Catalog No.
YHJ32401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp251
Predicted molecular weight
31.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92688
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
APRIL, Acidic leucine-rich nuclear phosphoprotein 32 family member B, PHAPI2, Silver-stainable protein SSP29, Acidic protein rich in leucines, ANP32B, Putative HLA-DR-associated protein I-2
ANP32 proteins from ticks and vertebrates are key host factors for replication of Bourbon virus across species., PMID:40366164
Evolutionary Pro-To-Thr Mutation in the Intrinsically Disordered Domain of ANP32 Family Members Modulates Their Target Binding Modes., PMID:39887951
Human ANP32A/B are SUMOylated and utilized by avian influenza virus NS2 protein to overcome species-specific restriction., PMID:39737943
Anp32b Deficiency Suppresses Ocular Development by Repression of Pax6., PMID:39504945
Equine ANP32 proteins support influenza A virus RNA polymerase activity., PMID:39491182
Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase., PMID:39160148
Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation., PMID:38750014
PB2 residue 473 contributes to the mammalian virulence of H7N9 avian influenza virus by modulating viral polymerase activity via ANP32A., PMID:38421166
Acidic Leucine-Rich Nuclear Protein Phosphatase 32B Promotes Prostate Adenocarcinoma Cell Progression by Regulating Apoptosis and Epithelial-Mesenchymal Transition., PMID:38401083
Super enhancer related gene ANP32B promotes the proliferation of acute myeloid leukemia by enhancing MYC through histone acetylation., PMID:38383388
Hepatitis B virus RNAs co-opt ELAVL1 for stabilization and CRM1-dependent nuclear export., PMID:38306394
ANP32B inhibition suppresses the growth of prostate cancer cells by regulating c-Myc signaling., PMID:38266312
N-acetyltransferase NAT10 controls cell fates via connecting mRNA cytidine acetylation to chromatin signaling., PMID:38215194
The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A., PMID:37858472
An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerization., PMID:37816726
Creating resistance to avian influenza infection through genome editing of the ANP32 gene family., PMID:37816720
ANP32B suppresses B-cell acute lymphoblastic leukemia through activation of PU.1 in mice., PMID:37137487
Mammalian ANP32A and ANP32B Proteins Drive Differential Polymerase Adaptations in Avian Influenza Virus., PMID:37074204
Avian Influenza A Virus Polymerase Can Utilize Human ANP32 Proteins To Support cRNA but Not vRNA Synthesis., PMID:36645303
ANP32B promotes lung cancer progression by regulating VDAC1., PMID:36642319
BRD4 PROTAC degrader MZ1 exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B genes., PMID:36170346
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ., PMID:35891793
Enhanced Type I Collagen Synthesis in Fibroblasts by Dermal Stem/Progenitor Cell-Derived Exosomes., PMID:35786595
ANP32 Family as Diagnostic, Prognostic, and Therapeutic Biomarker Related to Immune Infiltrates in Hepatocellular Carcinoma., PMID:35280441
KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity., PMID:35044222
Epigenetic and Immune-Cell Infiltration Changes in the Tumor Microenvironment in Hepatocellular Carcinoma., PMID:34925377
A natural variant in ANP32B impairs influenza virus replication in human cells., PMID:34524075
ANP32B-mediated repression of p53 contributes to maintenance of normal and CML stem cells., PMID:34359074
Gene network and biological pathways associated with susceptibility to differentiated thyroid carcinoma., PMID:33903625
Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c., PMID:33882408
The mammalian Hedgehog pathway is modulated by ANP32 proteins., PMID:33761414
Enrichment of Neurodegenerative Microglia Signature in Brain-Derived Extracellular Vesicles Isolated from Alzheimer's Disease Mouse Models., PMID:33534581
Selective usage of ANP32 proteins by influenza B virus polymerase: Implications in determination of host range., PMID:33045004
Swine ANP32A Supports Avian Influenza Virus Polymerase., PMID:32269123
ANP32B Deficiency Protects Mice From Lethal Influenza A Virus Challenge by Dampening the Host Immune Response., PMID:32231671
A unique feature of swine ANP32A provides susceptibility to avian influenza virus infection in pigs., PMID:32084248
Interaction of host cellular factor ANP32B with matrix proteins of different paramyxoviruses., PMID:31793855
Host-Specific Restriction of Avian Influenza Virus Caused by Differential Dynamics of ANP32 Family Members., PMID:31581291
ANP32A and ANP32B are key factors in the Rev-dependent CRM1 pathway for nuclear export of HIV-1 unspliced mRNA., PMID:31444273
ANP32 Proteins Are Essential for Influenza Virus Replication in Human Cells., PMID:31217244
ANP32B, or not to be, that is the question for influenza virus., PMID:31179971
Species specific differences in use of ANP32 proteins by influenza A virus., PMID:31159925
Fundamental Contribution and Host Range Determination of ANP32A and ANP32B in Influenza A Virus Polymerase Activity., PMID:30996088
The acidic protein rich in leucines Anp32b is an immunomodulator of inflammation in mice., PMID:30890743
Label-free tissue proteomics can classify oral squamous cell carcinoma from healthy tissue in a stage-specific manner., PMID:30409303
Prothymosin α interacts with SET, ANP32A and ANP32B and other cytoplasmic and mitochondrial proteins in proliferating cells., PMID:29106904
Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinoma., PMID:28486557
Identification of serum protein biomarkers for utrophin based DMD therapy., PMID:28252048
Targeted Proteomics for Multiplexed Verification of Markers of Colorectal Tumorigenesis., PMID:28062797
ANP32B deficiency impairs proliferation and suppresses tumor progression by regulating AKT phosphorylation., PMID:26844697
For research use only. Not for human or drug use.
