Catalog No.
YHJ33401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu67-Thr172
Predicted molecular weight
14.55 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92819
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HA synthase 2, Hyaluronan synthase 2, Hyaluronic acid synthase 2, HAS2, Hyaluronate synthase 2
CD44-downregulation in multiple myeloma inhibits cytoskeleton rearrangement through actin depolymerization., PMID:40481899
Genetic Determinants of Colonic Diverticulosis-A Systematic Review., PMID:40428403
Exosomes derived from adipose-derived stem cells alleviate acute radiation-induced dermatitis through up-regulating hyaluronic acid synthase 1 expression., PMID:40394699
The alleviating effect of Bai-Ju essence on atopic dermatitis through anti-inflammatory and skin barrier repair mechanisms., PMID:40394445
Expression and molecular characterization of an intriguing hyaluronan synthase (HAS) from the symbiont "Candidatus Mycoplasma liparidae" in snailfish., PMID:40297469
Piezo1-Mediated Calcium Flux Transfers Mechanosignal to Yes-Associated Protein to Stimulate Matrix Production in Keloid., PMID:40254148
Study on Moisturizing Effect of Dendrobium officinale, Sparassis crispa, and Their Compound Extracts., PMID:40247751
Prognostic value of a combination of cardiac biomarkers and risk indices for major adverse cardiovascular events following non-cardiac surgery in geriatric patients: a prospective cohort study., PMID:40246864
Hyaluronan network remodeling by ZEB1 and ITIH2 enhances the motility and invasiveness of cancer cells., PMID:40178908
In Vitro and In Vivo Evaluation of an Emollient-Rich Moisturizer Developed to Address Three Critical Elements of Natural Moisturization., PMID:40176773
Determination via an Integration Strategy of the Potential Dermal ECM Reconstruction Mechanism by Which the WAW Formula Alleviates Skin Aging., PMID:40160145
The Interaction Between the asb5a and asb5b Subtypes Jointly Regulates the L-R Asymmetrical Development of the Heart in Zebrafish., PMID:40141403
Effects of natural killer cell‑conditioned medium on UVB‑induced photoaging in human keratinocytes and a human reconstructed skin model., PMID:40084708
Extracellular matrix dynamics in a rat model of pulmonary arterial hypertension: unveiling the role of hyaluronan in disease pathology., PMID:40079867
Increased HA/CD44/TGFβ signaling implicates in renal fibrosis of a Col4a5 mutant Alport mice., PMID:40075271
Hyaluronic acid-based hydrogels modulate neuroinflammation and extracellular matrix remodelling in multiple sclerosis: insights from a primary cortical cell model., PMID:40067190
4-Methylumbelliferone, an Inhibitor of Hyaluronan Synthase, Prevents the Development of Oncological, Inflammatory, Degenerative, and Autoimmune Diseases., PMID:40058970
pH-Responsive Engineered Exosomes Enhance Endogenous Hyaluronan Production by Reprogramming Chondrocytes for Cartilage Repair., PMID:40042438
Regulating cellular metabolism and morphology to achieve high-yield synthesis of hyaluronan with controllable molecular weights., PMID:40021631
Promegestone Prevents Lipopolysaccharide-Induced Cervical Remodeling in Pregnant Mice., PMID:39996716
Metastatic tumor growth in steatotic liver is promoted by HAS2-mediated fibrotic tumor microenvironment., PMID:39946200
Sargassum plagiophyllum Ethanolic Extract Enhances Wound Healing by Modulating FAK/Src/Akt/p38 and Rac1 Signaling in Keratinocytes HaCaT Cells., PMID:39886257
Activated cardiac fibroblasts are a primary source of high-molecular-weight hyaluronan production., PMID:39871135
