 cells., PMID:33389513
S100A16 promotes metastasis and progression of pancreatic cancer through FGF19-mediated AKT and ERK1/2 pathways., PMID:33389337
S100A16 induces epithelial-mesenchymal transition in human PDAC cells and is a new therapeutic target for pancreatic cancer treatment that synergizes with gemcitabine., PMID:33359364
S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway., PMID:33355370
Comprehensive analysis of the expression and prognosis for S100 in human ovarian cancer: A STROBE study., PMID:33217795