Catalog No.
YHJ18301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr71-Met239
Predicted molecular weight
21.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8IUN9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD301, Macrophage lectin 2, C-type lectin domain family 10 member A, CLECSF13, C-type lectin superfamily member 14, CLEC10A, CLECSF14, HML
Oxylipins and metabolites from pyroptotic cells act as promoters of tissue repair., PMID:38926576
Glycan Structures in Osteosarcoma as Targets for Lectin-Based Chimeric Antigen Receptor Immunotherapy., PMID:38791381
Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue., PMID:38678562
CD301 and LSECtin glycan-binding receptors of innate immune cells serve as prognostic markers and potential predictors of immune response in breast cancer subtypes., PMID:38206856
Ligand Recognition by the Macrophage Galactose-Type C-Type Lectin: Self or Non-Self?-A Way to Trick the Host's Immune System., PMID:38069400
Tn antigen interactions of macrophage galactose-type lectin (MGL) in immune function and disease., PMID:37847609
Targeting CD301+ macrophages inhibits endometrial fibrosis and improves pregnancy outcome., PMID:37519221
Glyco-binding domain chimeric antigen receptors as a new option for cancer immunotherapy., PMID:36529796
CD301 mediates fusion in IL-4-driven multinucleated giant cell formation., PMID:33571108
Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin., PMID:33560106
Subsets of CD1c+ DCs: Dendritic Cell Versus Monocyte Lineage., PMID:33101275
Investigating Patterns of Immune Interaction in Ovarian Cancer: Probing the O-glycoproteome by the Macrophage Galactose-Like C-type Lectin (MGL)., PMID:33019700
SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors., PMID:32766577
N-Glycoproteins Have a Major Role in MGL Binding to Colorectal Cancer Cell Lines: Associations with Overall Proteome Diversity., PMID:32752259
ASGR1 and Its Enigmatic Relative, CLEC10A., PMID:32650396
RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages., PMID:32477357
Adipose-resident myeloid-derived suppressor cells modulate immune cell homeostasis in healthy mice., PMID:32392367
Sensing Tissue Damage by Myeloid C-Type Lectin Receptors., PMID:31974758
ICH3, a selective alpha7 nicotinic acetylcholine receptor agonist, modulates adipocyte inflammation associated with obesity., PMID:31965518
Immature O-glycans recognized by the macrophage glycoreceptor CLEC10A (MGL) are induced by 4-hydroxy-tamoxifen, oxidative stress and DNA-damage in breast cancer cells., PMID:31455323
Blockade of Lymphangiogenesis Shapes Tumor-Promoting Adipose Tissue Inflammation., PMID:31369756
The C-type lectin receptor MGL senses N-acetylgalactosamine on the unique Staphylococcus aureus ST395 wall teichoic acid., PMID:31219660
MicroRNA-99a mimics inhibit M1 macrophage phenotype and adipose tissue inflammation by targeting TNFα., PMID:29849090
CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion., PMID:29755453
An innovative immunotherapeutic strategy for ovarian cancer: CLEC10A and glycomimetic peptides., PMID:29665849
A Critical Domain of Ebolavirus Envelope Glycoprotein Determines Glycoform and Infectivity., PMID:29615747
Mannosylated T/Tn with Freund's adjuvant induces cellular immunity., PMID:29251002
Specific and Differential Binding of N-Acetylgalactosamine Glycopolymers to the Human Macrophage Galactose Lectin and Asialoglycoprotein Receptor., PMID:28418238
Nanostructured glycopolymer augmented liposomes to elucidate carbohydrate-mediated targeting., PMID:27184097
TIPE2 regulates tumor-associated macrophages in skin squamous cell carcinoma., PMID:26577853
In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice., PMID:26376185
Bi- to tetravalent glycoclusters presenting GlcNAc/GalNAc as inhibitors: from plant agglutinins to human macrophage galactose-type lectin (CD301) and galectins., PMID:25721929
Rhinovirus infection induces interleukin-13 production from CD11b-positive, M2-polarized exudative macrophages., PMID:25029349
Macrophages regulate renal fibrosis through modulating TGFβ superfamily signaling., PMID:24929555
Macrophage activation state determines the response to rhinovirus infection in a mouse model of allergic asthma., PMID:24907978
Overexpression of IL-10 in C2D macrophages promotes a macrophage phenotypic switch in adipose tissue environments., PMID:24466141
Identification of novel dendritic cell subset markers in human blood., PMID:24321550
Arginase activity is associated with fibrosis in experimental infection with Taenia crassiceps, but does not play a major role in resistance to infection., PMID:24090570
Expression of activating transcription factor 2 in inflammatory macrophages in obese adipose tissue., PMID:23712976
Tumor-associated Neu5Ac-Tn and Neu5Gc-Tn antigens bind to C-type lectin CLEC10A (CD301, MGL)., PMID:23507963
Protein domain histochemistry (PDH): binding of the carbohydrate recognition domain (CRD) of recombinant human glycoreceptor CLEC10A (CD301) to formalin-fixed, paraffin-embedded breast cancer tissues., PMID:23275449
Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis., PMID:22614697
Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice., PMID:21821915
Targeted deletion of adipocytes by apoptosis leads to adipose tissue recruitment of alternatively activated M2 macrophages., PMID:21693678
Involvement of viral envelope GP2 in Ebola virus entry into cells expressing the macrophage galactose-type C-type lectin., PMID:21362405
M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis., PMID:21356378
Differential expression of monocyte/macrophage- selective markers in human idiopathic pulmonary fibrosis., PMID:21309737
Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells., PMID:20304916
MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity., PMID:19995956
Properties of blocking and non-blocking monoclonal antibodies specific for human macrophage galactose-type C-type lectin (MGL/ClecSF10A/CD301)., PMID:17167039
For research use only. Not for human or drug use.
