Catalog No.
YHJ29901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn25-Arg167
Predicted molecular weight
19.62 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8WW32
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HMGB4, High mobility group protein B4
Note
For research use only.
Protein kinase CK2 differentially phosphorylates maize chromosomal high mobility group B (HMGB) proteins modulating their stability and DNA interactions., PMID:11694523
Phosphorylation of maize and Arabidopsis HMGB proteins by protein kinase CK2alpha., PMID:12653554
Ectopic expression of the maize chromosomal HMGB1 protein causes defects in root development of tobacco seedlings., PMID:15110790
Interactions of the basic N-terminal and the acidic C-terminal domains of the maize chromosomal HMGB1 protein., PMID:15209498
Characterization of transgenic Arabidopsis plants overexpressing high mobility group B proteins under high salinity, drought or cold stress., PMID:17169924
HMGB4, a novel member of the HMGB family, is preferentially expressed in the mouse testis and localizes to the basal pole of elongating spermatids., PMID:18987332
HMGB proteins: interactions with DNA and chromatin., PMID:20123072
Nucleocytoplasmic distribution of the Arabidopsis chromatin-associated HMGB2/3 and HMGB4 proteins., PMID:20940346
High-mobility group boxes mediate cell proliferation and radiosensitivity via retinoblastoma-interaction-dependent and -independent mechanisms., PMID:22655796
Binding interaction of HMGB4 with cisplatin-modified DNA., PMID:22901013
Cryopreserved bovine spermatozoal transcript profile as revealed by high-throughput ribonucleic acid sequencing., PMID:23303677
Combining RNA and protein profiling data with network interactions identifies genes associated with spermatogenesis in mouse and human., PMID:25609838
HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation., PMID:27608812
Repair shielding of platinum-DNA lesions in testicular germ cell tumors by high-mobility group box protein 4 imparts cisplatin hypersensitivity., PMID:28096358
[Clinical application of high mobility group box nuclear protein 1 subcomponent in the progression of liver cancer]., PMID:30616326
RNA-Seq analysis reveals functionally relevant coding and non-coding RNAs in crossbred bull spermatozoa., PMID:33069132
The role of high mobility group protein B3 (HMGB3) in tumor proliferation and drug resistance., PMID:33428061
Omics and Male Infertility: Highlighting the Application of Transcriptomic Data., PMID:35207567
HMGB3 inhibition by miR-142-3p/sh-RNA modulates autophagy and induces apoptosis via ROS accumulation and mitochondrial dysfunction and reduces the tumorigenic potential of human breast cancer cells., PMID:35753437
An integrative analysis of DNA methylation and gene expression to predict lung adenocarcinoma prognosis., PMID:36105089
Transcriptome analyses in infertile men reveal germ cell-specific expression and splicing patterns., PMID:36446526
Comparative proteomics and phosphoproteomics analysis reveals differential sperm motility in Mediterranean buffalo semen., PMID:39961484
For research use only. Not for human or drug use.
