Catalog No.
YHJ16201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Cys309
Predicted molecular weight
36.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q86V86
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PIM3, Serine/threonine-protein kinase pim-3
Characterization of m6A-Related Genes in Tumor-Associated Macrophages for Prognosis, Immunotherapy, and Drug Prediction in Lung Adenocarcinomas Based on Machine Learning Algorithms., PMID:40474570
Lipopolysaccharide (LPS)-Induced Tumor Necrosis Factor-Alpha (TNF-ɑ) Levels and Health Care Associated Infection (HAI) in Children with Multi-Organ Dysfunction Syndrome (MODS)., PMID:40208383
ETS1 modulates ferroptosis to affect the process of myocardial ischemia-reperfusion injury via PIM3., PMID:40189183
Targeting of PIM Kinases Shows Single Agent Efficacy and Synergizes With BCL2 Inhibitors in Diffuse Large B Cell Lymphoma of the ABC Subtype., PMID:40040616
Pim3 up-regulation by YY1 contributes to diabetes-induced cardiac hypertrophy and heart failure., PMID:39850120
Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties., PMID:39830340
A putative mycobacterial GDP-mannose dependent α-mannosyltransferase Rv0225 acts as PimC: an in-silico study., PMID:39660564
Endothelial Pim3 kinase protects the vascular barrier during lung metastasis., PMID:39627185
Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway., PMID:39507762
PIM1 kinase and its diverse substrate in solid tumors., PMID:39487435
PIM Kinase Inhibitors as Novel Promising Therapeutic Scaffolds in Cancer Therapy., PMID:39297470
The role of Pim-1 kinases in inflammatory signaling pathways., PMID:39079978
UM171 suppresses breast cancer progression by inducing KLF2., PMID:38874684
PIM kinase inhibitors: an updated patent review (2016-present)., PMID:38842051
A review on structure-function mechanism and signaling pathway of serine/threonine protein PIM kinases as a therapeutic target., PMID:38704069
PIM Kinase Inhibition Sensitizes Neuroblastoma to Doxorubicin., PMID:38570263
PIM Kinases as Potential Biomarkers and Therapeutic Targets in Inflammatory Arthritides., PMID:38542097
Synthesis, kinase inhibition and anti-leukemic activities of diversely substituted indolopyrazolocarbazoles., PMID:38537512
Identification and assessment of new PIM2 inhibitors for treating hematologic cancers: A combined approach of energy-based virtual screening and machine learning evaluation., PMID:38263717
PIM Kinase Inhibition Attenuates the Malignant Progression of Metastatic Hepatoblastoma., PMID:38203596
Comprehensive Insights that Targeting PIM for Cancer Therapy: Prospects and Obstacles., PMID:38164076
PIM3 regulates myocardial ischemia/reperfusion injury via ferroptosis., PMID:38148455
Corynoline inhibits esophageal squamous cell carcinoma growth via targeting Pim-3., PMID:38128397
Panel-based RNA fusion sequencing improves diagnostics of pediatric acute myeloid leukemia., PMID:38086945
Targeting PIM kinases in cancer therapy: An update on pharmacological small-molecule inhibitors., PMID:38071792
PIM kinases regulate early human Th17 cell differentiation., PMID:38039135
Predictive Value of PRISM-4, PIM-3, CRP, Albumin, CRP/Albumin Ratio and Lactate in Critically Ill Children., PMID:38002822
AUM302, a novel triple kinase PIM/PI3K/mTOR inhibitor, is a potent in vitro pancreatic cancer growth inhibitor., PMID:37943821
Effect of intravenous immunoglobulin on the outcome of children with septic shock in a PICU: a retrospective cohort study., PMID:37733114
Nomogram to predict feeding intolerance in critically ill children., PMID:37723295
Pim Kinases: Important Regulators of Cardiovascular Disease., PMID:37511341
LncRNA SNHG1 Accelerates Cell Proliferation, Migration, and Invasion of Hepatoblastoma Through Mediating miR-6838-5p/PIM3/RhoA Axis., PMID:37248373
Identifying the potential transcriptional regulatory network in Hirschsprung disease by integrated analysis of microarray datasets., PMID:37082700
CDK9 inhibition induces epigenetic reprogramming revealing strategies to circumvent resistance in lymphoma., PMID:36998071
Inhibition of PIM Kinases Promotes Neuroblastoma Cell Differentiation to a Neuronal Phenotype., PMID:36907773
Targeting Pim kinases in hematological cancers: molecular and clinical review., PMID:36694243
A t(4;13)(q21;q14) translocation in B-cell chronic lymphocytic leukemia causing concomitant homozygous DLEU2/miR15a/miR16-1 and heterozygous ARHGAP24 deletions., PMID:36641997
PIM3 kinase promotes tumor metastasis in hepatoblastoma by upregulating cell surface expression of chemokine receptor cxcr4., PMID:36315303
Comparing outcomes between culture-positive and culture-negative septic shock in a PICU: A retrospective cohort study., PMID:36313890
PIM3-AMPK-HDAC4/5 axis restricts MuERVL-marked 2-cell-like state in embryonic stem cells., PMID:36150380
Biochemical indicators of euthyroid sick syndrome in critically ill children., PMID:36106490
Development of novel cyanopyridines as PIM-1 kinase inhibitors with potent anti-prostate cancer activity: Synthesis, biological evaluation, nanoparticles formulation and molecular dynamics simulation., PMID:36084418
Long non-coding RNA long intergenic non-protein coding RNA 1232 promotes cell proliferation, migration and invasion in bladder cancer via modulating miR-370-5p/PIM3 axis., PMID:35338769
Feedback Loop Regulation between Pim Kinases and Tax Keeps Human T-Cell Leukemia Virus Type 1 Viral Replication in Check., PMID:34818069
Inhibition of PIM Kinases in DLBCL Targets MYC Transcriptional Program and Augments the Efficacy of Anti-CD20 Antibodies., PMID:34625423
Optimization of 4,6-Disubstituted Pyrido[3,2-d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth., PMID:34515481
LncRNA RGMB-AS1 facilitates pancreatic cancer cell proliferation and migration but inhibits cell apoptosis via miR-574-3p/PIM3 axis., PMID:34468207
Therapeutic targeting of PIM KINASE signaling in cancer therapy: Structural and clinical prospects., PMID:34455019
Co-Targeting PIM Kinase and PI3K/mTOR in NSCLC., PMID:33946744
Expression and ERG regulation of PIM kinases in prostate cancer., PMID:33932111
For research use only. Not for human or drug use.
