Catalog No.
YHJ26001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile242-Met384
Predicted molecular weight
18.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8NFU0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Bestrophin-4, BEST4, VMD2L2, Vitelliform macular dystrophy 2-like protein 2
Interferon-responsive intestinal BEST4/CA7+ cells are targets of bacterial diarrheal toxins., PMID:40010349
CFTR High Expresser BEST4+ cells are pH-sensing neuropod cells: new implications for intestinal physiology and Cystic Fibrosis disease., PMID:39974899
Bestrophin-4 relays HES4 and interacts with TWIST1 to suppress epithelial-to-mesenchymal transition in colorectal cancer cells., PMID:39699952
Single-cell resolution of intestinal regeneration in pythons without crypts illuminates conserved vertebrate regenerative mechanisms., PMID:39423244
BEST4+ cells in the intestinal epithelium., PMID:38557358
Single-cell resolution of the adult zebrafish intestine under conventional conditions and in response to an acute Vibrio cholerae infection., PMID:37948182
Mechanistic insights into zearalenone-accelerated colorectal cancer in mice using integrative multi-omics approaches., PMID:36915382
Cytosolic domain regulates the calcium sensitivity and surface expression of BEST1 channels in the HEK293 cells., PMID:36593105
Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq., PMID:36300623
OTOP2, Inversely Modulated by miR-3148, Inhibits CRC Cell Migration, Proliferation and Epithelial-Mesenchymal Transition: Evidence from Bioinformatics Data Mining and Experimental Verification., PMID:35418782
Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq., PMID:35350199
Uncovering potential genes in colorectal cancer based on integrated and DNA methylation analysis in the gene expression omnibus database., PMID:35114976
Oncogenic potential of BEST4 in colorectal cancer via activation of PI3K/Akt signaling., PMID:35058597
Cells of the human intestinal tract mapped across space and time., PMID:34497389
Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution., PMID:33691112
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis., PMID:31348891
Expression and Purification of Mammalian Bestrophin Ion Channels., PMID:30124653
Swelling-activated Cl- currents and intracellular CLC-3 are involved in proliferation of human pulmonary artery smooth muscle cells., PMID:24284495
Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells., PMID:24223998
Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1., PMID:19237432
Functional assembly and purinergic activation of bestrophins., PMID:19130075
Bestrophin Cl- channels are highly permeable to HCO3-., PMID:18400985
Small-conductance Cl- channels contribute to volume regulation and phagocytosis in microglia., PMID:17927776
Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family., PMID:12032738
For research use only. Not for human or drug use.
