Catalog No.
YHJ29801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile107-Phe400
Predicted molecular weight
34.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8WVQ1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CANT1, Putative NF-kappa-B-activating protein 107, Apyrase homolog, Soluble calcium-activated nucleotidase 1, SCAN-1, SHAPY, Putative MAPK-activating protein PM09
Recognizing multiple epiphyseal dysplasia in children presenting with joint pain: a commonly overlooked skeletal dysplasia., PMID:40392407
Prediction of potential targets of aloe-emodin in the treatment of hepatocellular carcinoma using network pharmacology combined with bioinformatics., PMID:40186059
CANT1 Is Involved in Collagen Fibrogenesis in Tendons by Regulating the Synthesis of Dermatan/Chondroitin Sulfate Attached to the Decorin Core Protein., PMID:40141107
Cant1 Affects Cartilage Proteoglycan Properties: Aggrecan and Decorin Characterization in a Mouse Model of Desbuquois Dysplasia Type 1., PMID:39334831
Clinical and Genetic Insights into Desbuquois Dysplasia: Review of 111 Case Reports., PMID:39273648
WTAP-mediated N6-methyladenine Modification of circEEF2 Promotes Lung Adenocarcinoma Tumorigenesis by Stabilizing CANT1 in an IGF2BP2-dependent Manner., PMID:38619801
Pan-cancer analysis predicts CANT1 as a potential prognostic, immunologic biomarker., PMID:38369265
Proteome profiling identifies circulating biomarkers associated with hepatic steatosis in subjects with Prader-Willi syndrome., PMID:38034016
Upregulated CANT1 is correlated with poor prognosis in hepatocellular carcinoma., PMID:37858061
Circ_0001715 accelerated lung adenocarcinoma process by the miR-1322/CANT1 axis., PMID:37553672
Integrated proteomics and metabolomics analysis of lumbar in a rat model of osteoporosis treated with Gushukang capsules., PMID:36522793
A circular network of purine metabolism as coregulators of dilated cardiomyopathy., PMID:36401332
Prenatal Cases Reflect the Complexity of the COL1A1/2 Associated Osteogenesis Imperfecta., PMID:36140746
Identification of fusions with potential clinical significance in melanoma., PMID:35871080
Evaluation of cfDNA as an early detection assay for dense tissue breast cancer., PMID:35589867
CANT1 serves as a potential prognostic factor for lung adenocarcinoma and promotes cell proliferation and invasion in vitro., PMID:35090419
Calcium-activated nucleotides 1 (CANT1)-driven nuclear factor-k-gene binding (NF-ĸB) signaling pathway facilitates the lung cancer progression., PMID:35068336
Phenotypic Characterization of Immortalized Chondrocytes from a Desbuquois Dysplasia Type 1 Mouse Model: A Tool for Studying Defects in Glycosaminoglycan Biosynthesis., PMID:34502207
A Reductionist Approach Using Primary and Metastatic Cell-Derived Extracellular Vesicles Reveals Hub Proteins Associated with Oral Cancer Prognosis., PMID:34186243
The effect and mechanism of miR-607/CANT1 axis in lung squamous carcinoma., PMID:33675611
Cloning, expression and enzyme activity delineation of two novel CANT1 mutations: the disappearance of dimerization may indicate the change of protein conformation and even function., PMID:32907608
Prognosis and personalized treatment prediction in TP53-mutant hepatocellular carcinoma: an in silico strategy towards precision oncology., PMID:32789496
LncRNA CANT1 suppresses retinoblastoma progression by repellinghistone methyltransferase in PI3Kγ promoter., PMID:32366932
CANT1 deficiency in a mouse model of Desbuquois dysplasia impairs glycosaminoglycan synthesis and chondrocyte differentiation in growth plate cartilage., PMID:32277574
Pseudodiastrophic dysplasia expands the known phenotypic spectrum of defects in proteoglycan biosynthesis., PMID:31988067
Re-analysis of whole-exome sequencing data uncovers novel diagnostic variants and improves molecular diagnostic yields for sudden death and idiopathic diseases., PMID:31847883
[Analysis of CANT1 gene variant in a girl with Desbuquois dysplasia type I]., PMID:31813149
A novel homozygous variant in CANT1 in a patient with Kim-type Desbuquois dysplasia., PMID:31348018
Calcium-activated nucleotidase 1 silencing inhibits proliferation, migration, and invasion in human clear cell renal cell carcinoma., PMID:31102300
A novel gene (FAM20B encoding glycosaminoglycan xylosylkinase) for neonatal short limb dysplasia resembling Desbuquois dysplasia., PMID:30847897
Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification., PMID:30439444
UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis., PMID:29898404
Nonsyndromic cerebellar ataxias associated with disorders of DNA single-strand break repair., PMID:29891053
MED resulting from recessively inherited mutations in the gene encoding calcium-activated nucleotidase CANT1., PMID:28742282
Endoplasmic reticulum retention of xylosyltransferase 1 (XYLT1) mutants underlying Desbuquois dysplasia type II., PMID:28462984
CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma., PMID:28330694
Novel and recurrent XYLT1 mutations in two Turkish families with Desbuquois dysplasia, type 2., PMID:27881841
[Medicinal-powder-separated Long-snake Moxibustion over the Governor Vessel with Different Skin Vesiculation Conditions for Treatment of Patients with Rheumatoid Arthritis]., PMID:29071928
Desbuquois dysplasia type II in a patient with a homozygous mutation in XYLT1 and new unusual findings., PMID:27481334
Hypermutation of DPYD Deregulates Pyrimidine Metabolism and Promotes Malignant Progression., PMID:26609109
A novel CANT1 mutation in three Indian patients with Desbuquois dysplasia Kim type., PMID:25486376
XYLT1 mutations in Desbuquois dysplasia type 2., PMID:24581741
Further delineation of CANT1 phenotypic spectrum and demonstration of its role in proteoglycan synthesis., PMID:22539336
Ca2+-activated nucleotidase 1, a novel target gene for the transcriptional repressor DREAM (downstream regulatory element antagonist modulator), is involved in protein folding and degradation., PMID:22451650
Desbuquois dysplasia type I and fetal hydrops due to novel mutations in the CANT1 gene., PMID:21654728
The androgen-regulated Calcium-Activated Nucleotidase 1 (CANT1) is commonly overexpressed in prostate cancer and is tumor-biologically relevant in vitro., PMID:21435463
A founder mutation of CANT1 common in Korean and Japanese Desbuquois dysplasia., PMID:21412251
CANT1 mutation is also responsible for Desbuquois dysplasia, type 2 and Kim variant., PMID:21037275
Mutation of CANT1 causes Desbuquois dysplasia., PMID:20425819
A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer., PMID:18794152
For research use only. Not for human or drug use.
