Catalog No.
YHJ32301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala67
Predicted molecular weight
9.06 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92686
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RC3, Neurogranin, Ng, NRGN
Note
For research use only.
Extracellular vesicles in patients in the acute phase of psychosis and after clinical improvement: an explorative study., PMID:32995075
Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome., PMID:33032807
Molecular forms of neurogranin in cerebrospinal fluid., PMID:33249594
Decreased nesting behavior, selective increases in locomotor activity in a novel environment, and paradoxically increased open arm exploration in Neurogranin knockout mice., PMID:33270377
Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer's disease., PMID:33279949
Serial plasma biomarkers of brain injury in infants with neonatal encephalopathy treated with therapeutic hypothermia., PMID:33654280
Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus., PMID:33720890
Association of neurogranin gene expression with Alzheimer's disease pathology in the perirhinal cortex., PMID:33860070
Proteomic discovery in sickle cell disease: Elevated neurogranin levels in children with sickle cell disease., PMID:33915030
Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients., PMID:33924468
Comparative description of the mRNA expression profile of Na+ /K+ -ATPase isoforms in adult mouse nervous system., PMID:34415061
Cerebrospinal fluid markers for synaptic function and Alzheimer type changes in late life depression., PMID:34645914
Generation and Release of Neurogranin, Vimentin, and MBP Proteolytic Peptides, Following Traumatic Brain Injury., PMID:34762230
Serum brain injury biomarkers are gestationally and post-natally regulated in non-brain injured neonates., PMID:34923579
A new biomarker in the differential diagnosis of epileptic seizure: Neurogranin., PMID:35152125
Multiple Sclerosis Biomarker Candidates Revealed by Cell-Type-Specific Interactome Analysis., PMID:35483054
A new generation of AD biomarkers: 2019 to 2021., PMID:35636691
Low androgen level impairs erectile function of rat by regulating the Ng/CaN/AKT/eNOS pathway in penile corpus cavernosum., PMID:35678097
P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles., PMID:35841015
Neurogranin inhibits calcineurin in murine soleus muscle: Effects of heterozygous knockdown on muscle adaptations to tenotomy and fatigue resistance., PMID:35878428
Neurogranin-like immunoreactivity in the zebrafish brain during development., PMID:36018391
The effects of neurogranin knockdown on SERCA pump efficiency in soleus muscles of female mice fed a high fat diet., PMID:36072929
Early life stressful experiences escalate aggressive behavior in adulthood via changes in transthyretin expression and function., PMID:36226913
Persistent Depletion of Neuroprotective Factors Accompanies Neuroinflammatory, Neurodegenerative, and Vascular Remodeling Spectra in Serum Three Months after Non-Emergent Cardiac Surgery., PMID:36289630
Sex, Age, and Regional Differences in CHRM1 and CHRM3 Genes Expression Levels in the Human Brain Biopsies: Potential Targets for Alzheimer's Disease-related Sleep Disturbances., PMID:36475335
Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer's disease: novel methodology and clinical proof of concept., PMID:37842184
Molecular Characterization of Neurogranin (NRGN) Gene from Red‑Bellied Pacu (Piaractus brachypomus)., PMID:37922064
Suppression of neurogranin expression by disruption of epigenetic DNA methylation in hippocampal mature granule cells after developmental exposure to neurotoxicants in rats., PMID:37926403
Neuroinflammation driven by Human Immunodeficiency Virus-1 (HIV-1) directs the expression of long noncoding RNA RP11-677M14.2 resulting in dysregulation of Neurogranin in vivo and in vitro., PMID:38260270
CSF protein ratios with enhanced potential to reflect Alzheimer's disease pathology and neurodegeneration., PMID:38350954
Temporal-Specific Sex and Injury-Dependent Changes on Neurogranin-Associated Synaptic Signaling After Controlled Cortical Impact in Rats., PMID:38376763
Comprehensive analysis of DNA methylation gene expression profiles in GEO dataset reveals biomarkers related to malignant transformation of sinonasal inverted papilloma., PMID:38427106
Evaluation of neurogranin levels in a rat model of diffuse axonal injury., PMID:38587321
Probing molecular pathways: Illuminating the connection between COVID-19 and Alzheimer's disease through the endocannabinoid system dynamics., PMID:38619024
Neuroinflammation driven by human immunodeficiency virus-1 (HIV-1) directs the expression of long noncoding RNA RP11-677M14.2 resulting in dysregulation of neurogranin in vivo and in vitro., PMID:38659061
Alterations of human CSF and serum-based mitophagy biomarkers in the continuum of Alzheimer disease., PMID:38695174
Mitochondrial dysfunction is associated with cognitive impairment in adults with OSA without dementia., PMID:38704871
Benchmarking of a multi-biomarker low-volume panel for Alzheimer's Disease and related dementia research., PMID:38947090
A genetic and proteomic comparison of key AD biomarkers across tissues., PMID:39077866
CSF neurogranin levels as a biomarker in Alzheimer's disease and frontotemporal lobar degeneration: a cross-sectional analysis., PMID:39242539
Different Proteins as Biomarkers for Sac Shrinkage After Endovascular Aortic Repair of Abdominal Aortic Aneurysms., PMID:39590217
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds., PMID:39668376
Selenium promotes neural development through the regulation of GPX4 and SEPP1 in an iPSC-derived neuronal model., PMID:39708777
Inflammatory Response of THP1 and U937 Cells: The RNAseq Approach., PMID:39768153
Novel plasma biomarkers of amyloid plaque pathology and cortical thickness: Evaluation of the NULISA targeted proteomic platform in an ethnically diverse cohort., PMID:39989429
Elevated serum and cerebrospinal fluid levels of the synaptophysin and neurogranin with its altered brain expression in the early phase of traumatic brain injury as a potential marker of synaptic injury., PMID:40146393
New molecular markers to differentiate carbon dioxide intoxication from asphyxia due to oxygen deficiency., PMID:40167862
Molecular Biomarkers of Neurodegeneration in Amyotrophic Lateral Sclerosis., PMID:40254405
Elucidating SARS-CoV-2 neurotropism: a comprehensive Mendelian randomization study on cerebrospinal fluid biomarkers and their relevance to COVID-19 neurological manifestations., PMID:40296111
Neurogranin facilitates maintaining the immunosuppressive state of hepatocellular carcinoma by promoting TGF-β1 secretion., PMID:40316076
For research use only. Not for human or drug use.
