Catalog No.
YHJ33701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg70
Predicted molecular weight
34.17 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92847
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 5% Trehalose, 2% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ghrelin receptor, GHSR, GHRP, GH-releasing peptide receptor, Growth hormone secretagogue receptor type 1, GHS-R
Note
For research use only.
Investigation of the association between therapeutic effectiveness of anamorelin and Glasgow prognostic score in patients with cancer cachexia: a competing risk analysis., PMID:39789368
Ghrelin Promotes Lipid Uptake into White Adipose Tissue via Endothelial Growth Hormone Secretagogue-Receptor in Mice., PMID:39796581
Real-time detection of somatostatin release from single islets reveals hypersecretion in type 2 diabetes., PMID:39803760
Intranasal Delivery of a Ghrelin Mimetic Engages the Brain Ghrelin Signaling System in Mice., PMID:39813130
Critical Insights Into LEAP2 Biology and Physiological Functions: Potential Roles Beyond Ghrelin Antagonism., PMID:39823403
Ghrelin promotes chronic diabetic wound healing by regulating keratinocyte proliferation and migration through the ERK1/2 pathway., PMID:39824309
The structure and function of the ghrelin receptor coding for drug actions., PMID:39833471
Peptide with Dual Roles in Immune and Metabolic Regulation: Liver-Expressed Antimicrobial Peptide-2 (LEAP-2)., PMID:39860298
Ghrelin suppresses water intake with a different physiological significance from atrial natriuretic peptide in conscious seawater-acclimated eels., PMID:39882695
Tryptophan-sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin-producing cells., PMID:39888273
G protein peptidomimetics reveal allosteric effects and stepwise interactions in ghrelin receptor-G protein coupling., PMID:39903809
Novel chimeric peptides of endomorphin-2 and the active fragments of ghrelin exhibit blood-brain barrier permeability and central antinociceptive effects with reduced opioid-related side effects., PMID:39904410
Ghrelin's modulation of growth hormone secretagogue receptors in primary glioblastoma and meningioma: A comprehensive in-vitro study., PMID:39914147
Antimicrobial Neuropeptides and Their Receptors: Immunoregulator and Therapeutic Targets for Immune Disorders., PMID:39942672
The role of leptin and ghrelin in the regulation of appetite in obesity., PMID:39983918
Fructose induces inflammatory activation in macrophages and microglia through the nutrient-sensing ghrelin receptor., PMID:39985299
Anamorelin Efficacy in Non-Small-Cell Lung Cancer Patients With Cachexia: Insights From ROMANA 1 and ROMANA 2., PMID:39992021
Naringenin Decreases Retroperitoneal Adiposity and Improves Metabolic Parameters in a Rat Model of Western Diet-Induced Obesity., PMID:39997735
A Modular Customizable Ligand-Conjugate (LC) System Targeting Ghrelin O-Acyltransferase., PMID:40001510
Environmental enrichment attenuates reinstatement of heroin seeking and reverses heroin-induced upregulation of mesolimbic ghrelin receptors., PMID:40022817
Physiological roles of ghrelin in the regulation of gastrointestinal motility in vertebrates., PMID:40024446
Regulation of LEAP2 by insulin and glucagon in mice and humans., PMID:40056903
GHSR gene knockout alleviates the liver pathological response in Echinococcus granulosus infection by reducing parasite survival., PMID:40065480
Characterization of Leptin and Leptin Receptor Gene in the Siberian Sturgeon (Acipenser baerii): Molecular Cloning, Tissue Distribution, and Its Involvement in Feeding Regulation., PMID:40076594
Stress-induced GHS-R1a expression in medial prefrontal cortical neurons promotes vulnerability to anxiety in mice., PMID:40082560
The effect of garlic and stevia extract with aerobic exercise on hypothalamic leptin and ghrelin receptor mRNA expression and insulin resistance in obese rats., PMID:40087612
Midbrain ghrelin receptor signalling regulates binge drinking in a sex specific manner., PMID:40089486
Design, Biological Characterization, and Discovery of Capromorelin Derivatives as Oral Growth Hormone Secretagogue Receptor Type 1a Agonist for the Treatment of Growth Hormone Deficiency., PMID:40091212
Evidence for independent actions of the CRF and ghrelin systems in binge-like alcohol drinking in mice., PMID:40139339
Elevation of ghrelin by B-adrenergic activation is independent of glucose variations and feeding regimen in the rat., PMID:40169505
Comprehensive insights into emerging advances in the Neurobiology of anorexia., PMID:40180244
The relationship between ghrelin, epilepsy-related inflammatory biomarkers (IL-1β, IL-1R1, HMGB1), and drug-resistant epilepsy in children., PMID:40185046
The Pathologic Roles and Therapeutic Implications of Ghrelin/GHSR System in Mental Disorders., PMID:40226675
Altered circadian pattern of activity in a chronic activity-based anorexia nervosa-like female mouse model deficient for GHSR., PMID:40245654
Atypical presentation of pseudohypoparathyroidism with absence of mutations in the GNAS gene: a case report., PMID:40251565
Unveiling G-Protein-Coupled Receptor Conformational Dynamics via Metadynamics Simulations and Markov State Models., PMID:40272908
GHS-R1a signaling drives anxiety-related behavior by shaping excitability of ventromedial hypothalamic neurons., PMID:40274845
Ghrelin/GHSR system attenuates collagen-induced arthritis in mice and ameliorates inflammation in human rheumatoid arthritis fibroblast-like synoviocytes., PMID:40339721
Role of rs490683 variant in the promoter region of the ghrelin receptor gene on body weight and metabolic syndrome after a partial meal replacement hypocaloric diet., PMID:40347908
Goldfish phoenixin: (I) structural characterization, tissue distribution, and novel function as a feedforward signal for feeding-induced food intake in fish model., PMID:40365230
Effects of cholinergic antagonists on ghrelin release and expression in the crop, proventriculus, and duodenum of newly hatched chickens., PMID:40386621
The nose knows: Olfaction as a metabolic gatekeeper in health and disease., PMID:40408280
Optogenetic activation of hypothalamic AgRP neurons in transgenic zebrafish larvae increased food intake., PMID:40410389
[Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism]., PMID:40418135
The correlation between obesity and leptin signaling pathways., PMID:40424747
Constitutive ghrelin receptor activity enables reversal of dopamine D2 receptor signaling., PMID:40441153
Lipids modulate the dynamics of GPCR:β-arrestin interaction., PMID:40442125
The Connection Between the Appetite-Regulatory Peptides Ghrelin and GLP-1 and Alcohol Use Disorder., PMID:40442388
GHSR-Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation., PMID:40479577
What's in your plate?AMPA receptors modulation at the crossroads of homeostatic and hedonic eating., PMID:40484361
For research use only. Not for human or drug use.
