Catalog No.
YHJ29201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser482-Ser903
Predicted molecular weight
47.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8WUI4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HDAC7A, HD7, HD7a, Histone deacetylase 7, HDAC7, Histone deacetylase 7A
HDAC7 influences ER-⍺ transcription via NCoR-HDAC3 dissociation., PMID:40513928
HDAC7 promotes renal cancer progression by reprogramming branched-chain amino acid metabolism., PMID:40465706
Activation of SIK1 by phanginin A regulates skeletal muscle glucose uptake by phosphorylating HADC4/5/7 and enhancing GLUT4 expression and translocation., PMID:40192973
Bioinformatics analysis of electroacupuncture treatment for ischemic stroke: exploring transcriptional regulatory mechanisms mediated by super-enhancers., PMID:40109665
DNMT3a promotes LUAD cell proliferation and metastasis by activating the HDAC7 signalling pathway., PMID:39990668
Scaffolding Activities of Pseudodeacetylase HDAC7., PMID:39908122
Modified Xiao-Qing-Long-decoction prevents inflammation and promotes Nur77 expression in mice with acute respiratory distress syndrome by inhibiting HDAC7 expression., PMID:39902793
Nuclear to Cytoplasmic Transport Is a Druggable Dependency in HDAC7-driven Small Cell Lung Cancer., PMID:39887933
Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis., PMID:39806423
In vitro and in silico insights into antimicrobial and anticancer activities of novel imidazo[2,1-b][1,3,4]thiadiazoles., PMID:39738776
Toxin protein LukS-PV targeting complement receptor C5aR1 inhibits cell proliferation in hepatocellular carcinoma via the HDAC7-Wnt/β-catenin axis., PMID:39736396
Characterization of molecular interactions between HDAC7 and MEF2A., PMID:39660765
HDAC7 drives glioblastoma to a mesenchymal-like state via LGALS3-mediated crosstalk between cancer cells and macrophages., PMID:39629136
Interplay between acetylation and ubiquitination controls PSAT1 protein stability in lung adenocarcinoma., PMID:39433916
HDAC7 promotes ovarian cancer malignancy via AKT/mTOR signalling pathway., PMID:39431349
HDAC7 promotes cardiomyocyte proliferation by suppressing myocyte enhancer factor 2., PMID:39394661
Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain., PMID:39373581
Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia., PMID:39362994
Therapeutic role of histone deacetylase inhibition in an in vitro model of Graves' orbitopathy., PMID:39329199
Synthesis and biological evaluation of ortho-phenyl phenylhydroxamic acids containing phenothiazine with improved selectivity for class IIa histone deacetylases., PMID:39316378
Melatonin Attenuates Diabetic Retinopathy by Regulating EndMT of Retinal Vascular Endothelial Cells via Inhibiting the HDAC7/FOXO1/ZEB1 Axis., PMID:39300782
HDAC7 is a potential therapeutic target in acute erythroid leukemia., PMID:39277669
Histone deacetylase expression following cisplatin-induced acute kidney injury in male and female mice., PMID:39116350
The Epigenetic Modifiers HDAC2 and HDAC7 Inversely Associate with Cancer Stemness and Immunity in Solid Tumors., PMID:39063083
PROTAC-Mediated HDAC7 Protein Degradation Unveils Its Deacetylase-Independent Proinflammatory Function in Macrophages., PMID:39049738
Differential Gene Expression Involved in Bone Turnover of Mice Expressing Constitutively Active TGFβ Receptor Type I., PMID:38892016
Epigenetics., PMID:38884720
Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation., PMID:38657041
Proteomic analysis of the serum in dogs with pulmonary hypertension secondary to myxomatous mitral valve disease: the preliminary study., PMID:38596466
Mesenchymal Stem Cell-Derived Extracellular Vesicles Alleviate Brain Damage Following Subarachnoid Hemorrhage via the Interaction of miR-140-5p and HDAC7., PMID:38592585
Folding of Class IIa HDAC Derived Peptides into α-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA., PMID:38492719
Epigenetic regulators controlling osteogenic lineage commitment and bone formation., PMID:38341164
Construction of a molecular inflammatory predictive model with histone modification-related genes and identification of CAMK2D as a potential response signature to infliximab in ulcerative colitis., PMID:38274809
AMPK-mediated CD47 H3K4 methylation promotes phagocytosis evasion of glioma stem cells post-radiotherapy., PMID:38218171
Bioinformatic identification and experiment validation reveal 6 hub genes, promising diagnostic and therapeutic targets for Alzheimer's disease., PMID:38167011
Epigenetic and Metabolic Reprogramming of Fibroblasts in Crohn's Disease Strictures Reveals Histone Deacetylases as Therapeutic Targets., PMID:38069679
Unveiling Circular RNA-Mediated Regulatory Mechanisms in Necroptosis in Premature Ovarian Failure., PMID:38062819
Comprehensive analysis of HDAC7 expression and its prognostic value in diffuse large B cell lymphoma: A review., PMID:37960766
SIKs Regulate HDAC7 Stabilization and Cytokine Recall in Late-Stage T Cell Effector Differentiation., PMID:37947442
PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity., PMID:37878054
Epigenetic regulation exerted by Caliphruria subedentata and galantamine: an in vitro and in silico approach for mimic Alzheimer's disease., PMID:37814967
Deacetylation of FOXP1 by HDAC7 potentiates self-renewal of mesenchymal stem cells., PMID:37507770
Tropolones and Thailandepsin B as Lead-like Natural Compounds in the Development of Potent and Selective Histone Deacetylase Inhibitors., PMID:37424350
Identification of bicalutamide resistance-related genes and prognosis prediction in patients with prostate cancer., PMID:37143720
Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas., PMID:37041276
LncRNA HOXB-AS4 promotes proliferation and migration of colorectal cancer via the miR-140-5p/hdac7 axis., PMID:36951606
Alternative splicing of HDAC7 regulates its interaction with 14-3-3 proteins to alter histone marks and target gene expression., PMID:36933216
Ellagitannin Punicalagin Disrupts the Pathways Related to Bacterial Growth and Affects Multiple Pattern Recognition Receptor Signaling by Acting as a Selective Histone Deacetylase Inhibitor., PMID:36917202
Rare and low-frequency coding genetic variants contribute to pediatric-onset multiple sclerosis., PMID:36755464
Cell-of-Origin Targeted Drug Repurposing for Triple-Negative and Inflammatory Breast Carcinoma with HDAC and HSP90 Inhibitors Combined with Niclosamide., PMID:36672285
For research use only. Not for human or drug use.