Heart Morphogenesis Requires Smyd1b for Proper Incorporation of the Second Heart Field in Zebrafish., PMID:39858599
Cadmium promotes hyaluronan synthesis by inducing hyaluronan synthase 3 expression in cultured vascular endothelial cells via the c-Jun N-terminal kinase-c-Jun pathway., PMID:39837363
Comments about the comparative bulk RNA sequencing between palmoplantar pustulosis and dyshidrotic palmoplantar eczema., PMID:39810849
Hyaluronic acid promotes hepatocellular carcinoma proliferation by upregulating CD44 expression and enhancing glucose metabolism flux., PMID:39798466
Targeting hyaluronan synthesis enhances the therapeutic effectiveness of biologics in inflammatory bowel disease., PMID:39782690
Differential Regulation of Hyaluronan Synthesis by Three Isoforms of Hyaluronan Synthases in Mammalian Cells., PMID:39766274
Hyaluronan Directs Alveolar Type II Cell Response to Acute Ozone Exposure in Mice., PMID:39761597
Bone quality relies on hyaluronan synthesis - Insights from mice with complete knockout of hyaluronan synthase expression., PMID:39736893
Limosilactobacillus fermentum MG5368 and Lactiplantibacillus plantarum MG989 Regulates Skin Health in UVB-Induced HaCaT Cells and Hairless Mice Model., PMID:39683478
Gain-of-Function Chromatin Remodeling Activity of Oncogenic FOXL2C134W Reprograms Glucocorticoid Receptor Occupancy to Drive Granulosa Cell Tumors., PMID:39652611
Tanshinone IIA Protects Ischemia/Reperfusion-Induced Cardiomyocyte Injury by Inhibiting the HAS2/FGF9 Axis., PMID:39568660
Characteristics of Hyaluronan Metabolism During Myofibroblast Differentiation in Orbital Fibroblasts., PMID:39504052
Potential Skin Health Benefits of Abalone By-Products Suggested by Their Effects on MAPKS and PI3K/AKT/NF-kB Signaling Pathways in HDF and HaCaT Cells., PMID:39335831
Anionic cardiolipin stabilizes the transmembrane region of hyaluronan synthase and promotes catalysis-relevant dynamics., PMID:39332577
Structural insights into translocation and tailored synthesis of hyaluronan., PMID:39322765
SARS-CoV-2 infection induces hyaluronan production in vitro and hyaluronan levels in COVID-19 patients relate to morbidity and long-term lung impairment: a prospective cohort study., PMID:39302125
A point-of-research decision in synovial tissue engineering: Mesenchymal stromal cells, tissue derived fibroblast or CTGF-mediated mesenchymal-to-fibroblast transition., PMID:39293131
TGF-β and RAS jointly unmask primed enhancers to drive metastasis., PMID:39243762
Short-Term and Long-Term Fluvastatin Inhibit Effects of Thrombospondin-1 on Human Vascular Smooth Muscle Cells., PMID:39235354
Identification and functional validation of miR-190b-5p and miR-296-3p as novel therapeutic attenuators of liver fibrosis., PMID:39218230
Efficacy of Vitamin B12 and Adenosine Triphosphate in Enhancing Skin Radiance: Unveiled with a Drug-Target Interaction Deep Learning-Based Model., PMID:39194754
RNAseq of Gingival Fibroblasts Exposed to PRF Membrane Lysates and PRF Serum., PMID:39120336
Precision medicine in lupus nephritis., PMID:39068963
Wrinkle-Improving Effect of Novel Peptide That Binds to Nicotinic Acetylcholine Receptor., PMID:39063099
Nitrilotriacetic Acid Functionalized Microgels for Efficient Immobilization of Hyaluronan Synthase., PMID:39018489
Apple Pomace Extract Induces Cell Proliferation and Increases Type I Collagen and Hyaluronan Production in Human Skin Fibroblasts In Vitro., PMID:39001986
Evidence of Urtica dioica Agglutinin's Antiproliferative and Anti-migratory Potentials on the Hyaluronic Acid-Overexpressing Prostate Cancer Cells., PMID:38942031
For research use only. Not for human or drug use.
