Catalog No.
YHJ21501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala97-Ala300
Predicted molecular weight
48.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8N3V7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA1029, SYNPO, Synaptopodin
Benzo[b]fluoranthene is involved in idiopathic membranous nephropathy by inducing podocyte injury., PMID:40443401
Trametinib ameliorated Adriamycin-induced podocyte injury by inhibiting METTL3 modified m6A RCAN1 RNA methylation., PMID:40287046
Umbilical Cord Mesenchymal Stem Cells Attenuate Podocyte Injury in Diabetic Nephropathy Rats by Inhibiting Angpltl4/Integrin β3 in the Glomerulus., PMID:40256245
Prenatal Alcohol Exposure Inhibits Transient Expression of Autophagy and Synaptic Proteins in Developing Brain., PMID:40084086
Integration of metabolomics and transcriptomics reveals the mechanism of TMEM30A downregulation induced FSGS podocyte injury., PMID:39907744
The Immunosuppressive Drug LF15-0195 Acts Also on Glomerular Lesions, by a Change in Cytoskeleton Distribution in Podocyte., PMID:39074452
Association of the podocyte phenotype with extracapillary hypercellularity in patients with diabetic kidney disease., PMID:39066994
Cyclosporine A Protects Podocytes by Regulating Transgelin in Adriamycin-Induced Podocyte Injury., PMID:38952124
Deletion of IRE1α in podocytes exacerbates diabetic nephropathy in mice., PMID:38778209
A simple protocol to establish a conditionally immortalized mouse podocyte cell line., PMID:38773220
Indoxyl Sulfate Aggravates Podocyte Damage through the TGF-β1/Smad/ROS Signalling Pathway., PMID:38735279
Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy., PMID:38628140
Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses., PMID:38566234
Synaptopodin Regulates Denervation-Induced Plasticity at Hippocampal Mossy Fiber Synapses., PMID:38247806
Autism-related KLHL17 and SYNPO act in concert to control activity-dependent dendritic spine enlargement and the spine apparatus., PMID:37651441
Bioinformatics Analysis of Next Generation Sequencing Data Identifies Molecular Biomarkers Associated With Type 2 Diabetes Mellitus., PMID:36844983
Derivation of the Immortalized Cell Line UM51-PrePodo-hTERT and Its Responsiveness to Angiotensin II and Activation of the RAAS Pathway., PMID:36766685
The chaperone-assisted selective autophagy complex dynamics and dysfunctions., PMID:36594740
Integrated Bioinformatics and Clinical Correlation Analysis of Key Genes, Pathways, and Potential Therapeutic Agents Related to Diabetic Nephropathy., PMID:35637650
Activation of the Renin-Angiotensin System Disrupts the Cytoskeletal Architecture of Human Urine-Derived Podocytes., PMID:35406662
Effects of SGLT2 inhibitors on patients with diabetic kidney disease: A preliminary study on the basis of podocyturia., PMID:35229458
Atractylodin inhibits fructose-induced human podocyte hypermotility via anti-oxidant to down-regulate TRPC6/p-CaMK4 signaling., PMID:34780752
Consensus gene modules related to levels of bone mineral density (BMD) among smokers and nonsmokers., PMID:34743649
All-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells., PMID:34723795
Increasing urinary podocyte mRNA excretion and progressive podocyte loss in kidney contribute to the high risk of long-term renal disease caused by preterm birth., PMID:34667204
Circulating extracellular vesicles of patients with steroid-sensitive nephrotic syndrome have higher RAC1 and induce recapitulation of nephrotic syndrome phenotype in podocytes., PMID:34569252
Urinary mRNA Expression of Glomerular Podocyte Markers in Glomerular Disease and Renal Transplant., PMID:34441433
Identification of key carcinogenic genes in Wilms' tumor., PMID:34334530
In situ strategy for biomedical target localization via nanogold nucleation and secondary growth., PMID:34112923
Synaptopodin deficiency exacerbates kidney disease in a mouse model of Alport syndrome., PMID:34029143
Neuronal exosome proteins: novel biomarkers for predicting neonatal response to therapeutic hypothermia., PMID:34021027
All-trans retinoic acid induces synaptic plasticity in human cortical neurons., PMID:33781382
High levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus., PMID:33580102
Podocyte Injury Through Interaction Between Tlr8 and Its Endogenous Ligand miR-21 in Obstructed and Its Collateral Kidney., PMID:33552064
Fetal Central Nervous System Derived Extracellular Vesicles: Potential for Non-invasive Tracking of Viral Mediated Fetal Brain Injury., PMID:40012720
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1-associated membranous nephropathy., PMID:33351779
Therapeutic potential of human induced pluripotent stem cells and renal progenitor cells in experimental chronic kidney disease., PMID:33298161
The actin-modulating protein synaptopodin mediates long-term survival of dendritic spines., PMID:33275099
Identification of potential gene drivers of cutaneous squamous cell carcinoma: Analysis of microarray data., PMID:32991423
Protective effects of DPP-4 inhibitor on podocyte injury in glomerular diseases., PMID:32948146
Synaptopodin Is Dispensable for Normal Podocyte Homeostasis but Is Protective in the Context of Acute Podocyte Injury., PMID:32938649
Podocyte Involvement in Renal Thrombotic Microangiopathy: A Clinicopathological Study., PMID:32862175
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1., PMID:32560811
Spatio-temporal patterning of different connexins in developing and postnatal human kidneys and in nephrotic syndrome of the Finnish type (CNF)., PMID:32471989
Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin., PMID:32398370
Genetic ablation of SLK exacerbates glomerular injury in adriamycin nephrosis in mice., PMID:32308020
PLCE1 regulates the migration, proliferation, and differentiation of podocytes., PMID:32238860
Mesenchymal Stromal Cells Induce Podocyte Protection in the Puromycin Injury Model., PMID:31862892
Granule Cell Ensembles in Mouse Dentate Gyrus Rapidly Upregulate the Plasticity-Related Protein Synaptopodin after Exploration Behavior., PMID:31812981
Intrinsic disorder and amino acid specificity modulate binding of the WW2 domain in kidney and brain protein (KIBRA) to synaptopodin., PMID:31597702
For research use only. Not for human or drug use.
