Catalog No.
YHJ15901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro218-Arg479
Predicted molecular weight
55.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q86UP6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CUB and zona pellucida-like domain-containing protein 1, Transmembrane protein UO-44, CUB and ZP domain-containing protein 1, CUZD1
Local genetic covariance analysis with lipid traits identifies novel loci for early-onset Alzheimer's Disease., PMID:40096060
Candidate Biomarkers for Targeting in Type 1 Diabetes; A Bioinformatic Analysis of Pancreatic Cell Surface Antigens., PMID:38351729
Association analysis of CUZD1 variants in European chronic pancreatitis patients., PMID:37858432
Plasma proteins as potential biomarkers of aging of single tissue and cell type., PMID:37707684
Variants in the pancreatic CUB and zona pellucida-like domains 1 (CUZD1) gene in early-onset chronic pancreatitis - A possible new susceptibility gene., PMID:35589511
Comparative Study of the Effect of Macrolide Antibiotics Erythromycin, Clarithromycin, and Azithromycin on the ERG1 Gene Expression in H9c2 Cardiomyoblast Cells., PMID:32559772
Mu opioid receptors in the medial preoptic area govern social play behavior in adolescent male rats., PMID:32388931
Pancreatic anti-GP2 and anti-Saccharomyces cerevisiae antibodies in ruminants with paratuberculosis: A better understanding of the immunopathogenesis of Crohn's disease., PMID:32035824
A proteome-wide immuno-mass spectrometric identification of serum autoantibodies., PMID:31249498
Significance of serological markers in the disease course of ulcerative colitis in a prospective clinical cohort of patients., PMID:29590158
Aberrantly high expression of the CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in mammary epithelium leads to breast tumorigenesis., PMID:29321207
Differential DNA Methylation in Monozygotic Twins Discordant for Female Sexual Functioning., PMID:28964710
Generation of monoclonal antibodies and development of an immunofluorometric assay for the detection of CUZD1 in tissues and biological fluids., PMID:28746862
Novel immunoassays for detection of CUZD1 autoantibodies in serum of patients with inflammatory bowel diseases., PMID:28343172
CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy., PMID:28278176
Autoimmunity in Crohn's Disease-A Putative Stratification Factor of the Clinical Phenotype., PMID:27717419
Transient and Prolonged Response of Chicken Cecum Mucosa to Colonization with Different Gut Microbiota., PMID:27685470
Autoantibodies against glutamate receptor δ2 after allogenic stem cell transplantation., PMID:27458598
Variants of contextual fear conditioning induce differential patterns of Egr-1 activity within the young adult prefrontal cortex., PMID:26778782
Disrupting astrocyte-neuron lactate transfer persistently reduces conditioned responses to cocaine., PMID:26503760
Diagnostic and clinical significance of Crohn's disease-specific pancreatic anti-GP2 and anti-CUZD1 antibodies., PMID:26351932
Pancreatic Autoantibodies Against CUZD1 and GP2 Are Associated with Distinct Clinical Phenotypes of Crohn's Disease., PMID:26273818
Reproducibility crisis: Blame it on the antibodies., PMID:25993940
Rediscovery of the Anti-Pancreatic Antibodies and Evaluation of their Prognostic Value in a Prospective Clinical Cohort of Crohn's Patients: The Importance of Specific Target Antigens [GP2 and CUZD1]., PMID:25968583
RNA sequencing to study gene expression and SNP variations associated with growth in zebrafish fed a plant protein-based diet., PMID:25702041
Crohn's disease-specific anti-CUZD1 pancreatic antibodies are absent in ruminants with paratuberculosis., PMID:25575461
Serological studies in inflammatory bowel disease: how important are they?, PMID:24811052
False biomarker discovery due to reactivity of a commercial ELISA for CUZD1 with cancer antigen CA125., PMID:24097894
CUZD1 and anti-CUZD1 antibodies as markers of cancer and inflammatory bowel diseases., PMID:23710207
Reply to Dr. Roggenbuck et al.'s letter., PMID:23466410
Loss of tolerance to one or two major targets in Crohn's disease or just cross-reactivity?, PMID:23337370
Editorial comment on Leung et al.: CUB and zona pellucida-like domain-containing protein 1 (CUZD1): a novel serological biomarker for ovarian cancer., PMID:23200087
Autoantibodies against exocrine pancreas in Crohn's disease are directed against two antigens: the glycoproteins CUZD1 and GP2., PMID:23140841
CUB and zona pellucida-like domain-containing protein 1 (CUZD1): a novel serological biomarker for ovarian cancer., PMID:22985796
Diagnostic value, clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn's disease specific-pancreatic autoantibodies., PMID:21983481
Repeated electroconvulsive seizure treatment in rats reduces inducibility of early growth response genes and hyperactivity in response to cocaine administration., PMID:21334415
PACAP-regulated phenylethanolamine N-methyltransferase gene expression., PMID:21039521
The origins of human embryonic stem cells: a biological conundrum., PMID:18160822
Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro., PMID:16862170
Identification and characterization of novel and unknown mouse epididymis-specific genes by complementary DNA microarray technology., PMID:16707773
Abnormal expression of epilepsy-related gene ERG1/NSF in the spontaneous recurrent seizure rats with spatial learning memory deficits induced by kainic acid., PMID:16039622
Expression of egr-1 (zif268) mRNA in select fear-related brain regions following exposure to a predator., PMID:15970222
An egr-1 (zif268) antisense oligodeoxynucleotide infused into the amygdala disrupts fear conditioning., PMID:15466317
Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane-associated protein, UO-44., PMID:15184879
Cocaine- and alcohol-mediated expression of inducible transcription factors is blocked by pentobarbital anesthesia., PMID:10986339
Cloning and uterus/oviduct-specific expression of a novel estrogen-regulated gene (ERG1)., PMID:10542259
For research use only. Not for human or drug use.
