Catalog No.
YHJ33301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala627-Glu802
Predicted molecular weight
22.68 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92796
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
SAP102, Synapse-associated protein 102, Neuroendocrine-DLG, KIAA1232, DLG3, SAP-102, XLMR, Disks large homolog 3
Multifaceted roles of DLG3/SAP102 in neurophysiology, neurological disorders and tumorigenesis., PMID:39638232
Investigation and validation of neurotransmitter receptor-related biomarkers for forecasting clinical outcomes and immunotherapeutic efficacy in breast cancer., PMID:39615806
Interplay of miRNAs and molecular pathways in spaceflight-induced depression: Insights from a rat model using simulated complex space environment., PMID:39037540
Distinct SAP102 and PSD-95 Nano-organization Defines Multiple Types of Synaptic Scaffold Protein Domains at Single Synapses., PMID:38777601
SOX4 regulates proliferation and apoptosis of human ovarian granulosa-like tumor cell line KGN through the Hippo pathway., PMID:38447391
Identification of a DLG3 stop mutation in the MRX20 family., PMID:38273165
DLG3 variants caused X-linked epilepsy with/without neurodevelopmental disorders and the genotype-phenotype correlation., PMID:38249294
Hippocampal proteomic changes in high-fat diet-induced obese mice associated with memory decline., PMID:38142716
A liaison between chaperone-mediated autophagy and exocytotic lysosomes controls the dendritic metastable proteome., PMID:37876225
Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal., PMID:37590146
Identification of prognostic biomarkers of breast cancer based on the immune-related gene module., PMID:37584152
The Hippo signaling pathway contributes to the 2,5-Hexadion-induced apoptosis of ovarian granulosa cells., PMID:37563629
COP1 facilitates the proliferation, invasion, and migration of glioma cells by ubiquitination of DLG3 protein., PMID:37356109
Proteomics and weighted gene correlated network analysis reveal glutamatergic synapse signaling in diazepam treatment of alcohol withdrawal., PMID:36712652
Differential Expression of the Genes Coding for Adipokines and Epithelial Cell Polarity Components in Women With Low and High Mammographic Density., PMID:35725805
Hypermethylation of DLG3 Promoter Upregulates RAC1 and Activates the PI3K/AKT Signaling Pathway to Promote Breast Cancer Progression., PMID:34765009
Diagnostic yield of whole-exome sequencing in non-syndromic intellectual disability., PMID:33739554
RT-PCR analysis of mRNA revealed the splice-altering effect of rare intronic variants in monogenic disorders., PMID:32776513
Silence of lncRNA MIAT-mediated inhibition of DLG3 promoter methylation suppresses breast cancer progression via the Hippo signaling pathway., PMID:32593652
Immune-related genes in tumor-specific CD4+ and CD8+ T cells in colon cancer., PMID:32571262
KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity., PMID:32430335
Phospho-proteomic discovery of novel signal transducers including thioredoxin-interacting protein as mediators of erythropoietin-dependent human erythropoiesis., PMID:32259549
Triple diagnosis of Wiedemann-Steiner, Waardenburg and DLG3-related intellectual disability association found by WES: A case report., PMID:32246869
A Novel DLG3 Mutation Expanding the Phenotype of X-Linked Intellectual Disability Caused by DLG3 Nonsense Variants., PMID:32021600
SAP102 contributes to hyperalgesia formation in the cancer induced bone pain rat model by anchoring NMDA receptors., PMID:31682872
Profile of cortical N-methyl-D-aspartate receptor subunit expression associates with inherent motor impulsivity in rats., PMID:31295463
High expression of DLG3 is associated with decreased survival from breast cancer., PMID:31271664
Challenges in the clinical interpretation of small de novo copy number variants in neurodevelopmental disorders., PMID:31085274
[Chronic phosphoproteomic in temporal lobe epilepsy mouse models induced by kainic acid]., PMID:30996354
L-DOPA-Induced Motor Impairment and Overexpression of Corticostriatal Synaptic Components Are Improved by the mGluR5 Antagonist MPEP in 6-OHDA-Lesioned Rats., PMID:30439288
A single cocaine administration alters dendritic spine morphology and impairs glutamate receptor synaptic retention in the medial prefrontal cortex of adolescent rats., PMID:30092246
SAP102 regulates synaptic AMPAR function through a CNIH-2-dependent mechanism., PMID:30067114
Dynamic SAP102 expression in the hippocampal subregions of rats and APP/PS1 mice of various ages., PMID:29574717
Regulation of SAP102 Synaptic Targeting by Phosphorylation., PMID:29282697
Skewed X-inactivation in a family with DLG3-associated X-linked intellectual disability., PMID:28777483
Protracted and asynchronous accumulation of PSD95-family MAGUKs during maturation of nascent dendritic spines., PMID:28388013
Quantitative Tyrosine Phosphoproteomics of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor-treated Lung Adenocarcinoma Cells Reveals Potential Novel Biomarkers of Therapeutic Response., PMID:28331001
Membrane-associated guanylate kinase scaffolds organize a horizontal cell synaptic complex restricted to invaginating contacts with photoreceptors., PMID:27558197
Development of Novel miRNA-based Vaccines and Antivirals against Enterovirus 71., PMID:27510488
Altered thalamocortical development in the SAP102 knockout model of intellectual disability., PMID:27466188
A non-coding variant in the 5' UTR of DLG3 attenuates protein translation to cause non-syndromic intellectual disability., PMID:27222290
Liver X Receptor Agonist Modifies the DNA Methylation Profile of Synapse and Neurogenesis-Related Genes in the Triple Transgenic Mouse Model of Alzheimer's Disease., PMID:26553261
Synaptic Consolidation Normalizes AMPAR Quantal Size following MAGUK Loss., PMID:26247861
Neurobeachin Regulates Glutamate- and GABA-Receptor Targeting to Synapses via Distinct Pathways., PMID:25934101
Adolescent intermittent alcohol exposure: persistence of structural and functional hippocampal abnormalities into adulthood., PMID:25916839
Dynamic regulation of a cell adhesion protein complex including CADM1 by combinatorial analysis of FRAP with exponential curve-fitting., PMID:25780926
Targeting protein-protein interactions with trimeric ligands: high affinity inhibitors of the MAGUK protein family., PMID:25658767
Subunit-specific regulation of N-methyl-D-aspartate (NMDA) receptor trafficking by SAP102 protein splice variants., PMID:25555912
Selective synaptic targeting of the excitatory and inhibitory presynaptic organizers FGF22 and FGF7., PMID:25431136
Flattop regulates basal body docking and positioning in mono- and multiciliated cells., PMID:25296022
For research use only. Not for human or drug use.
