Catalog No.
YHJ38001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser31-Lys243
Predicted molecular weight
25.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96CG8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collagen triple helix repeat-containing protein 1, CTHRC1
Diagnostic accuracy of serum biomarkers MMP11 and SPP1 in non-small cell lung cancer: an analysis of sensitivity, specificity, and area under the curve., PMID:40386736
A novel Wnt/β-catenin signaling gene signature for progression and metastasis of gastric cancer., PMID:40296906
CTHRC1: a key player in colorectal cancer progression and immune evasion., PMID:40201173
Single-cell and transcriptome analyses revealed CTHRC1 a potential therapeutic target mediating invasion and tumor microenvironment in TNBC: experimental validation., PMID:40134434
CTHRC1 Expression Results in Secretion-Mediated, SOX9-Dependent Suppression of Adipogenesis: Implications for the Regulatory Role of Newly Identified CTHRC1+/PDGFR-Alpha+ Stromal Cells of Adipose., PMID:40076432
Single-cell and spatial transcriptome profiling reveal CTHRC1+ fibroblasts promote EMT through WNT5A signaling in colorectal cancer., PMID:40050872
Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes., PMID:40032993
Cancer-associated fibroblasts promote EGFR-TKI resistance via the CTHRC1/glycolysis/H3K18la positive feedback loop., PMID:40011576
CTHRC1 expresses in cancer-associated fibroblasts and is associated with resistance to anti-androgen therapy in prostate cancer., PMID:40009323
KDM6B preferentially promotes bone formation over resorption to facilitate postnatal bone mass accrual through collagen triple helix repeat containing 1-mediated PKCδ/MAPKs signaling., PMID:39961019
RUNX2 promotes fibrosis via an alveolar-to-pathological fibroblast transition., PMID:39910313
Enter the Matrix: Fibroblast-immune cell interactions shape extracellular matrix deposition in health and disease., PMID:39886650
Expression and role of CTHRC1 in inflammatory bowel disease in children., PMID:39867826
Aberrant promoter methylation of CTHRC1 gene and its clinicopathological characteristics in head and neck cancer., PMID:39863454
Piezo2 Is a Key Mechanoreceptor in Lung Fibrosis that Drives Myofibroblast Differentiation., PMID:39855300
Orchestrated response from heterogenous fibroblast subsets contributes to repair from surgery-induced stress after airway reconstruction., PMID:39836476
Non-canonical Wnt signaling pathway activated NFATC3 promotes GDF15 expression in MASH: prospective analyses of UK biobank proteomic data., PMID:39836348
Deep multi-omics integration approach reveals new molecular features of uterine leiomyosarcoma., PMID:39708976
TFAP2A activates CTHRC1 to influence the migration of lung adenocarcinoma cells by modulating fatty acid metabolism., PMID:39681283
The impact of POSTN on tumor cell behavior and the tumor microenvironment in lung adenocarcinoma., PMID:39672019
Targeting the Epigenetic Regulator CBX5 Promotes Fibroblast Metabolic Reprogramming and Inhibits Lung Fibrosis., PMID:39642371
Comprehensive RNA Sequencing Analysis Identifies Network Hub Genes and Biomarkers Differentiating Desmoid-type Fibromatosis From Reactive Fibrosis., PMID:39617099
Key Proteins for Regeneration in A. mexicanum: Transcriptomic Insights From Aged and Juvenile Limbs., PMID:39575453
CTHRC1 Attenuates Tendinopathy via Enhancing EGFR/MAPK Signaling Pathway., PMID:39540237
WTAP promotes laryngeal carcinoma cell progression by posttranscriptional activation of CTHRC1 in an m6A-YTHDF1-dependent way., PMID:39435427
Exosomal CTHRC1 from cancer-associated fibroblasts facilitates endometrial cancer progression via ITGB3/FAK signaling pathway., PMID:39229506
Machine learning approach to predict blood-secretory proteins and potential biomarkers for liver cancer using omics data., PMID:39216516
Serum protein responses to Dietary Approaches to Stop Hypertension (DASH) and DASH-Sodium trials and associations with blood pressure changes., PMID:39196693
Single-cell RNA sequencing reveals the CRTAC1+ population actively contributes to the pathogenesis of spinal ligament degeneration by SPP1+ macrophage., PMID:39158018
CTHRC1 modulates cell proliferation and invasion in hepatocellular carcinoma by DNA methylation., PMID:39134747
Diagnostic biomarkers in knee osteoarthritis: Based on bioinformatics and experimental verification in vivo and in vitro., PMID:39110784
Screening of key modules and key genes in the prevention of skin cancer development based on gene volcano plot and WGCNA., PMID:39073152
CTHRC1 is associated with BRAF(V600E) mutation and correlates with prognosis, immune cell infiltration, and drug resistance in colon cancer, thyroid cancer, and melanoma., PMID:39052013
CTHRC1 serves as an indicator in biliary atresia for evaluating the stage of liver fibrosis and predicting prognosis., PMID:39043537
CTHRC1 is a prognostic biomarker correlated with immune infiltration in head and neck squamous cell carcinoma., PMID:38937712
CTHRC1: An Emerging Hallmark of Pathogenic Fibroblasts in Lung Fibrosis., PMID:38891078
The role and molecular mechanism of CTHRC1 in fibrosis., PMID:38834096
The concept of Sfrp1+ transitional fibroblasts: the key to dissociating lineage heterogeneity and fate of invasive fibroblasts in pulmonary fibrosis?, PMID:38724178
Collagen Triple Helix Repeat-Containing Protein 1 Is a Novel Biomarker of Right Ventricular Involvement in Pulmonary Hypertension., PMID:38692430
The role of collagen triple helix repeat containing 1 (CTHRC1) in cancer development and progression., PMID:38686865
The impact of SOX4-activated CTHRC1 transcriptional activity regulating DNA damage repair on cisplatin resistance in lung adenocarcinoma., PMID:38629299
Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes., PMID:38460933
Platelets modulate cardiac remodeling via the collagen receptor GPVI after acute myocardial infarction., PMID:38274818
Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts., PMID:38212077
Activated CTHRC1 promotes glycolysis in endothelial cells: Implications for metabolism and angiogenesis., PMID:38040222
CTHRC1 promotes colorectal cancer progression by recruiting tumor-associated macrophages via up-regulation of CCL15., PMID:37987774
Potential Common Molecular Mechanisms Between Periodontitis and Hepatocellular Carcinoma: A Bioinformatic Analysis and Validation., PMID:37889061
Mesenchymal Stromal Cell Secretome Is Affected by Tissue Source and Donor Age., PMID:37591507
Integrated analysis of single cell and bulk RNA sequencing identifies CTHRC1+ INHBA+ CAF as drivers of colorectal cancer progression., PMID:37539967
CTHRC1 Induces Pancreatic Stellate Cells (PSCs) into Myofibroblast-like Cancer-Associated Fibroblasts (myCAFs)., PMID:37444482
For research use only. Not for human or drug use.
