Catalog No.
YHJ19201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg731-Asp980
Predicted molecular weight
30.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8IWV2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Contactin-4, BIG-2, Brain-derived immunoglobulin superfamily protein 2, CNTN4
Finding Potential Drug Targets for Pre-Eclampsia Using Mendelian Randomisation and Colocalisation Analysis., PMID:40028697
Identification of Genetic Factors Related With Nonhereditary Colorectal Polyposis and Its Recurrence Through Genome-Wide Association Study., PMID:39629711
Contactin-4 suppresses antitumor T cell responses by engaging amyloid precursor protein., PMID:39392894
Contactin proteins in cerebrospinal fluid show different alterations in dementias., PMID:39317877
Proteomics of left ventricular structure in the Multi-Ethnic Study of Atherosclerosis., PMID:39263947
CNTN4 modulates neural elongation through interplay with APP., PMID:38745463
Whole-genome resequencing of Chinese indigenous sheep provides insight into the genetic basis underlying climate adaptation., PMID:38565986
Potential Schizophrenia Disease-Related Genes Prediction Using Metagraph Representations Based on a Protein-Protein Interaction Keyword Network: Framework Development and Validation., PMID:37966892
Rare recurrent copy number variations in metabotropic glutamate receptor interacting genes in children with neurodevelopmental disorders., PMID:37120522
MiR-148a-3p attenuates apoptosis and inflammation by targeting CNTN4 in atherosclerosis., PMID:36544657
Value of Immunohistochemical Expression of Apelin, Succinate Dehydrogenase B, Chromogranin B, Human Epidermal Growth Factor Receptor-2, Contactin 4, and Succinyl-CoA Synthetase Subunit Beta in Differentiating Metastatic From Non-Metastatic Pheochromocytoma and Paraganglioma., PMID:35574028
The expression discrepancy and characteristics of long non-coding RNAs in peripheral blood leukocytes from amyotrophic lateral sclerosis patients., PMID:35364800
Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface., PMID:34958801
The autism risk gene CNTN4 modulates dendritic spine formation., PMID:34415325
Several Fusion Genes Identified in a Spermatic Cord Leiomyoma With Rearrangements of Chromosome Arms 3p and 21q., PMID:34183386
Multi-omics analysis of genomics, epigenomics and transcriptomics for molecular subtypes and core genes for lung adenocarcinoma., PMID:33750346
Genetic risk score constructed from common genetic variants is associated with cardiovascular disease risk in type 2 diabetes mellitus., PMID:33350037
Exploring the Role of Contactins across Psychological, Psychiatric and Cardiometabolic Traits within UK Biobank., PMID:33182605
Genetic determinants of ammonia-induced acute lung injury in mice., PMID:33050709
Neuronal migration genes and a familial translocation t (3;17): candidate genes implicated in the phenotype., PMID:32028920
Intragenic CNTN4 copy number variants associated with a spectrum of neurobehavioral phenotypes., PMID:31422286
Clinical and Molecular Characterization of Two Patients with CNTN6 Copy Number Variations., PMID:30508811
A Meta-Analysis Including Pre-selected Sequence Variants Associated With Seven Traits in Three French Dairy Cattle Populations., PMID:30459810
Heterogeneity of Cell Surface Glutamate and GABA Receptor Expression in Shank and CNTN4 Autism Mouse Models., PMID:29970989
Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study., PMID:29503163
Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A2 formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)., PMID:29258006
Expression of Contactin 4 Is Associated With Malignant Behavior in Pheochromocytomas and Paragangliomas., PMID:28938490
Nanomechanics of multidomain neuronal cell adhesion protein contactin revealed by single molecule AFM and SMD., PMID:28821864
Investigating the effect of different transducer stiffness values on the contactin complex detachment by steered molecular dynamics., PMID:28651183
Single nucleotide polymorphisms in an Indian cohort and association of CNTN4, MMP2 and SNTB1 variants with oral cancer., PMID:28595731
Constitutional 3p26.3 terminal microdeletion in an adolescent with neuroblastoma., PMID:28402723
A current view on contactin-4, -5, and -6: Implications in neurodevelopmental disorders., PMID:28064060
Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1., PMID:28044437
Psychophysiological endophenotypes to characterize mechanisms of known schizophrenia genetic loci., PMID:27995817
Distortion of the normal function of synaptic cell adhesion molecules by genetic variants as a risk for autism spectrum disorders., PMID:27743928
Investigating the effects of copy number variants on reading and language performance., PMID:27186239
Polymorphism of rs3737597 in DISC1 Gene on Chromosome 1q42.2 in sALS Patients: a Chinese Han Population Case-Control Study., PMID:27052956
GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans., PMID:27039371
Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use., PMID:26146898
Contactin-4 mediates axon-target specificity and functional development of the accessory optic system., PMID:25959733
Single gene microdeletions and microduplication of 3p26.3 in three unrelated families: CNTN6 as a new candidate gene for intellectual disability., PMID:25606055
Neurodevelopmental disorders associated with dosage imbalance of ZBTB20 correlate with the morbidity spectrum of ZBTB20 candidate target genes., PMID:25062845
Gene-rich large deletions are overrepresented in POAG patients of Indian and Caucasian origins., PMID:24764060
Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue., PMID:24659297
Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations., PMID:24529757
ChIP-seq analysis of histone H3K9 trimethylation in peripheral blood mononuclear cells of membranous nephropathy patients., PMID:24345872
Genetic factors associated with gemcitabine pharmacokinetics, disposition, and toxicity., PMID:24225399
A genome-wide survey of transgenerational genetic effects in autism., PMID:24204716
Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis., PMID:23922650
Sphingosine-1-phosphate can promote mast cell hyper-reactivity through regulation of contactin-4 expression., PMID:23904439
For research use only. Not for human or drug use.
